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The map label for this gene is atoS [C]

Identifier: 146337401

GI number: 146337401

Start: 251919

End: 254069

Strand: Direct

Name: atoS [C]

Synonym: BRADO0236

Alternate gene names: 146337401

Gene position: 251919-254069 (Clockwise)

Preceding gene: 146337400

Following gene: 146337402

Centisome position: 3.38

GC content: 67.36

Gene sequence:

>2151_bases
GTGCAGACCGCACAACGCAAATCGCTGACGATGCTGCGCTGGATGATGGTCGCGTCGCTGGCGCTGCCGATCGCGTTGTT
CCTGGTCGCTGCCTACGTCTCCTACGGTGCGACCACCGACGAAGCCGACCGCGAGATCCGCCGCTCGCTCGACGTCGTCC
ACGAGCATGCGCTCAAGGTGTTCGAGACTATCGAACGTAGCCTGTCCGAGATCGACGAGATCGTCCGCGATCTCTCGGAC
TCCGATATCAAGACCCGCGAGCAGGCGCTGCATGTCCGGCTCCGGCAATTGTCCGACTCGCTGCCGCAGATGAAGTCGGC
CTGGGTGTTCGACGCCAACGGCCGGCCGCTGGTTAACAGCCTGATCTACCCGGCGCCGGAGGTGTCGTTCCTGGACCGCG
ACTACTTCAGCGCCCACGTCAAGGACAGCATCGGCACCTTCATCGGCGCGCCGTTGACGCCGCGCTCGCCCTATCCCGGC
GCGGCCTTCTTCAGCGTCAGCCGCCGCCGCCAATCCGACGACGGCAGCTTCACCGGCATCATCCAGGCGTCGGTGCTGCC
GGACTATTTCGAGCACTTCTATGCCCGCATCGGCCGCGCCCCCGGCAGCTACTTCGCCCTGAAGCGGTTCGACGGGCTGA
CGCTGGCGCGTTTTCCGGCCGCCGAGCGCAGCGCGGGTCCGGCCCCGAACGATATACCGGCGGGCGCGGCGGATACCGAG
CAGCTGGTCACCGAGACATCGCGGCGGGATGGCATCGAGCGGCGGGTCGGCTATCAGCGGCTCCCGGGCTACCCGGTCTA
TGTGGCCGCCGGCCTGGAGACCGCGACCATCCGAAACCGCTGGCTCGGGACAATGAGCCGTCACCTCATCTTCGGCATCC
CGGCGACCGCGCTGCTGGTGGTGTTTCTGACCCTCGCGCGCCGGCGCACCGAGCGCTTCTACATCGAAGCCGCCCGCCGC
CTCGAAGCCGAGGACGCGCTCAAGCACGGCCAGCGCATGGAGGCACTCGGTCAGCTGACCGGCGGCGTGGCTCACGATTT
CAACAACCTGCTGACGGTGATCCGCGCCTCGGCCGATCTGCTGCGCCGGCCGAATTTGCCGGACGAGCGTCGGCAGCGCT
ACATCGACGCCATCTCCGATACCGTGGCGCGTGCGTCCAAGCTGACGTCGCAGCTCCTGGCCTTCGCGCGAAGGCAGACC
CTGAAACCCGAAGTGTTCGACATCGGCCGCAGCGTCGTCACCCTGCGCGACATGACCAAGACGCTGGTCGGCTCGCGGAT
CGAGATCGTCACCTCGGTCCCGGACGAGCCGTGCTATGTCAACGCCGATGCCGGCCAGTTCGAGACTGCGCTGATCAACA
TGGCCGTCAATGCGCGCGACGCGATGGCCGGCCAGGGCCTGCTCAGCATCACCGTGGTGCCCGCACCGGATCTCCCGACG
CCGGTGGCGCCGCATGACCGTCCGCCGCTCGGCTATGTCGCCATCGCCGTCCAGGACACCGGTGTCGGCATTCCGCAGGA
GCAGGTCGGGCGCATCTTCGAGCCGTTCTTCACCACCAAGACAATCGGGCAGGGCACCGGCCTCGGCCTGTCGCAGGTGT
TCGGTTTCGCCAAGCAGTCCGGCGGCGAGATCGGCGTCGTCAGCGAGGTCGGCCGAGGCGCCACCTTCACTCTGTATTTG
CCGCGTGTCGCTCCGATGCAGGATCAGCATCACGCGGCTCCCGGCCACGCGGTGCCGATCACCGGCCGCGGCATGTCGGT
GCTGGTCGTCGAGGACAACATCGACGTCGGCCGGTCCGCCACCGAAGCGCTCGCCGAGCTCGGCTACCTGACCACTCTGG
TCGACAATGCCAAGGACGCGCTGGAGGAACTGATCGACGGCGCCAGCCGGTTCGATGTCGTGTTTACCGACGTGGTGATG
CCGGGGATGACGGGCCTCGAGCTCGCCGAGGAGATCCGCCGGCTCGAGCTCAACATCCCCGTCGTGCTCGCCAGCGGCTA
CAGCCATGTGCTGGCTCAGCAGGGCACCAATGGATTCGAGCTGCTGCGCAAGCCGTACTCGATCGAGGAATTGTCGCGCG
TGCTTCACAAGGTCGTGCCGGTGCCGCTGTATGGCGCCCCGCCGGTGGCGCCGAACTCGGAGGTCCGCTGA

Upstream 100 bases:

>100_bases
ATATCATTGCGCCCGGGCCCGTCGGAAGTTCCGGGCGCAGCTGATTTTGTAGCTGACGCCGATTGCGATAAGCTCTCAGC
CTTCTGGGGCCGGAGCGACC

Downstream 100 bases:

>100_bases
GCGCGGCGGCCAGCGGAACCCGGATGCGGAACCTTCTATGTGGGTTCCGGTTATCGCGACATGGGACAGATCCAGGACAT
CGAGCGGCCCGTCACGTCGG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MQTAQRKSLTMLRWMMVASLALPIALFLVAAYVSYGATTDEADREIRRSLDVVHEHALKVFETIERSLSEIDEIVRDLSD
SDIKTREQALHVRLRQLSDSLPQMKSAWVFDANGRPLVNSLIYPAPEVSFLDRDYFSAHVKDSIGTFIGAPLTPRSPYPG
AAFFSVSRRRQSDDGSFTGIIQASVLPDYFEHFYARIGRAPGSYFALKRFDGLTLARFPAAERSAGPAPNDIPAGAADTE
QLVTETSRRDGIERRVGYQRLPGYPVYVAAGLETATIRNRWLGTMSRHLIFGIPATALLVVFLTLARRRTERFYIEAARR
LEAEDALKHGQRMEALGQLTGGVAHDFNNLLTVIRASADLLRRPNLPDERRQRYIDAISDTVARASKLTSQLLAFARRQT
LKPEVFDIGRSVVTLRDMTKTLVGSRIEIVTSVPDEPCYVNADAGQFETALINMAVNARDAMAGQGLLSITVVPAPDLPT
PVAPHDRPPLGYVAIAVQDTGVGIPQEQVGRIFEPFFTTKTIGQGTGLGLSQVFGFAKQSGGEIGVVSEVGRGATFTLYL
PRVAPMQDQHHAAPGHAVPITGRGMSVLVVEDNIDVGRSATEALAELGYLTTLVDNAKDALEELIDGASRFDVVFTDVVM
PGMTGLELAEEIRRLELNIPVVLASGYSHVLAQQGTNGFELLRKPYSIEELSRVLHKVVPVPLYGAPPVAPNSEVR

Sequences:

>Translated_716_residues
MQTAQRKSLTMLRWMMVASLALPIALFLVAAYVSYGATTDEADREIRRSLDVVHEHALKVFETIERSLSEIDEIVRDLSD
SDIKTREQALHVRLRQLSDSLPQMKSAWVFDANGRPLVNSLIYPAPEVSFLDRDYFSAHVKDSIGTFIGAPLTPRSPYPG
AAFFSVSRRRQSDDGSFTGIIQASVLPDYFEHFYARIGRAPGSYFALKRFDGLTLARFPAAERSAGPAPNDIPAGAADTE
QLVTETSRRDGIERRVGYQRLPGYPVYVAAGLETATIRNRWLGTMSRHLIFGIPATALLVVFLTLARRRTERFYIEAARR
LEAEDALKHGQRMEALGQLTGGVAHDFNNLLTVIRASADLLRRPNLPDERRQRYIDAISDTVARASKLTSQLLAFARRQT
LKPEVFDIGRSVVTLRDMTKTLVGSRIEIVTSVPDEPCYVNADAGQFETALINMAVNARDAMAGQGLLSITVVPAPDLPT
PVAPHDRPPLGYVAIAVQDTGVGIPQEQVGRIFEPFFTTKTIGQGTGLGLSQVFGFAKQSGGEIGVVSEVGRGATFTLYL
PRVAPMQDQHHAAPGHAVPITGRGMSVLVVEDNIDVGRSATEALAELGYLTTLVDNAKDALEELIDGASRFDVVFTDVVM
PGMTGLELAEEIRRLELNIPVVLASGYSHVLAQQGTNGFELLRKPYSIEELSRVLHKVVPVPLYGAPPVAPNSEVR
>Mature_716_residues
MQTAQRKSLTMLRWMMVASLALPIALFLVAAYVSYGATTDEADREIRRSLDVVHEHALKVFETIERSLSEIDEIVRDLSD
SDIKTREQALHVRLRQLSDSLPQMKSAWVFDANGRPLVNSLIYPAPEVSFLDRDYFSAHVKDSIGTFIGAPLTPRSPYPG
AAFFSVSRRRQSDDGSFTGIIQASVLPDYFEHFYARIGRAPGSYFALKRFDGLTLARFPAAERSAGPAPNDIPAGAADTE
QLVTETSRRDGIERRVGYQRLPGYPVYVAAGLETATIRNRWLGTMSRHLIFGIPATALLVVFLTLARRRTERFYIEAARR
LEAEDALKHGQRMEALGQLTGGVAHDFNNLLTVIRASADLLRRPNLPDERRQRYIDAISDTVARASKLTSQLLAFARRQT
LKPEVFDIGRSVVTLRDMTKTLVGSRIEIVTSVPDEPCYVNADAGQFETALINMAVNARDAMAGQGLLSITVVPAPDLPT
PVAPHDRPPLGYVAIAVQDTGVGIPQEQVGRIFEPFFTTKTIGQGTGLGLSQVFGFAKQSGGEIGVVSEVGRGATFTLYL
PRVAPMQDQHHAAPGHAVPITGRGMSVLVVEDNIDVGRSATEALAELGYLTTLVDNAKDALEELIDGASRFDVVFTDVVM
PGMTGLELAEEIRRLELNIPVVLASGYSHVLAQQGTNGFELLRKPYSIEELSRVLHKVVPVPLYGAPPVAPNSEVR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=31.8725099601594, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790436, Length=274, Percent_Identity=28.8321167883212, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=168, Percent_Identity=35.7142857142857, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=25.4480286738351, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=28.8389513108614, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=408, Percent_Identity=24.7549019607843, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78425; Mature: 78425

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAQRKSLTMLRWMMVASLALPIALFLVAAYVSYGATTDEADREIRRSLDVVHEHALKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FETIERSLSEIDEIVRDLSDSDIKTREQALHVRLRQLSDSLPQMKSAWVFDANGRPLVNS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
LIYPAPEVSFLDRDYFSAHVKDSIGTFIGAPLTPRSPYPGAAFFSVSRRRQSDDGSFTGI
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
IQASVLPDYFEHFYARIGRAPGSYFALKRFDGLTLARFPAAERSAGPAPNDIPAGAADTE
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHH
QLVTETSRRDGIERRVGYQRLPGYPVYVAAGLETATIRNRWLGTMSRHLIFGIPATALLV
HHHHHHHHHCCHHHHCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEECCHHHHHH
VFLTLARRRTERFYIEAARRLEAEDALKHGQRMEALGQLTGGVAHDFNNLLTVIRASADL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LRRPNLPDERRQRYIDAISDTVARASKLTSQLLAFARRQTLKPEVFDIGRSVVTLRDMTK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHH
TLVGSRIEIVTSVPDEPCYVNADAGQFETALINMAVNARDAMAGQGLLSITVVPAPDLPT
HHHCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHCCHHHHCCCCEEEEEEECCCCCCC
PVAPHDRPPLGYVAIAVQDTGVGIPQEQVGRIFEPFFTTKTIGQGTGLGLSQVFGFAKQS
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
GGEIGVVSEVGRGATFTLYLPRVAPMQDQHHAAPGHAVPITGRGMSVLVVEDNIDVGRSA
CCCEEEHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCHH
TEALAELGYLTTLVDNAKDALEELIDGASRFDVVFTDVVMPGMTGLELAEEIRRLELNIP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
VVLASGYSHVLAQQGTNGFELLRKPYSIEELSRVLHKVVPVPLYGAPPVAPNSEVR
EEEECCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTAQRKSLTMLRWMMVASLALPIALFLVAAYVSYGATTDEADREIRRSLDVVHEHALKV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FETIERSLSEIDEIVRDLSDSDIKTREQALHVRLRQLSDSLPQMKSAWVFDANGRPLVNS
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
LIYPAPEVSFLDRDYFSAHVKDSIGTFIGAPLTPRSPYPGAAFFSVSRRRQSDDGSFTGI
HCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
IQASVLPDYFEHFYARIGRAPGSYFALKRFDGLTLARFPAAERSAGPAPNDIPAGAADTE
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHH
QLVTETSRRDGIERRVGYQRLPGYPVYVAAGLETATIRNRWLGTMSRHLIFGIPATALLV
HHHHHHHHHCCHHHHCCHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHEEECCHHHHHH
VFLTLARRRTERFYIEAARRLEAEDALKHGQRMEALGQLTGGVAHDFNNLLTVIRASADL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LRRPNLPDERRQRYIDAISDTVARASKLTSQLLAFARRQTLKPEVFDIGRSVVTLRDMTK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHH
TLVGSRIEIVTSVPDEPCYVNADAGQFETALINMAVNARDAMAGQGLLSITVVPAPDLPT
HHHCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHCCHHHHCCCCEEEEEEECCCCCCC
PVAPHDRPPLGYVAIAVQDTGVGIPQEQVGRIFEPFFTTKTIGQGTGLGLSQVFGFAKQS
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
GGEIGVVSEVGRGATFTLYLPRVAPMQDQHHAAPGHAVPITGRGMSVLVVEDNIDVGRSA
CCCEEEHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCHH
TEALAELGYLTTLVDNAKDALEELIDGASRFDVVFTDVVMPGMTGLELAEEIRRLELNIP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
VVLASGYSHVLAQQGTNGFELLRKPYSIEELSRVLHKVVPVPLYGAPPVAPNSEVR
EEEECCHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA