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The map label for this gene is sdhB [H]

Identifier: 146337400

GI number: 146337400

Start: 251018

End: 251800

Strand: Direct

Name: sdhB [H]

Synonym: BRADO0235

Alternate gene names: 146337400

Gene position: 251018-251800 (Clockwise)

Preceding gene: 146337399

Following gene: 146337401

Centisome position: 3.37

GC content: 62.96

Gene sequence:

>783_bases
ATGGCTGAGTTCGCACTTCCGAAGAATTCCCAGATCACCGGCGGCAAGACCTGGCCGAAGCCGGCGGGCGCCACCGAAGT
CCGCGAGTTCAAGGTCTATCGCTGGAATCCGGACGACGGCAAGAATCCGAGCGTCGACACCTATTACGTCGACGTCAATG
ATTGCGGTCCGATGGTGCTCGACGGCCTGATCTGGATCAAGAACCACATTGATCCGTCGCTGACCTTCCGCCGCTCCTGC
CGCGAAGGCGTATGCGGCTCCTGCGCGATGAACATCGACGGCCAGAATACGCTGGCCTGCACGCGCTCGATGCACGACGT
GAAGGATGGCGCGGTCAAGATCAACCCGCTGCCGCACCAGCCGGTGGTGAAGGACCTCGTGCCCGACCTCACGAACTTCT
ACGCGCAATACGCTTCGATCGAGCCGTGGCTGAAGACCACCACGCCGACGCCGCAGAAGGAATGGAAGCAGACCCACGAG
GATCGCGAGAAGCTCGACGGCCTCTACGAGTGCATCCTGTGCGCCTGCTGCTCGACCTCGTGCCCGAGCTACTGGTGGAA
CAGCGAGCGCTATCTCGGACCGGCAGCGCTTTTGCAGGCGACGCGCTGGGTCAAGGACAGCCGCGACGAGGCGACCGGCG
AGCGGCTCGACAATCTCGAGGATCCGTTCCGTCTGTACCGTTGCCATACGATCATGAACTGCGCCAAGGCCTGCCCGAAG
GGGCTCAACCCGGCCGAAGCGATCGCCGAGCTGAAGCTCAAGCTGGTCGAGCGGCAGATCTGA

Upstream 100 bases:

>100_bases
ACCATGACCAACGACGTGCAGTATATTCCGCCGAAGGCACGCGTCTACTGATCGCGCGTGTGCCGAGCCCGTCCGTCAAA
ACCTGAGAAGGCCTATCGAA

Downstream 100 bases:

>100_bases
CCGAGCAGCAAGGGTAATATATCATTGCGCCCGGGCCCGTCGGAAGTTCCGGGCGCAGCTGATTTTGTAGCTGACGCCGA
TTGCGATAAGCTCTCAGCCT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEFALPKNSQITGGKTWPKPAGATEVREFKVYRWNPDDGKNPSVDTYYVDVNDCGPMVLDGLIWIKNHIDPSLTFRRSC
REGVCGSCAMNIDGQNTLACTRSMHDVKDGAVKINPLPHQPVVKDLVPDLTNFYAQYASIEPWLKTTTPTPQKEWKQTHE
DREKLDGLYECILCACCSTSCPSYWWNSERYLGPAALLQATRWVKDSRDEATGERLDNLEDPFRLYRCHTIMNCAKACPK
GLNPAEAIAELKLKLVERQI

Sequences:

>Translated_260_residues
MAEFALPKNSQITGGKTWPKPAGATEVREFKVYRWNPDDGKNPSVDTYYVDVNDCGPMVLDGLIWIKNHIDPSLTFRRSC
REGVCGSCAMNIDGQNTLACTRSMHDVKDGAVKINPLPHQPVVKDLVPDLTNFYAQYASIEPWLKTTTPTPQKEWKQTHE
DREKLDGLYECILCACCSTSCPSYWWNSERYLGPAALLQATRWVKDSRDEATGERLDNLEDPFRLYRCHTIMNCAKACPK
GLNPAEAIAELKLKLVERQI
>Mature_259_residues
AEFALPKNSQITGGKTWPKPAGATEVREFKVYRWNPDDGKNPSVDTYYVDVNDCGPMVLDGLIWIKNHIDPSLTFRRSCR
EGVCGSCAMNIDGQNTLACTRSMHDVKDGAVKINPLPHQPVVKDLVPDLTNFYAQYASIEPWLKTTTPTPQKEWKQTHED
REKLDGLYECILCACCSTSCPSYWWNSERYLGPAALLQATRWVKDSRDEATGERLDNLEDPFRLYRCHTIMNCAKACPKG
LNPAEAIAELKLKLVERQI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=234, Percent_Identity=64.957264957265, Blast_Score=329, Evalue=1e-90,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=52.1367521367521, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1790596, Length=227, Percent_Identity=33.920704845815, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17533915, Length=230, Percent_Identity=60, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=232, Percent_Identity=62.9310344827586, Blast_Score=308, Evalue=5e-85,
Organism=Drosophila melanogaster, GI17137106, Length=239, Percent_Identity=62.3430962343096, Blast_Score=330, Evalue=8e-91,
Organism=Drosophila melanogaster, GI24643156, Length=238, Percent_Identity=60.0840336134454, Blast_Score=301, Evalue=3e-82,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29415; Mature: 29283

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFALPKNSQITGGKTWPKPAGATEVREFKVYRWNPDDGKNPSVDTYYVDVNDCGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DGLIWIKNHIDPSLTFRRSCREGVCGSCAMNIDGQNTLACTRSMHDVKDGAVKINPLPHQ
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCC
PVVKDLVPDLTNFYAQYASIEPWLKTTTPTPQKEWKQTHEDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSERYLGPAALLQATRWVKDSRDEATGERLDNLEDPFRLYRCHTIMNCAKACPK
CCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
GLNPAEAIAELKLKLVERQI
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEFALPKNSQITGGKTWPKPAGATEVREFKVYRWNPDDGKNPSVDTYYVDVNDCGPMVL
CCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCEEEEEECCCCCHHHH
DGLIWIKNHIDPSLTFRRSCREGVCGSCAMNIDGQNTLACTRSMHDVKDGAVKINPLPHQ
HHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEECCCCCC
PVVKDLVPDLTNFYAQYASIEPWLKTTTPTPQKEWKQTHEDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSERYLGPAALLQATRWVKDSRDEATGERLDNLEDPFRLYRCHTIMNCAKACPK
CCCHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
GLNPAEAIAELKLKLVERQI
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA