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The map label for this gene is crp [C]

Identifier: 146337246

GI number: 146337246

Start: 82971

End: 83453

Strand: Reverse

Name: crp [C]

Synonym: BRADO0073

Alternate gene names: 146337246

Gene position: 83453-82971 (Counterclockwise)

Preceding gene: 146337247

Following gene: 146337243

Centisome position: 1.12

GC content: 64.6

Gene sequence:

>483_bases
ATGGCTGTCAGCTCGCCCGACCTGAAAGCATTTCTGCTCGCCACGCCGTTCTTTGGCGGCCTGTCGGATGCGAGCCTCGA
CCTGCTGATTTCGATGCTGGGCGTGCGCGAGTTCGAGCGCGGCGCCGTCATCGTCGCCGAGGGTGAGGCGGGCCGCTCGA
TGTTCGTCGTGCACAGCGGCACGCTGGAGGTCAGCGAGCGCCTGGAGAGCGGTGGCGCGATCCACATGTCGAGCCTGCAG
CCCGGCGATTTCTTCGGCGAAATGACCTTGCTGGAGATGCAGAACCGATCCGCCACGGTGATCGCGGAGACGCCAGCCCT
ACTGTACGAGCTCACAGCGCAACAGCTCTATGCGTTCTACAAGGCCGACATTCGCGCCTATGTCATCGTGATGCAGAACA
TCAATCGCGAGCTGTGCCGCCGCCTGCGGCGCGCGGATGCGCGGATCAAGATGCTGGAGATGCGGGAGGCGGGGGCGCGT
TAG

Upstream 100 bases:

>100_bases
CGGACGATCGACGTTCTGGTGCCCGAAGTGTCAGAGATGAGCGAACGGCGCTCCGCCCGGGTCTGCTTGTGACGGCCGGG
CTCGGGCGTATACTGCCGTT

Downstream 100 bases:

>100_bases
GCCGGCTCTTACCGCGCTTGCAGCAGGCGTATCTCGTTCGACAATCGGGTCGTGTGCTCGGTTATTTCCAAGTCGTTATG
GTTGGGCCTGTCCAGGCCAT

Product: putative cAMP-binding protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Cyclic AMP Receptor Protein; Catabolite Gene Activator; CAMP-Dependent Protein Kinase Regulatory Subunit; CAMP-Dependent Transcriptional Regulator

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MAVSSPDLKAFLLATPFFGGLSDASLDLLISMLGVREFERGAVIVAEGEAGRSMFVVHSGTLEVSERLESGGAIHMSSLQ
PGDFFGEMTLLEMQNRSATVIAETPALLYELTAQQLYAFYKADIRAYVIVMQNINRELCRRLRRADARIKMLEMREAGAR

Sequences:

>Translated_160_residues
MAVSSPDLKAFLLATPFFGGLSDASLDLLISMLGVREFERGAVIVAEGEAGRSMFVVHSGTLEVSERLESGGAIHMSSLQ
PGDFFGEMTLLEMQNRSATVIAETPALLYELTAQQLYAFYKADIRAYVIVMQNINRELCRRLRRADARIKMLEMREAGAR
>Mature_159_residues
AVSSPDLKAFLLATPFFGGLSDASLDLLISMLGVREFERGAVIVAEGEAGRSMFVVHSGTLEVSERLESGGAIHMSSLQP
GDFFGEMTLLEMQNRSATVIAETPALLYELTAQQLYAFYKADIRAYVIVMQNINRELCRRLRRADARIKMLEMREAGAR

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17694; Mature: 17563

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00888 CNMP_BINDING_1 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSSPDLKAFLLATPFFGGLSDASLDLLISMLGVREFERGAVIVAEGEAGRSMFVVHSG
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECC
TLEVSERLESGGAIHMSSLQPGDFFGEMTLLEMQNRSATVIAETPALLYELTAQQLYAFY
CHHHHHHHCCCCEEEECCCCCCCHHCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
KADIRAYVIVMQNINRELCRRLRRADARIKMLEMREAGAR
HHHHHEEEEEHHHCCHHHHHHHHHCCHHEEHHHHHCCCCC
>Mature Secondary Structure 
AVSSPDLKAFLLATPFFGGLSDASLDLLISMLGVREFERGAVIVAEGEAGRSMFVVHSG
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECC
TLEVSERLESGGAIHMSSLQPGDFFGEMTLLEMQNRSATVIAETPALLYELTAQQLYAFY
CHHHHHHHCCCCEEEECCCCCCCHHCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
KADIRAYVIVMQNINRELCRRLRRADARIKMLEMREAGAR
HHHHHEEEEEHHHCCHHHHHHHHHCCHHEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA