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The map label for this gene is lpxD [H]

Identifier: 146300653

GI number: 146300653

Start: 3446308

End: 3447351

Strand: Reverse

Name: lpxD [H]

Synonym: Fjoh_2904

Alternate gene names: 146300653

Gene position: 3447351-3446308 (Counterclockwise)

Preceding gene: 146300654

Following gene: 146300652

Centisome position: 56.54

GC content: 34.39

Gene sequence:

>1044_bases
ATGAAATTTACAGCAGAACAAATAGCAGGAATTTTAGAAGGAGAAGTTGTTGGGAATCCCAATGCAGAAGTTTCTCGACT
TTCTAAGATAGAAGAAGGTGAGGAGGGATCTCTTACTTTTTTGGCTAATCCCAAATATATCAATTACATATATAGTACAA
AAGCAACTGTTACAATTGTTAACGACAGCTTTATTCCTGAGCAGGAAATTACTACTACTTTAATAAAAGTAGAAGATGCT
TATGCAGCATTTTCTAAACTTTTACACTTTTACAATCAGGTTAAATTAAATAAAAACGGAATCGAGCCGCAGTCATTTAT
GTCTGAGGGAACTAAATATGGAGAAAATCTATATCTGGGAAGTTTTAGTTACGTAGGGCAGAATGTCGTTTTGGGGGATA
ATGTTAAAATTTATCCTAACAGCTTTATTGGAGATAATGTAACAATAGGTGATAATGTCTTTATTTTTGCCGGCGCAAAA
ATTTATTCAGAAACTGTAATTGGAAATAATTGCACTATTCATTCAGGTACTATTATAGGTGCAGATGGTTTTGGTTTTGT
ACCAAATGAAGAAGGGGTGTACAGTAAAGTGCCACAGATTGGCAACGTTATTATTGAAGATAATGTAGATATTGGTGCAA
ATACAACAATAGACAGAGCAACTCTTGGTTCTACAATTATTAGACAAGGAGTTAAATTAGACAATCAAATTCAGGTCGCT
CACAATGTTGAAATTGGTAAAAACACAGTAATTGCAGCACAAAGCGGCGTTGCGGGTTCTACTAAAATTGGAGAAAACTG
TATGATTGGAGGGCAGGTTGGTATCGCAGGCCACTTAACTATTGGAAATAATGTGAGACTTCAGGCACAGTCTGGAGTAG
CAAGAAACATTAAAGATGACGAAGTTCTGCAGGGAACACCATCTCTTGGATATACTGATTTTAATAAATCGTATGTTCAC
TTTAAAAATCTTCCTAAGATAGTTGCCGAAGTTGAAGAAATAAAAAAACAAATAATAAACCCAAAAAATGGAAATAATGG
TTAA

Upstream 100 bases:

>100_bases
GAAATCGTTATCTAAATTGGTGACAAAATATTATATCTGTTTTCCAAAACAACTTATCTAAAATTAACATTTAAAATCTA
TTTTTTATATTTTTGTCGCG

Downstream 100 bases:

>100_bases
ACAGAAGACCATCAAAAATGAAATTTCACTAACAGGAGTTGGATTACATACTGGAAAAGAAGTTACTATGACTTTTAAAC
CTGCTCCTATTAATAATGGT

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKFTAEQIAGILEGEVVGNPNAEVSRLSKIEEGEEGSLTFLANPKYINYIYSTKATVTIVNDSFIPEQEITTTLIKVEDA
YAAFSKLLHFYNQVKLNKNGIEPQSFMSEGTKYGENLYLGSFSYVGQNVVLGDNVKIYPNSFIGDNVTIGDNVFIFAGAK
IYSETVIGNNCTIHSGTIIGADGFGFVPNEEGVYSKVPQIGNVIIEDNVDIGANTTIDRATLGSTIIRQGVKLDNQIQVA
HNVEIGKNTVIAAQSGVAGSTKIGENCMIGGQVGIAGHLTIGNNVRLQAQSGVARNIKDDEVLQGTPSLGYTDFNKSYVH
FKNLPKIVAEVEEIKKQIINPKNGNNG

Sequences:

