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The map label for this gene is moeZ [H]

Identifier: 146337243

GI number: 146337243

Start: 79118

End: 79921

Strand: Reverse

Name: moeZ [H]

Synonym: BRADO0069

Alternate gene names: 146337243

Gene position: 79921-79118 (Counterclockwise)

Preceding gene: 146337246

Following gene: 146337241

Centisome position: 1.07

GC content: 67.16

Gene sequence:

>804_bases
ATGCTGAGCGACGAGGAACTGGAGCGCTACGCCCGCCATATCGTGCTGCGCGATGTCGGCGGTCCTGGTCAGGCTGCGCT
GAAGCGCGCATCGGTGCTGGTGATCGGCGCGGGCGGGCTCGGCGCACCGGCGCTGATGTATCTCGCCGCTGCCGGCGTGG
GCACGATCGGCGTGGTCGATGACGACGTGGTATCGCTGTCAAATCTGCAGCGGCAGGTCATTCACGCGACGCCTGACATC
GGCAGGCCCAAGGTCGACAGCGCCGCCGAGCGCATCAACGCGCTCAACCCGCATGTCGGCGTCGTCGCGCACCGGACGTG
GCTCAACGCCGACAACGCGCTCGATCTGATCGGCGGCTATGATCTCGTGCTCGACGGCTCCGACAATTTCGACACGCGCT
ATCTCGTCTCCGATGCCTGCTTCCTGGCCGGCAAGCCGCTGATCACGGGCGCGCTCGGCACCTTCGATGCATCGCTGACG
ACGATCCGCGCGCATGAGCGCAATGACAAGGGCGCGTTCAATCCGACCTATCGCTGCCTGTTCCCGGAGCCGCCGCCGCC
TGGCACCGTGCCCGCCTGCGCCGAAGCCGGCGTCATGGGCGCGCTCGCCGGCATGCTCGGCTCGATGATGGCGCTGGAGG
CGATCCGCGAGATCGTCGGCTTCGGCGAGGGCCTGGTCGGCCGGCTGTTGATGCTGGACGCCCGCACCATGCGCTTCGAA
ACGCTGCGCTATGGCCGCGATCCGGCGAACCCGCTGAATGGTGATGGACCTGTCATCGCGGATCTCAGTGCACATCGAAA
GTGA

Upstream 100 bases:

>100_bases
CATCTGCTTGGTCGGCCACAATCCGGCGCGGGTTCAGTGGAGAGCTGCGGTCTCCATGATCAGCCGATGGCGATGTAGCG
GCGGAAGGACGCGTGTGACG

Downstream 100 bases:

>100_bases
TGTCGTAAGCTCGCGATCTCAATTCCGTTGTCATCCCGGACAAGCTCGGCGACCCAGCGCGTCGTCGAGCGCAGATCCGG
GATCCATACGCCGCAGCAGT

Product: putative molybdopterin biosynthesis protein moeB

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLSDEELERYARHIVLRDVGGPGQAALKRASVLVIGAGGLGAPALMYLAAAGVGTIGVVDDDVVSLSNLQRQVIHATPDI
GRPKVDSAAERINALNPHVGVVAHRTWLNADNALDLIGGYDLVLDGSDNFDTRYLVSDACFLAGKPLITGALGTFDASLT
TIRAHERNDKGAFNPTYRCLFPEPPPPGTVPACAEAGVMGALAGMLGSMMALEAIREIVGFGEGLVGRLLMLDARTMRFE
TLRYGRDPANPLNGDGPVIADLSAHRK

Sequences:

>Translated_267_residues
MLSDEELERYARHIVLRDVGGPGQAALKRASVLVIGAGGLGAPALMYLAAAGVGTIGVVDDDVVSLSNLQRQVIHATPDI
GRPKVDSAAERINALNPHVGVVAHRTWLNADNALDLIGGYDLVLDGSDNFDTRYLVSDACFLAGKPLITGALGTFDASLT
TIRAHERNDKGAFNPTYRCLFPEPPPPGTVPACAEAGVMGALAGMLGSMMALEAIREIVGFGEGLVGRLLMLDARTMRFE
TLRYGRDPANPLNGDGPVIADLSAHRK
>Mature_267_residues
MLSDEELERYARHIVLRDVGGPGQAALKRASVLVIGAGGLGAPALMYLAAAGVGTIGVVDDDVVSLSNLQRQVIHATPDI
GRPKVDSAAERINALNPHVGVVAHRTWLNADNALDLIGGYDLVLDGSDNFDTRYLVSDACFLAGKPLITGALGTFDASLT
TIRAHERNDKGAFNPTYRCLFPEPPPPGTVPACAEAGVMGALAGMLGSMMALEAIREIVGFGEGLVGRLLMLDARTMRFE
TLRYGRDPANPLNGDGPVIADLSAHRK

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=238, Percent_Identity=46.218487394958, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI4885649, Length=164, Percent_Identity=31.7073170731707, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI38045942, Length=81, Percent_Identity=48.1481481481481, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI38045944, Length=81, Percent_Identity=48.1481481481481, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI23510338, Length=145, Percent_Identity=31.7241379310345, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI23510340, Length=145, Percent_Identity=31.7241379310345, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787048, Length=257, Percent_Identity=39.6887159533074, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI87082356, Length=253, Percent_Identity=37.9446640316205, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789177, Length=131, Percent_Identity=35.1145038167939, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=260, Percent_Identity=40.7692307692308, Blast_Score=208, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193203301, Length=167, Percent_Identity=27.5449101796407, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71984476, Length=185, Percent_Identity=29.1891891891892, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321903, Length=221, Percent_Identity=47.5113122171946, Blast_Score=199, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24582879, Length=262, Percent_Identity=43.8931297709924, Blast_Score=220, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24660640, Length=141, Percent_Identity=31.9148936170213, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573937, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129973, Length=109, Percent_Identity=37.6146788990826, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28136; Mature: 28136

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDEELERYARHIVLRDVGGPGQAALKRASVLVIGAGGLGAPALMYLAAAGVGTIGVVD
CCCHHHHHHHHHHEEEEECCCCCHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCEEECCC
DDVVSLSNLQRQVIHATPDIGRPKVDSAAERINALNPHVGVVAHRTWLNADNALDLIGGY
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCE
DLVLDGSDNFDTRYLVSDACFLAGKPLITGALGTFDASLTTIRAHERNDKGAFNPTYRCL
EEEECCCCCCCCEEEHHHHHHHCCCCCEECCHHHCCCCEEEEEEECCCCCCCCCCCEEEE
FPEPPPPGTVPACAEAGVMGALAGMLGSMMALEAIREIVGFGEGLVGRLLMLDARTMRFE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRYGRDPANPLNGDGPVIADLSAHRK
HHHCCCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MLSDEELERYARHIVLRDVGGPGQAALKRASVLVIGAGGLGAPALMYLAAAGVGTIGVVD
CCCHHHHHHHHHHEEEEECCCCCHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCEEECCC
DDVVSLSNLQRQVIHATPDIGRPKVDSAAERINALNPHVGVVAHRTWLNADNALDLIGGY
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCE
DLVLDGSDNFDTRYLVSDACFLAGKPLITGALGTFDASLTTIRAHERNDKGAFNPTYRCL
EEEECCCCCCCCEEEHHHHHHHCCCCCEECCHHHCCCCEEEEEEECCCCCCCCCCCEEEE
FPEPPPPGTVPACAEAGVMGALAGMLGSMMALEAIREIVGFGEGLVGRLLMLDARTMRFE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRYGRDPANPLNGDGPVIADLSAHRK
HHHCCCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]