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The map label for this gene is ycjZ [C]

Identifier: 146284551

GI number: 146284551

Start: 37754

End: 38581

Strand: Reverse

Name: ycjZ [C]

Synonym: Ent638_4225

Alternate gene names: 146284551

Gene position: 38581-37754 (Counterclockwise)

Preceding gene: 146284555

Following gene: 146284549

Centisome position: 24.46

GC content: 50.12

Gene sequence:

>828_bases
ATGCGCCGTAAAAATGTGAACGATTATCAAGCTTTTATCGCAGTTGCCCGTGAAAAAAGTTTCACAAAAGCGGCCGCTCA
GTTAGGTGTCTCGCAGTCGGCACTGAGCTACACGGTAAGGACTCTTGAAGCAGATCTTGGCCTTCGTCTTCTTACACGTA
CCACGCGTAGCGTTTCTGTGACAGAAGCTGGCGAGCGGCTACTTTCCCGTGTAGGACCCCATTTTGACGAAATTGAAAGT
GAGATCGCCGCACTCAGCGGGTTGAGAGAAAAACCAGCCGGTACTGTGCGTATTACTGCCGTTGAACATGCAGCCGATAC
AATTCTCTGGCCGAAACTCGTCCCGGTGATGCTTGAGTATCCCGATATCAACATTGAAATTATCAGCGAGTACGGACTCA
AAGATATTGTCGCTGAGCGTTATGATGCTGGCGTGCGGTTGGGCGAACAGGTCGATAAGGATATGGTTTCCCTGCCGCTT
GCCAGGGACTTCCGTTTTGCAGTGGTTGGAGCGCCCTCTTATTTCATGGGGAAGGCATTTCCGGGAACGCCTCGTGATTT
AAACGACCATAGTTGTATCAGATTACGCCTGCCCACTCATGGAGGATTCTATACCTGGGAGTTTCGCAAGGATGAGACTG
AAATTAAGGTCCGTATTGATGGACGAGCGACTTTCAGCACAATAAATATGATGAGGCAGGCCGCCCTTGATGGGCTGGGA
CTTGCTTATCTGCCGCTAGATACTGTGGAGAATTATCTTGAAAACGGGATGTTAGTCCAGGTGCTGACAGACTGGTGTCC
ACCGTGTATGAACCGGGCACATGGGTAA

Upstream 100 bases:

>100_bases
CGTGGATGAGGAACGTTGGATCGTTACCAATAGACAAACCTCCACGTCAGGAATTATTTTATAAGTAAGAAATATTAATC
CAAAAGAACCTGGTCAATAA

Downstream 100 bases:

>100_bases
CAGGTTATAACGGTACGGTAAACAGCTGACGGAGGTTTGCCGTGCCCTGGACTGAGACTGTTACCATGCAACGTTTGCAG
TTTGTCGCGGCCTGCCTTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRRKNVNDYQAFIAVAREKSFTKAAAQLGVSQSALSYTVRTLEADLGLRLLTRTTRSVSVTEAGERLLSRVGPHFDEIES
EIAALSGLREKPAGTVRITAVEHAADTILWPKLVPVMLEYPDINIEIISEYGLKDIVAERYDAGVRLGEQVDKDMVSLPL
ARDFRFAVVGAPSYFMGKAFPGTPRDLNDHSCIRLRLPTHGGFYTWEFRKDETEIKVRIDGRATFSTINMMRQAALDGLG
LAYLPLDTVENYLENGMLVQVLTDWCPPCMNRAHG

Sequences:

>Translated_275_residues
MRRKNVNDYQAFIAVAREKSFTKAAAQLGVSQSALSYTVRTLEADLGLRLLTRTTRSVSVTEAGERLLSRVGPHFDEIES
EIAALSGLREKPAGTVRITAVEHAADTILWPKLVPVMLEYPDINIEIISEYGLKDIVAERYDAGVRLGEQVDKDMVSLPL
ARDFRFAVVGAPSYFMGKAFPGTPRDLNDHSCIRLRLPTHGGFYTWEFRKDETEIKVRIDGRATFSTINMMRQAALDGLG
LAYLPLDTVENYLENGMLVQVLTDWCPPCMNRAHG
>Mature_275_residues
MRRKNVNDYQAFIAVAREKSFTKAAAQLGVSQSALSYTVRTLEADLGLRLLTRTTRSVSVTEAGERLLSRVGPHFDEIES
EIAALSGLREKPAGTVRITAVEHAADTILWPKLVPVMLEYPDINIEIISEYGLKDIVAERYDAGVRLGEQVDKDMVSLPL
ARDFRFAVVGAPSYFMGKAFPGTPRDLNDHSCIRLRLPTHGGFYTWEFRKDETEIKVRIDGRATFSTINMMRQAALDGLG
LAYLPLDTVENYLENGMLVQVLTDWCPPCMNRAHG

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=267, Percent_Identity=48.314606741573, Blast_Score=262, Evalue=2e-71,
Organism=Escherichia coli, GI1787128, Length=263, Percent_Identity=39.9239543726236, Blast_Score=197, Evalue=4e-52,
Organism=Escherichia coli, GI1786401, Length=257, Percent_Identity=29.1828793774319, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI87081978, Length=264, Percent_Identity=28.4090909090909, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789440, Length=261, Percent_Identity=24.5210727969349, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789639, Length=249, Percent_Identity=30.1204819277108, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI145693193, Length=267, Percent_Identity=26.9662921348315, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=26.2548262548263, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=35, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786448, Length=262, Percent_Identity=25.1908396946565, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788706, Length=280, Percent_Identity=24.6428571428571, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI157672245, Length=152, Percent_Identity=28.2894736842105, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI145693105, Length=164, Percent_Identity=23.1707317073171, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=87, Percent_Identity=40.2298850574713, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30709; Mature: 30709

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKNVNDYQAFIAVAREKSFTKAAAQLGVSQSALSYTVRTLEADLGLRLLTRTTRSVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHCCCCEEH
TEAGERLLSRVGPHFDEIESEIAALSGLREKPAGTVRITAVEHAADTILWPKLVPVMLEY
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHEEEC
PDINIEIISEYGLKDIVAERYDAGVRLGEQVDKDMVSLPLARDFRFAVVGAPSYFMGKAF
CCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCC
PGTPRDLNDHSCIRLRLPTHGGFYTWEFRKDETEIKVRIDGRATFSTINMMRQAALDGLG
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
LAYLPLDTVENYLENGMLVQVLTDWCPPCMNRAHG
EEEECHHHHHHHHHCCEEEEHHHHCCCHHHHCCCC
>Mature Secondary Structure
MRRKNVNDYQAFIAVAREKSFTKAAAQLGVSQSALSYTVRTLEADLGLRLLTRTTRSVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHEEHHCCCCEEH
TEAGERLLSRVGPHFDEIESEIAALSGLREKPAGTVRITAVEHAADTILWPKLVPVMLEY
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHEEEC
PDINIEIISEYGLKDIVAERYDAGVRLGEQVDKDMVSLPLARDFRFAVVGAPSYFMGKAF
CCCCEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCC
PGTPRDLNDHSCIRLRLPTHGGFYTWEFRKDETEIKVRIDGRATFSTINMMRQAALDGLG
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCC
LAYLPLDTVENYLENGMLVQVLTDWCPPCMNRAHG
EEEECHHHHHHHHHCCEEEEHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]