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The map label for this gene is msrB [H]

Identifier: 146300307

GI number: 146300307

Start: 3035662

End: 3036108

Strand: Reverse

Name: msrB [H]

Synonym: Fjoh_2552

Alternate gene names: 146300307

Gene position: 3036108-3035662 (Counterclockwise)

Preceding gene: 146300308

Following gene: 146300306

Centisome position: 49.8

GC content: 36.91

Gene sequence:

>447_bases
ATGATAAAATGGGCAGATGTAATTCATTTTACAAATAAAGGAAATCCAACTCCGGATAAAAGAGTAGAGAAAACAGAAGA
AGAATGGAAACAGCTTTTAACTCCTGAAGAATATCAGGTAACACGTTTAAAAGGAACCGAAAGATCTTTCAGCTCTGAAA
TGTGCAGTTTATTTGATCCTGGAATTTACGAATGCAAATGCTGCGGAACTGTTCTTTTTGATGCGAGTGAAAAATTTGAA
TCAGGAACAGGCTGGCCTTCTTTTACACAGCCAATTAAAGAAAATGCAATTGGTTATCATGCAGACAAATCATACGGCAT
GATACGTGTTGAAGTTGTCTGTAATGTATGCGACGCGCATTTAGGACACGTATTCCCTGATGGACCTCCTCCAACAGGTT
TACGATACTGCATAAATGCCATTTCACTATCAAAAATTAAAGAATAA

Upstream 100 bases:

>100_bases
CAGAAGGAAGAGGAATAGTATTCAGTCGCAGTCTCAGTTTTCAATAAACTGAGACTGTACTGAGACTGAAAACTGAGACT
GAAAACTAAAAAAAATAGTT

Downstream 100 bases:

>100_bases
ATTCTACAAGCGATTCCTTCAAAAAAAAGCGAATCGCTTTTTTTTAATCTTCACTGAACTAAACAATTAACAAAACAAAT
GTAAGTCGCTACTTATCAAT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MIKWADVIHFTNKGNPTPDKRVEKTEEEWKQLLTPEEYQVTRLKGTERSFSSEMCSLFDPGIYECKCCGTVLFDASEKFE
SGTGWPSFTQPIKENAIGYHADKSYGMIRVEVVCNVCDAHLGHVFPDGPPPTGLRYCINAISLSKIKE

Sequences:

>Translated_148_residues
MIKWADVIHFTNKGNPTPDKRVEKTEEEWKQLLTPEEYQVTRLKGTERSFSSEMCSLFDPGIYECKCCGTVLFDASEKFE
SGTGWPSFTQPIKENAIGYHADKSYGMIRVEVVCNVCDAHLGHVFPDGPPPTGLRYCINAISLSKIKE
>Mature_148_residues
MIKWADVIHFTNKGNPTPDKRVEKTEEEWKQLLTPEEYQVTRLKGTERSFSSEMCSLFDPGIYECKCCGTVLFDASEKFE
SGTGWPSFTQPIKENAIGYHADKSYGMIRVEVVCNVCDAHLGHVFPDGPPPTGLRYCINAISLSKIKE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=124, Percent_Identity=53.2258064516129, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI301336162, Length=124, Percent_Identity=53.2258064516129, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI73089054, Length=124, Percent_Identity=53.2258064516129, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI37620216, Length=124, Percent_Identity=53.2258064516129, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI117606353, Length=126, Percent_Identity=46.8253968253968, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=47.8991596638655, Blast_Score=123, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17553450, Length=121, Percent_Identity=46.2809917355372, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115532676, Length=121, Percent_Identity=46.2809917355372, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=148, Percent_Identity=33.1081081081081, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221378664, Length=129, Percent_Identity=42.6356589147287, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI221378662, Length=136, Percent_Identity=40.4411764705882, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=43.2, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=43.2, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=43.2, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=39.7058823529412, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=39.7058823529412, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16697; Mature: 16697

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWADVIHFTNKGNPTPDKRVEKTEEEWKQLLTPEEYQVTRLKGTERSFSSEMCSLFDP
CCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCC
GIYECKCCGTVLFDASEKFESGTGWPSFTQPIKENAIGYHADKSYGMIRVEVVCNVCDAH
CCCEEHECCCCEECCCHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
LGHVFPDGPPPTGLRYCINAISLSKIKE
HCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKWADVIHFTNKGNPTPDKRVEKTEEEWKQLLTPEEYQVTRLKGTERSFSSEMCSLFDP
CCCHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCC
GIYECKCCGTVLFDASEKFESGTGWPSFTQPIKENAIGYHADKSYGMIRVEVVCNVCDAH
CCCEEHECCCCEECCCHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
LGHVFPDGPPPTGLRYCINAISLSKIKE
HCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA