BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

Click here to switch to the map view.

The map label for this gene is ccmA [H]

Identifier: 146337538

GI number: 146337538

Start: 396101

End: 396724

Strand: Reverse

Name: ccmA [H]

Synonym: BRADO0392

Alternate gene names: 146337538

Gene position: 396724-396101 (Counterclockwise)

Preceding gene: 146337542

Following gene: 146337537

Centisome position: 5.32

GC content: 71.15

Gene sequence:

>624_bases
ATGCAGCAGTCTCCACCACCGTCTCCGAGGCTGTTCGGACACGACGTCAGATGCGTGCGCGGCGGCCGCGAGGTGTTTGC
CGGTCTTGCCTTCGAGGCGCGCGCGGGCGAGGCGCTGGCCGTGACCGGGCACAATGGCGCCGGCAAGACCTCGCTGCTGC
GGCTGATCGCGGGCCTCCTGCTGCCGACCGGCGGCACGATCGCCATCGAGGGCGGCGGGGGCGAGCTGACGGTGCCAGAG
CAGGCGCATTATCTCGGCCACCGCGACGCGCTGAAGCCGGCGCTCAGCGTGCGTGAGAACCTGACATTCTGGGCCGACTT
CCTCGGCGGCGGAATGACGCGCCCGATCCCGGATTGCCTCGCGGCCGTCGGCATCGCGCACGCGATTGATCTGCCCGCGG
GCTACCTCTCCGCCGGCCAGCGCCGCCGCCTATCCCTGGCCCGCCTCCTCGCCGTGCCCCGCCTGCTCTGGCTGCTCGAC
GAGCCGACCGCGGCACTCGACGTCACCGGACAGGCGATGTTCGCCGGCCTGATGCGCGAGCATCTAGCAACGGGTGGGCT
GATCGTCGCCGCCACGCACGGGCCGCTCGGCATCGACACACGCGAACTGCGGATTGGAAACTGA

Upstream 100 bases:

>100_bases
CTAACTGCGTCGCTACAGAGACAATCAAGTCCCGGCGTGGCATCACCCACAAATTCTCGCACGCTAGCCATCAATTTCGT
AAGGGCTGTCACGACGCGCC

Downstream 100 bases:

>100_bases
GCTGATGTTTATGGGACAGGCAATTTTTCACCGCGACATCGGTGCGCCCCCCTCCCCCTTGCGGGGAGGGGTCGGGGGTG
GGGGTCCCAGCAAAGACTGC

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQQSPPPSPRLFGHDVRCVRGGREVFAGLAFEARAGEALAVTGHNGAGKTSLLRLIAGLLLPTGGTIAIEGGGGELTVPE
QAHYLGHRDALKPALSVRENLTFWADFLGGGMTRPIPDCLAAVGIAHAIDLPAGYLSAGQRRRLSLARLLAVPRLLWLLD
EPTAALDVTGQAMFAGLMREHLATGGLIVAATHGPLGIDTRELRIGN

Sequences:

>Translated_207_residues
MQQSPPPSPRLFGHDVRCVRGGREVFAGLAFEARAGEALAVTGHNGAGKTSLLRLIAGLLLPTGGTIAIEGGGGELTVPE
QAHYLGHRDALKPALSVRENLTFWADFLGGGMTRPIPDCLAAVGIAHAIDLPAGYLSAGQRRRLSLARLLAVPRLLWLLD
EPTAALDVTGQAMFAGLMREHLATGGLIVAATHGPLGIDTRELRIGN
>Mature_207_residues
MQQSPPPSPRLFGHDVRCVRGGREVFAGLAFEARAGEALAVTGHNGAGKTSLLRLIAGLLLPTGGTIAIEGGGGELTVPE
QAHYLGHRDALKPALSVRENLTFWADFLGGGMTRPIPDCLAAVGIAHAIDLPAGYLSAGQRRRLSLARLLAVPRLLWLLD
EPTAALDVTGQAMFAGLMREHLATGGLIVAATHGPLGIDTRELRIGN

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI6005701, Length=147, Percent_Identity=34.0136054421769, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27477115, Length=158, Percent_Identity=31.6455696202532, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI153792144, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI27436953, Length=172, Percent_Identity=31.9767441860465, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI46592971, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI46592964, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592915, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592898, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592978, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI46592956, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI105990541, Length=178, Percent_Identity=29.7752808988764, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI47078218, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI45446740, Length=173, Percent_Identity=30.635838150289, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI116734710, Length=165, Percent_Identity=30.9090909090909, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI9665248, Length=178, Percent_Identity=30.8988764044944, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082064, Length=198, Percent_Identity=38.3838383838384, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787792, Length=199, Percent_Identity=33.1658291457286, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1786698, Length=214, Percent_Identity=30.3738317757009, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788165, Length=174, Percent_Identity=35.0574712643678, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788210, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788761, Length=189, Percent_Identity=29.1005291005291, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=182, Percent_Identity=34.0659340659341, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI2367384, Length=170, Percent_Identity=32.9411764705882, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=183, Percent_Identity=28.9617486338798, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=30.2884615384615, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790190, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48995001, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787182, Length=149, Percent_Identity=34.2281879194631, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787712, Length=193, Percent_Identity=31.0880829015544, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786253, Length=152, Percent_Identity=34.2105263157895, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI87081791, Length=151, Percent_Identity=31.7880794701987, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788225, Length=167, Percent_Identity=32.3353293413174, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI87081709, Length=165, Percent_Identity=29.0909090909091, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788897, Length=183, Percent_Identity=29.5081967213115, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=175, Percent_Identity=30.2857142857143, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19920532, Length=185, Percent_Identity=31.3513513513514, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580930, Length=185, Percent_Identity=31.3513513513514, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574533, Length=185, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076682, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076684, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581617, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581615, Length=184, Percent_Identity=28.804347826087, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648314, Length=157, Percent_Identity=29.9363057324841, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28574744, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221512771, Length=180, Percent_Identity=26.1111111111111, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24662800, Length=181, Percent_Identity=29.2817679558011, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24666092, Length=198, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 21671; Mature: 21671

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS00144 ASN_GLN_ASE_1 ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSPPPSPRLFGHDVRCVRGGREVFAGLAFEARAGEALAVTGHNGAGKTSLLRLIAGLL
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHHHH
LPTGGTIAIEGGGGELTVPEQAHYLGHRDALKPALSVRENLTFWADFLGGGMTRPIPDCL
CCCCCEEEEECCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AAVGIAHAIDLPAGYLSAGQRRRLSLARLLAVPRLLWLLDEPTAALDVTGQAMFAGLMRE
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHH
HLATGGLIVAATHGPLGIDTRELRIGN
HHCCCCEEEEECCCCCCCCCCEEEECC
>Mature Secondary Structure
MQQSPPPSPRLFGHDVRCVRGGREVFAGLAFEARAGEALAVTGHNGAGKTSLLRLIAGLL
CCCCCCCCCCCCCCCHHHHHCCHHHHHHHHEECCCCCEEEEECCCCCCHHHHHHHHHHHH
LPTGGTIAIEGGGGELTVPEQAHYLGHRDALKPALSVRENLTFWADFLGGGMTRPIPDCL
CCCCCEEEEECCCCEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
AAVGIAHAIDLPAGYLSAGQRRRLSLARLLAVPRLLWLLDEPTAALDVTGQAMFAGLMRE
HHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHH
HLATGGLIVAATHGPLGIDTRELRIGN
HHCCCCEEEEECCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA