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The map label for this gene is xerD [H]

Identifier: 146284555

GI number: 146284555

Start: 39764

End: 40753

Strand: Reverse

Name: xerD [H]

Synonym: Ent638_4229

Alternate gene names: 146284555

Gene position: 40753-39764 (Counterclockwise)

Preceding gene: 146284556

Following gene: 146284551

Centisome position: 25.83

GC content: 64.14

Gene sequence:

>990_bases
ATGATCCTGATGCCGCAAGACGATCCGGCGCTGAACGTGATCCCGGCGGGCCTTTCCCCGGAAGATGATTTTCTGCCGGT
GCTGGCGGGCGGCGAACTGCCGCTCAGTCCCGCCCGGGCCTACCTGCTTTCCCTGAATTCCCCCCGGAGCCGGCAGACCA
TGGCGTCGTTCCTCAACATTGTCGCCGGCATGCTCGGCGCCGCTTCCCTCGAGACCTGCAGCTGGGGCAGCCTGCGACGG
CATCATGTGATGGGAGTCACCGAACTGCTGCGCGACACCGGCCGGGCCACGGCGACGGTCAACACCTACCTCTCGGCGCT
GAAGGGCGTGGCGAAGGAAGCCTGGATGCTGAAGCTGATGGACGTTGAGAGCTTCCAGCACATCCGGGCGGTACGTAACC
TACGGGGCAGCCGGCTTCCCCGGGGGCGGGCCCTCCCGGCAGAGGAGATCGGAAAACTTTTTGCCGTGTGTGAGGCGGAC
GCCACCTATCTTGGGGTGCGGGATGCGGCCCTGCTGGGTGTCATTCTCGGCTGCGGACTGCGCCGTTCTGAGACGGTGGG
ACTCAGTCTGAGTGACGTTGTCACACATGAGCGGGCGCTTAGGGTGCTCGGCAAGGGGAACAAGGAGCGGCTGGCGTACA
TGCCGGCCGGAACCTGGCAGCGGCTGCAGACGTGGATCGACCAGGTGCGCGGCGAAGCGGCAGGGCCTCTGTTCACCCGT
ATCCGGCGCTTCGATACCCTGACAAATGACCGGCTGACCGATCAGGCGGTGTACCATATTCTGCAGATGCGCCAGCGGCA
GGCGCAGATTGAGCGATGTGCCCCGCATGATTTACGGCGCACCTTTGCCACCGCGATGCTGGACAATGGTGAGGATTTGA
TCACGGTAAAGGATGCTATGGGGCATGCCAGCGTCACCACCACCCAGCAGTACGACCGGCGTGGCGAGGAACGTCTGCGT
CAGGCACGTGACCGTCTGAACCTGACTTAA

Upstream 100 bases:

>100_bases
TTTGAAAAAGTAGACTCTCTGCGATAGGATTGTTCAGCACAAGTATCCCCGATTTTTCACCCAGCGCGCCGGCGATTTTC
CGGCACGGACGGAGCCTGAC

Downstream 100 bases:

>100_bases
CATCTGATTAAGTTAACAAGATGCTAAGTGAGTCCCGGACATTTCTTTTCATGATTTAAACCCTGTAACAGCTTATGGAT
GAGCAAGTGGGGTAGTCTGG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MILMPQDDPALNVIPAGLSPEDDFLPVLAGGELPLSPARAYLLSLNSPRSRQTMASFLNIVAGMLGAASLETCSWGSLRR
HHVMGVTELLRDTGRATATVNTYLSALKGVAKEAWMLKLMDVESFQHIRAVRNLRGSRLPRGRALPAEEIGKLFAVCEAD
ATYLGVRDAALLGVILGCGLRRSETVGLSLSDVVTHERALRVLGKGNKERLAYMPAGTWQRLQTWIDQVRGEAAGPLFTR
IRRFDTLTNDRLTDQAVYHILQMRQRQAQIERCAPHDLRRTFATAMLDNGEDLITVKDAMGHASVTTTQQYDRRGEERLR
QARDRLNLT

Sequences:

>Translated_329_residues
MILMPQDDPALNVIPAGLSPEDDFLPVLAGGELPLSPARAYLLSLNSPRSRQTMASFLNIVAGMLGAASLETCSWGSLRR
HHVMGVTELLRDTGRATATVNTYLSALKGVAKEAWMLKLMDVESFQHIRAVRNLRGSRLPRGRALPAEEIGKLFAVCEAD
ATYLGVRDAALLGVILGCGLRRSETVGLSLSDVVTHERALRVLGKGNKERLAYMPAGTWQRLQTWIDQVRGEAAGPLFTR
IRRFDTLTNDRLTDQAVYHILQMRQRQAQIERCAPHDLRRTFATAMLDNGEDLITVKDAMGHASVTTTQQYDRRGEERLR
QARDRLNLT
>Mature_329_residues
MILMPQDDPALNVIPAGLSPEDDFLPVLAGGELPLSPARAYLLSLNSPRSRQTMASFLNIVAGMLGAASLETCSWGSLRR
HHVMGVTELLRDTGRATATVNTYLSALKGVAKEAWMLKLMDVESFQHIRAVRNLRGSRLPRGRALPAEEIGKLFAVCEAD
ATYLGVRDAALLGVILGCGLRRSETVGLSLSDVVTHERALRVLGKGNKERLAYMPAGTWQRLQTWIDQVRGEAAGPLFTR
IRRFDTLTNDRLTDQAVYHILQMRQRQAQIERCAPHDLRRTFATAMLDNGEDLITVKDAMGHASVTTTQQYDRRGEERLR
QARDRLNLT

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=191, Percent_Identity=35.6020942408377, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790244, Length=276, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36526; Mature: 36526

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMPQDDPALNVIPAGLSPEDDFLPVLAGGELPLSPARAYLLSLNSPRSRQTMASFLNI
CEECCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCCHHHHHHHHHHH
VAGMLGAASLETCSWGSLRRHHVMGVTELLRDTGRATATVNTYLSALKGVAKEAWMLKLM
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DVESFQHIRAVRNLRGSRLPRGRALPAEEIGKLFAVCEADATYLGVRDAALLGVILGCGL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHCCC
RRSETVGLSLSDVVTHERALRVLGKGNKERLAYMPAGTWQRLQTWIDQVRGEAAGPLFTR
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHH
IRRFDTLTNDRLTDQAVYHILQMRQRQAQIERCAPHDLRRTFATAMLDNGEDLITVKDAM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEHHHC
GHASVTTTQQYDRRGEERLRQARDRLNLT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILMPQDDPALNVIPAGLSPEDDFLPVLAGGELPLSPARAYLLSLNSPRSRQTMASFLNI
CEECCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCHHHHHHEECCCCCHHHHHHHHHHH
VAGMLGAASLETCSWGSLRRHHVMGVTELLRDTGRATATVNTYLSALKGVAKEAWMLKLM
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DVESFQHIRAVRNLRGSRLPRGRALPAEEIGKLFAVCEADATYLGVRDAALLGVILGCGL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHCCC
RRSETVGLSLSDVVTHERALRVLGKGNKERLAYMPAGTWQRLQTWIDQVRGEAAGPLFTR
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCHHHHH
IRRFDTLTNDRLTDQAVYHILQMRQRQAQIERCAPHDLRRTFATAMLDNGEDLITVKDAM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEHHHC
GHASVTTTQQYDRRGEERLRQARDRLNLT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]