| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is thiE [H]
Identifier: 145296002
GI number: 145296002
Start: 2114314
End: 2114979
Strand: Direct
Name: thiE [H]
Synonym: cgR_1926
Alternate gene names: 145296002
Gene position: 2114314-2114979 (Clockwise)
Preceding gene: 145296000
Following gene: 145296003
Centisome position: 63.8
GC content: 56.31
Gene sequence:
>666_bases GTGTTTGAAAATCGTTTTGACCTGCGTTGTTATGTTGTGACTGGCGCGGGCTCGGTGGATGAGGTTGTACACACTGCGTC TGCCGCGGCTCGTGGTGGCGCGGGTGTGGTGCAGGTGCGTTCAAAGCCTATTTCGCCAGAAGCGATGAGGGAGTTGGCAT CAAAGGTTGCGCTTGAGGTTGCGCGGTGCAGCCCAACAACGAGGGTGCTTATCGACGACCACCTCCACGTTGCTTCTTCC TTAATGCGCGAAGGACTCCCGATTCATGGTGTGCATCTTGGGCAGGATGATGTGTCGGTGCTTGAGGCTCGTGAGTTGTT GGGACCTGAGGCGATCATTGGGTTGACTACTGGAACCCTAGAACTTGTGGCGGCGGCGAATGAGCTGTCCGATGTGTTGG ATTACATCGGTGCTGGGCCGTTTCGGAAGACTCCCACCAAGGATTCAGGTCGGCCACCGATTGGCCTTGCGGGTTATCCC CCTTTGGTGGAATTGTCCAAGGTGCCGATCGTTGCGATTGGTGATGTCACCCCTGCCGATGTGCGCGCTCTCAGCGCAAC CGGTGTGGCTGGCGTTGCCATGGTGCGGGCTTTTTCTGAATCTGATGATCCACAGCAGGTCGCTGAAAATGTGGTGGCCA ACTTTGAATTAGGAAGGCTCTCATGA
Upstream 100 bases:
>100_bases GTGCCCAATGCATTGGGCTGAGATTGCGCGCTGTTGCTGCGCGGGACCGTTCGAACCTGTCTGGTTAACACCAGCGAAGG AAGCGAGGATTGATTGTCCC
Downstream 100 bases:
>100_bases AAAAGCATGCGATTATTATCGGCGGCGGAATCATTGGGTTGACCACCTGCTTTGAATTCCAGGAGGCTGGTTACCAAGTC ACGTTGATTGATCCTGACCC
Product: thiamine-phosphate pyrophosphorylase
Products: NA
Alternate protein names: TMP pyrophosphorylase; TMP-PPase; Thiamine-phosphate synthase [H]
Number of amino acids: Translated: 221; Mature: 221
Protein sequence:
>221_residues MFENRFDLRCYVVTGAGSVDEVVHTASAAARGGAGVVQVRSKPISPEAMRELASKVALEVARCSPTTRVLIDDHLHVASS LMREGLPIHGVHLGQDDVSVLEARELLGPEAIIGLTTGTLELVAAANELSDVLDYIGAGPFRKTPTKDSGRPPIGLAGYP PLVELSKVPIVAIGDVTPADVRALSATGVAGVAMVRAFSESDDPQQVAENVVANFELGRLS
Sequences:
>Translated_221_residues MFENRFDLRCYVVTGAGSVDEVVHTASAAARGGAGVVQVRSKPISPEAMRELASKVALEVARCSPTTRVLIDDHLHVASS LMREGLPIHGVHLGQDDVSVLEARELLGPEAIIGLTTGTLELVAAANELSDVLDYIGAGPFRKTPTKDSGRPPIGLAGYP PLVELSKVPIVAIGDVTPADVRALSATGVAGVAMVRAFSESDDPQQVAENVVANFELGRLS >Mature_221_residues MFENRFDLRCYVVTGAGSVDEVVHTASAAARGGAGVVQVRSKPISPEAMRELASKVALEVARCSPTTRVLIDDHLHVASS LMREGLPIHGVHLGQDDVSVLEARELLGPEAIIGLTTGTLELVAAANELSDVLDYIGAGPFRKTPTKDSGRPPIGLAGYP PLVELSKVPIVAIGDVTPADVRALSATGVAGVAMVRAFSESDDPQQVAENVVANFELGRLS
Specific function: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) [H]
COG id: COG0352
COG function: function code H; Thiamine monophosphate synthase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TMP-PPase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013785 - InterPro: IPR022998 - InterPro: IPR003733 [H]
Pfam domain/function: PF02581 TMP-TENI [H]
EC number: =2.5.1.3 [H]
Molecular weight: Translated: 23099; Mature: 23099
Theoretical pI: Translated: 4.79; Mature: 4.79
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFENRFDLRCYVVTGAGSVDEVVHTASAAARGGAGVVQVRSKPISPEAMRELASKVALEV CCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHH ARCSPTTRVLIDDHLHVASSLMREGLPIHGVHLGQDDVSVLEARELLGPEAIIGLTTGTL HHCCCCEEEEEECHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCHH ELVAAANELSDVLDYIGAGPFRKTPTKDSGRPPIGLAGYPPLVELSKVPIVAIGDVTPAD HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH VRALSATGVAGVAMVRAFSESDDPQQVAENVVANFELGRLS HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC >Mature Secondary Structure MFENRFDLRCYVVTGAGSVDEVVHTASAAARGGAGVVQVRSKPISPEAMRELASKVALEV CCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHH ARCSPTTRVLIDDHLHVASSLMREGLPIHGVHLGQDDVSVLEARELLGPEAIIGLTTGTL HHCCCCEEEEEECHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCHH ELVAAANELSDVLDYIGAGPFRKTPTKDSGRPPIGLAGYPPLVELSKVPIVAIGDVTPAD HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHH VRALSATGVAGVAMVRAFSESDDPQQVAENVVANFELGRLS HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12840036 [H]