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The map label for this gene is yccK [H]

Identifier: 146300080

GI number: 146300080

Start: 2793027

End: 2794037

Strand: Reverse

Name: yccK [H]

Synonym: Fjoh_2325

Alternate gene names: 146300080

Gene position: 2794037-2793027 (Counterclockwise)

Preceding gene: 146300081

Following gene: 146300079

Centisome position: 45.83

GC content: 35.21

Gene sequence:

>1011_bases
ATGAGTACTATCAAAAAAGTTAATTTAGGAAATCAGGGACTTGTTGTTCCCAATATTGGTTTAGGCTGCATGGGAATGAG
TCAGATTGCAGGAAATGATATTTATGGTAAAGCAAACGAAACTGAATCTATAAAAACAATTCACCACTCACTCGAGCTAG
GCGGTAATTTTTTAGATACAGCAGATTTATATGGTCCGCTGGCAAATGAAAGATTAATTTCAAAAGCTATAAAAGGAAAT
CGTGATGCTTACATAATTGCTACAAAATTCGGTTTTGAGATTAATGACAATGAAGAACTTACCTGGCAGTTTAATGGCAA
AAAAGAATATGTAAAAAAAGCAGTAGAACGTTCTCTTAAAAATCTTGGAACAGATTATATCGATTTATACTACCTGCACC
GTGTTGATCCTAATACTCCAATAGAGGAAACAGTTCAGGCAATGTCTGATTTGGTAAAAGAAGGAAAGGTTGGTTATATT
GGTCTTTCTGAGGTTTCTTCTGAAACCATTAGAAAAGCGCACAACATTCACCCTCTAACGGCAGTTCAAAGTGAATATTC
CCTTTTTGAAAGAAGTATTGAAGAAGACGGAATTATAAAAACATTACAAGAGCTTCAAATTGGTGTAGTAGCTTATTCGC
CTCTGGGAAGAGGTTTTATTTCGGGAGAAATAAAACATCCGGATGACTTAGCCGAAAATGACTTTAGAAGATCAATTCCT
CGTTTTCAAGGAGAACAATTTTATAAAAACATTGAACTTTTAAATGAAATAAAACTTATCGCCGACGAAAGAAAAATTAC
TGCTTCGCAATTGGCTTTAGCATGGGTTGCTTCTAAAGGATTTTTAGCCATTCCTGGTACAAAGCGAGTAAAATATGTAG
AGCAAAATATCGAGGCCGCTCAGCTTGTCCTGACTACTGAAGAGTTGAACAGATTGGAAAACATTATTCCTCTAGGAACG
ATTACCGGAAATCGTTATGATGAATCTGGAATGAAATCTGTTAATCTATAA

Upstream 100 bases:

>100_bases
CTCATTTTGGATACAACTACACGAGATTTAGATACTTTATAAAAGTAATACTGACGGATCTTTGCTAAATCAATTTTGAT
TTAAAATTAAAACAGTAATT

Downstream 100 bases:

>100_bases
GAAATCAGAAAAAAAATCTACAGGAAAAGTTATCTTTATGACAGCTTTTCCTGTATTAAACCTAAAGCGATGAAGAAAGA
AGATCATACTCCGTATAACA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSTIKKVNLGNQGLVVPNIGLGCMGMSQIAGNDIYGKANETESIKTIHHSLELGGNFLDTADLYGPLANERLISKAIKGN
RDAYIIATKFGFEINDNEELTWQFNGKKEYVKKAVERSLKNLGTDYIDLYYLHRVDPNTPIEETVQAMSDLVKEGKVGYI
GLSEVSSETIRKAHNIHPLTAVQSEYSLFERSIEEDGIIKTLQELQIGVVAYSPLGRGFISGEIKHPDDLAENDFRRSIP
RFQGEQFYKNIELLNEIKLIADERKITASQLALAWVASKGFLAIPGTKRVKYVEQNIEAAQLVLTTEELNRLENIIPLGT
ITGNRYDESGMKSVNL

Sequences:

>Translated_336_residues
MSTIKKVNLGNQGLVVPNIGLGCMGMSQIAGNDIYGKANETESIKTIHHSLELGGNFLDTADLYGPLANERLISKAIKGN
RDAYIIATKFGFEINDNEELTWQFNGKKEYVKKAVERSLKNLGTDYIDLYYLHRVDPNTPIEETVQAMSDLVKEGKVGYI
GLSEVSSETIRKAHNIHPLTAVQSEYSLFERSIEEDGIIKTLQELQIGVVAYSPLGRGFISGEIKHPDDLAENDFRRSIP
RFQGEQFYKNIELLNEIKLIADERKITASQLALAWVASKGFLAIPGTKRVKYVEQNIEAAQLVLTTEELNRLENIIPLGT
ITGNRYDESGMKSVNL
>Mature_335_residues
STIKKVNLGNQGLVVPNIGLGCMGMSQIAGNDIYGKANETESIKTIHHSLELGGNFLDTADLYGPLANERLISKAIKGNR
DAYIIATKFGFEINDNEELTWQFNGKKEYVKKAVERSLKNLGTDYIDLYYLHRVDPNTPIEETVQAMSDLVKEGKVGYIG
LSEVSSETIRKAHNIHPLTAVQSEYSLFERSIEEDGIIKTLQELQIGVVAYSPLGRGFISGEIKHPDDLAENDFRRSIPR
FQGEQFYKNIELLNEIKLIADERKITASQLALAWVASKGFLAIPGTKRVKYVEQNIEAAQLVLTTEELNRLENIIPLGTI
TGNRYDESGMKSVNL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=335, Percent_Identity=28.3582089552239, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI27436966, Length=331, Percent_Identity=28.3987915407855, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436969, Length=290, Percent_Identity=27.9310344827586, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4504825, Length=290, Percent_Identity=27.9310344827586, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI27436962, Length=331, Percent_Identity=28.3987915407855, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436971, Length=292, Percent_Identity=28.0821917808219, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI223718702, Length=283, Percent_Identity=27.9151943462898, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI41327764, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI41152114, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=29.7297297297297, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=29.1925465838509, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=28.8025889967638, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788081, Length=306, Percent_Identity=28.7581699346405, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI48994888, Length=318, Percent_Identity=25.1572327044025, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=25.2906976744186, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325384, Length=319, Percent_Identity=30.7210031347962, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=28.2352941176471, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=27.0903010033445, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=307, Percent_Identity=27.0358306188925, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=27.1653543307087, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=308, Percent_Identity=26.6233766233766, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320079, Length=206, Percent_Identity=27.6699029126214, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24646155, Length=281, Percent_Identity=27.4021352313167, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=224, Percent_Identity=28.125, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=22.6470588235294, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=22.6470588235294, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24663317, Length=350, Percent_Identity=25.4285714285714, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37481; Mature: 37350

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIKKVNLGNQGLVVPNIGLGCMGMSQIAGNDIYGKANETESIKTIHHSLELGGNFLDT
CCCCEECCCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
ADLYGPLANERLISKAIKGNRDAYIIATKFGFEINDNEELTWQFNGKKEYVKKAVERSLK
HHHHCCHHHHHHHHHHHCCCCCEEEEEEEECEEECCCCEEEEEECCHHHHHHHHHHHHHH
NLGTDYIDLYYLHRVDPNTPIEETVQAMSDLVKEGKVGYIGLSEVSSETIRKAHNIHPLT
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCHH
AVQSEYSLFERSIEEDGIIKTLQELQIGVVAYSPLGRGFISGEIKHPDDLAENDFRRSIP
HHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
RFQGEQFYKNIELLNEIKLIADERKITASQLALAWVASKGFLAIPGTKRVKYVEQNIEAA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCCCHH
QLVLTTEELNRLENIIPLGTITGNRYDESGMKSVNL
HEEEEHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STIKKVNLGNQGLVVPNIGLGCMGMSQIAGNDIYGKANETESIKTIHHSLELGGNFLDT
CCCEECCCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCH
ADLYGPLANERLISKAIKGNRDAYIIATKFGFEINDNEELTWQFNGKKEYVKKAVERSLK
HHHHCCHHHHHHHHHHHCCCCCEEEEEEEECEEECCCCEEEEEECCHHHHHHHHHHHHHH
NLGTDYIDLYYLHRVDPNTPIEETVQAMSDLVKEGKVGYIGLSEVSSETIRKAHNIHPLT
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCHH
AVQSEYSLFERSIEEDGIIKTLQELQIGVVAYSPLGRGFISGEIKHPDDLAENDFRRSIP
HHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
RFQGEQFYKNIELLNEIKLIADERKITASQLALAWVASKGFLAIPGTKRVKYVEQNIEAA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHCCCHH
QLVLTTEELNRLENIIPLGTITGNRYDESGMKSVNL
HEEEEHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]