>Translated_347_residues
MKFTAEQIAGILEGEVVGNPNAEVSRLSKIEEGEEGSLTFLANPKYINYIYSTKATVTIVNDSFIPEQEITTTLIKVEDA
YAAFSKLLHFYNQVKLNKNGIEPQSFMSEGTKYGENLYLGSFSYVGQNVVLGDNVKIYPNSFIGDNVTIGDNVFIFAGAK
IYSETVIGNNCTIHSGTIIGADGFGFVPNEEGVYSKVPQIGNVIIEDNVDIGANTTIDRATLGSTIIRQGVKLDNQIQVA
HNVEIGKNTVIAAQSGVAGSTKIGENCMIGGQVGIAGHLTIGNNVRLQAQSGVARNIKDDEVLQGTPSLGYTDFNKSYVH
FKNLPKIVAEVEEIKKQIINPKNGNNG
>Mature_347_residues
MKFTAEQIAGILEGEVVGNPNAEVSRLSKIEEGEEGSLTFLANPKYINYIYSTKATVTIVNDSFIPEQEITTTLIKVEDA
YAAFSKLLHFYNQVKLNKNGIEPQSFMSEGTKYGENLYLGSFSYVGQNVVLGDNVKIYPNSFIGDNVTIGDNVFIFAGAK
IYSETVIGNNCTIHSGTIIGADGFGFVPNEEGVYSKVPQIGNVIIEDNVDIGANTTIDRATLGSTIIRQGVKLDNQIQVA
HNVEIGKNTVIAAQSGVAGSTKIGENCMIGGQVGIAGHLTIGNNVRLQAQSGVARNIKDDEVLQGTPSLGYTDFNKSYVH
FKNLPKIVAEVEEIKKQIINPKNGNNG

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=328, Percent_Identity=34.4512195121951, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 37377; Mature: 37377

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTAEQIAGILEGEVVGNPNAEVSRLSKIEEGEEGSLTFLANPKYINYIYSTKATVTIV
CCCCHHHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCEEEEEE
NDSFIPEQEITTTLIKVEDAYAAFSKLLHFYNQVKLNKNGIEPQSFMSEGTKYGENLYLG
ECCCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCEEEEE
SFSYVGQNVVLGDNVKIYPNSFIGDNVTIGDNVFIFAGAKIYSETVIGNNCTIHSGTIIG
CHHHCCCEEEECCCEEECCCCCCCCCEEECCCEEEEECCEEEEHEEECCCEEEECCEEEC
ADGFGFVPNEEGVYSKVPQIGNVIIEDNVDIGANTTIDRATLGSTIIRQGVKLDNQIQVA
CCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
HNVEIGKNTVIAAQSGVAGSTKIGENCMIGGQVGIAGHLTIGNNVRLQAQSGVARNIKDD
EEEECCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEECCCCCCCCCCC
EVLQGTPSLGYTDFNKSYVHFKNLPKIVAEVEEIKKQIINPKNGNNG
HHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKFTAEQIAGILEGEVVGNPNAEVSRLSKIEEGEEGSLTFLANPKYINYIYSTKATVTIV
CCCCHHHHHHHHCCCEECCCCHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCEEEEEE
NDSFIPEQEITTTLIKVEDAYAAFSKLLHFYNQVKLNKNGIEPQSFMSEGTKYGENLYLG
ECCCCCCHHHEEEEEEEHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCEEEEE
SFSYVGQNVVLGDNVKIYPNSFIGDNVTIGDNVFIFAGAKIYSETVIGNNCTIHSGTIIG
CHHHCCCEEEECCCEEECCCCCCCCCEEECCCEEEEECCEEEEHEEECCCEEEECCEEEC
ADGFGFVPNEEGVYSKVPQIGNVIIEDNVDIGANTTIDRATLGSTIIRQGVKLDNQIQVA
CCCCCCCCCCCCHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
HNVEIGKNTVIAAQSGVAGSTKIGENCMIGGQVGIAGHLTIGNNVRLQAQSGVARNIKDD
EEEECCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEEECCCEEEEECCCCCCCCCCC
EVLQGTPSLGYTDFNKSYVHFKNLPKIVAEVEEIKKQIINPKNGNNG
HHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA