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The map label for this gene is resD [H]

Identifier: 146300655

GI number: 146300655

Start: 3448843

End: 3450396

Strand: Direct

Name: resD [H]

Synonym: Fjoh_2906

Alternate gene names: 146300655

Gene position: 3448843-3450396 (Clockwise)

Preceding gene: 146300632

Following gene: 146300656

Centisome position: 56.57

GC content: 31.72

Gene sequence:

>1554_bases
ATGGATAAGATAAGAATACTTTGGGTCGATGATGAGATCGATCTTTTAAAGCCACATATATTATTTCTCGAAAAAAAGAA
TTATGAAGTTACAACAAGCAACAATGGCCTTGATGCTATTGCTTTGTTTGAAGAAGAAAACTTTGACATTGTTTTTCTTG
ACGAAAATATGCCGGGAATGAGCGGTTTAGAAACACTTTCTGAAATGAAAGAAAAAAAATCAGCCATCCCGATGATTATG
ATTACCAAGAGCGAGGAAGAATATATAATGGAAGAAGCAATTGGTTCTAAAATCGCAGACTATTTGATAAAACCAGTAAA
TCCAAATCAAATTTTACTGAGTTTAAAAAAGAATCTGGATGATTCAAGACTGATTACAGAAAAAACAACATTAGATTACC
AAAAAGAATTCCGCAAAATCTCGATGGAATTAGCTATGGTTAATTCGTATGAAGACTGGGTTGAACTGTACAAAAAACTG
CTTTTCTGGGAATTGAAACTAGAAGATATTAACGATCAGGCGATGATTGAAATTCTTGAATCTCAAAAAGTTGAAGCAAA
TTCACAATTCGGGAAATATATTGAAAGAAATTACGAAGACTGGTTTGCTCCAAAAGCAGATAAACCAATTCAATCTCATA
ATTTATTTAAAGAATTAGTTGTTCCCGAAATTAAAAAGAAAGACAAACCAATCTTGTTTGTTGTAATTGATAATCTTCGT
TACGATCAATGGAAATCTTTTGAAACTGTAATTTCTAACTATTACAAATTAGAAAAAGAAGTTCCGTATTTCTCTATTCT
TCCAACTGCAACACAATATGCCAGAAATGCAATTTTCTCTGGTTTAATGCCTTTGGATATGGAAAAACAATTTCCGCAAT
ACTGGAAAAATGACGTTGAAGACGGAGGAAAAAACCTTTATGAAGCTGAATTTCTTTCGGCACAAATAAAACGTTTAGGT
TTAAATATTAAGGAAGATTATTTTAAAATCACCAATTATGCAGGCGGAAAAAAACTGGCAGAAAATTTCAAAGCCTTAAA
AGGCAATGATTTAGTGACTGTTGTTTATAATTTCGTTGATATGCTTTCGCATGCAAAAACTGAAATGGAAGTTGTAAAAG
AATTAGCTTCTGATGACAAAGCATATCGCTCACTGACTTTAAGCTGGTTTAAAAATTCTCCATTATTAGAAATTATTCAG
CAGGCACAGCTTTTAGGATTCAAATTAATCTTAACAACAGATCACGGAACAATTAATGTAAAAAATCCGTCGAAAGTTGT
GGGAGATAAAAATACAAGTCTAAATTTGCGTTACAAAACCGGACGCAGTTTAACATACGAACAAAAGGATGTTTATGTGG
TTAAAGAACCAAAAACAATTGGTTTACCGGCTATAAATATGAGCAGTTCGTTTATTTTTGCCAAAAATGATTTTTTTCTG
GCTTATGTAAACAACTACAATCATTATGTAAGTTATTATAAAAACACATATCAGCACGGCGGGATTTCGTTAGAAGAAAT
GATTATTCCGTTTTTGGTATTTAACCCTAAATAA

Upstream 100 bases:

>100_bases
TAATTCAAAATAAATTTCATTTCAGCATTCCTAATTTTATACTATTTTTAATACTTTTTAAGTTCTATACATTTAAATTG
CATTAAAATTAAAACTGTTT

Downstream 100 bases:

>100_bases
AAAAGTTTTCAGTCGCAGTTTTCAGTCTCAGTCTGAGAAGTGAAAACTGTGACTGAGACTAAAATAAATAAACATAAAAA
TGAATATCGTTTTTTCATTA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MDKIRILWVDDEIDLLKPHILFLEKKNYEVTTSNNGLDAIALFEEENFDIVFLDENMPGMSGLETLSEMKEKKSAIPMIM
ITKSEEEYIMEEAIGSKIADYLIKPVNPNQILLSLKKNLDDSRLITEKTTLDYQKEFRKISMELAMVNSYEDWVELYKKL
LFWELKLEDINDQAMIEILESQKVEANSQFGKYIERNYEDWFAPKADKPIQSHNLFKELVVPEIKKKDKPILFVVIDNLR
YDQWKSFETVISNYYKLEKEVPYFSILPTATQYARNAIFSGLMPLDMEKQFPQYWKNDVEDGGKNLYEAEFLSAQIKRLG
LNIKEDYFKITNYAGGKKLAENFKALKGNDLVTVVYNFVDMLSHAKTEMEVVKELASDDKAYRSLTLSWFKNSPLLEIIQ
QAQLLGFKLILTTDHGTINVKNPSKVVGDKNTSLNLRYKTGRSLTYEQKDVYVVKEPKTIGLPAINMSSSFIFAKNDFFL
AYVNNYNHYVSYYKNTYQHGGISLEEMIIPFLVFNPK

Sequences:

>Translated_517_residues
MDKIRILWVDDEIDLLKPHILFLEKKNYEVTTSNNGLDAIALFEEENFDIVFLDENMPGMSGLETLSEMKEKKSAIPMIM
ITKSEEEYIMEEAIGSKIADYLIKPVNPNQILLSLKKNLDDSRLITEKTTLDYQKEFRKISMELAMVNSYEDWVELYKKL
LFWELKLEDINDQAMIEILESQKVEANSQFGKYIERNYEDWFAPKADKPIQSHNLFKELVVPEIKKKDKPILFVVIDNLR
YDQWKSFETVISNYYKLEKEVPYFSILPTATQYARNAIFSGLMPLDMEKQFPQYWKNDVEDGGKNLYEAEFLSAQIKRLG
LNIKEDYFKITNYAGGKKLAENFKALKGNDLVTVVYNFVDMLSHAKTEMEVVKELASDDKAYRSLTLSWFKNSPLLEIIQ
QAQLLGFKLILTTDHGTINVKNPSKVVGDKNTSLNLRYKTGRSLTYEQKDVYVVKEPKTIGLPAINMSSSFIFAKNDFFL
AYVNNYNHYVSYYKNTYQHGGISLEEMIIPFLVFNPK
>Mature_517_residues
MDKIRILWVDDEIDLLKPHILFLEKKNYEVTTSNNGLDAIALFEEENFDIVFLDENMPGMSGLETLSEMKEKKSAIPMIM
ITKSEEEYIMEEAIGSKIADYLIKPVNPNQILLSLKKNLDDSRLITEKTTLDYQKEFRKISMELAMVNSYEDWVELYKKL
LFWELKLEDINDQAMIEILESQKVEANSQFGKYIERNYEDWFAPKADKPIQSHNLFKELVVPEIKKKDKPILFVVIDNLR
YDQWKSFETVISNYYKLEKEVPYFSILPTATQYARNAIFSGLMPLDMEKQFPQYWKNDVEDGGKNLYEAEFLSAQIKRLG
LNIKEDYFKITNYAGGKKLAENFKALKGNDLVTVVYNFVDMLSHAKTEMEVVKELASDDKAYRSLTLSWFKNSPLLEIIQ
QAQLLGFKLILTTDHGTINVKNPSKVVGDKNTSLNLRYKTGRSLTYEQKDVYVVKEPKTIGLPAINMSSSFIFAKNDFFL
AYVNNYNHYVSYYKNTYQHGGISLEEMIIPFLVFNPK

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=145, Percent_Identity=31.7241379310345, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=32.1739130434783, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 60170; Mature: 60170

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIRILWVDDEIDLLKPHILFLEKKNYEVTTSNNGLDAIALFEEENFDIVFLDENMPGM
CCCEEEEEECCCCHHCCCEEEEEEECCEEEEECCCCCEEEEEEECCCCEEEEECCCCCCC
SGLETLSEMKEKKSAIPMIMITKSEEEYIMEEAIGSKIADYLIKPVNPNQILLSLKKNLD
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
DSRLITEKTTLDYQKEFRKISMELAMVNSYEDWVELYKKLLFWELKLEDINDQAMIEILE
CCCEEEEHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
SQKVEANSQFGKYIERNYEDWFAPKADKPIQSHNLFKELVVPEIKKKDKPILFVVIDNLR
HCCCCCCHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCHHHHCCCCCEEEEEECCCC
YDQWKSFETVISNYYKLEKEVPYFSILPTATQYARNAIFSGLMPLDMEKQFPQYWKNDVE
CCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DGGKNLYEAEFLSAQIKRLGLNIKEDYFKITNYAGGKKLAENFKALKGNDLVTVVYNFVD
HCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
MLSHAKTEMEVVKELASDDKAYRSLTLSWFKNSPLLEIIQQAQLLGFKLILTTDHGTINV
HHHHHHHHHHHHHHHHCCCHHHHHEEEEHHCCCCHHHHHHHHHHCCEEEEEEECCCEEEE
KNPSKVVGDKNTSLNLRYKTGRSLTYEQKDVYVVKEPKTIGLPAINMSSSFIFAKNDFFL
CCCHHHCCCCCCEEEEEEECCCCEEEECCCEEEEECCCEECCCEECCCCCEEEEECCEEE
AYVNNYNHYVSYYKNTYQHGGISLEEMIIPFLVFNPK
EEECCCCHHHHHHHHHHHCCCCCHHHHHEEEEEECCC
>Mature Secondary Structure
MDKIRILWVDDEIDLLKPHILFLEKKNYEVTTSNNGLDAIALFEEENFDIVFLDENMPGM
CCCEEEEEECCCCHHCCCEEEEEEECCEEEEECCCCCEEEEEEECCCCEEEEECCCCCCC
SGLETLSEMKEKKSAIPMIMITKSEEEYIMEEAIGSKIADYLIKPVNPNQILLSLKKNLD
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
DSRLITEKTTLDYQKEFRKISMELAMVNSYEDWVELYKKLLFWELKLEDINDQAMIEILE
CCCEEEEHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHH
SQKVEANSQFGKYIERNYEDWFAPKADKPIQSHNLFKELVVPEIKKKDKPILFVVIDNLR
HCCCCCCHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCHHHHCCCCCEEEEEECCCC
YDQWKSFETVISNYYKLEKEVPYFSILPTATQYARNAIFSGLMPLDMEKQFPQYWKNDVE
CCHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
DGGKNLYEAEFLSAQIKRLGLNIKEDYFKITNYAGGKKLAENFKALKGNDLVTVVYNFVD
HCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
MLSHAKTEMEVVKELASDDKAYRSLTLSWFKNSPLLEIIQQAQLLGFKLILTTDHGTINV
HHHHHHHHHHHHHHHHCCCHHHHHEEEEHHCCCCHHHHHHHHHHCCEEEEEEECCCEEEE
KNPSKVVGDKNTSLNLRYKTGRSLTYEQKDVYVVKEPKTIGLPAINMSSSFIFAKNDFFL
CCCHHHCCCCCCEEEEEEECCCCEEEECCCEEEEECCCEECCCEECCCCCEEEEECCEEE
AYVNNYNHYVSYYKNTYQHGGISLEEMIIPFLVFNPK
EEECCCCHHHHHHHHHHHCCCCCHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]