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The map label for this gene is paaE [H]

Identifier: 145294703

GI number: 145294703

Start: 708413

End: 709567

Strand: Direct

Name: paaE [H]

Synonym: cgR_0651

Alternate gene names: 145294703

Gene position: 708413-709567 (Clockwise)

Preceding gene: 145294702

Following gene: 145294704

Centisome position: 21.38

GC content: 53.16

Gene sequence:

>1155_bases
ATGACTTCTGTAATTAAGAAAAAAGCGAAATTCAACACTCTCTCAGTTTCAGGAGTTAAAAAGCTCACCGACGATTCCGT
CGAGGTCAGCTTCGATGTTCCTGAAGAACTTCAGGATGATTACGATTACATCCCCGGCCAGTACGTTGCTCTACGAGCCA
CCGTGGATGGGGAGGAACTCCGACGTTCCTATTCAATCTGCGATATCCCCAACAAGGGCACCATTCGCGTAGGTATTAAG
AAAGACCTGGGCGGCAAGTTCTCCACTTGGGCAAATGAAGAACTCCAGCTCGGCGATGTTATCGATGTGATGAACCCCCA
AGGCGCATTCACCTCCAAGATTCACGTCACCAGCCTCAATGATGCGCAAAACTTGGTTGATTCGGAATTGGGGCAGGTAG
AAAACCCTAACTTTGTTGCCATTGCCGCAGGCTCGGGCATCACCCCAATCATGTCCATTGCGCAGGCCGTGCTCAAATCC
TTGCCCAAGGCGACTTTCCAGCTGGTGTACTCCAACAAGGGTGGTGCAGATGTCATGTTCGCCGACAAAATCGGCGATCT
GAAAGACAAATACCCGGCACGCTTTGCGGTCCACCATGTGCTCACCCGCGAACAACGCGTCAATCCGCTCTTCTCCGGGC
GCATTGACGACGAAAAGATGGAGCTTCTACTCGATCAAGTGCTCCGCCCAGACCTGGTCGATGAATGGTTCCTCTGCGGA
CCTTTCGAATTGGTTCAGATGTGCCGCGACTCCCTAAAAGAGCGCGACATCGATGAAAAGCGTATCCGCTTCGAGCTCTT
CTCCACTGGCGATCCTAAGAGCGCACCTGGTGGCAACGCCGGACGCCCTGTTATTGCTGATCCCAAGGGCAAGAACATCT
CCATCCAATTCCAACTGGATGGATTGTCCGGCACCATCGAATCCCCAGTATCCGCGAAAGAGACCGTACTCAACGCAGCA
CTTCGTGCCCGCCCAGATGTACCTTTCGCGTGTGCCGGCGGAGTCTGCGGAACCTGTCGCGCAAAGGTCGTTGAAGGTGA
CTACGAGATGGATGAAAACTACGCACTCGAGCCTGATGAAGTTGCAGCTGGTTACGTGCTGACCTGCCAAACCCGACCAA
CTGGTGATTGCATCACTGTTGACTACGACGCGTAA

Upstream 100 bases:

>100_bases
CCAACACCAAATTAATTAGCCAGTTCGGTTCAACCTCTTGCAAATCTCTTCATACCTGCAAGGACTGCTTTGAGCCTTTC
GATTACTTCAAGGTGCACTA

Downstream 100 bases:

>100_bases
AGGACAAGGTCAGTGATCGATCTTAATATCCACCGCATTGATGAGCACGCAAGTTATGCCGAAGTAGTGCTCAACGATCC
ATCAACTCTCAACGCCATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTSVIKKKAKFNTLSVSGVKKLTDDSVEVSFDVPEELQDDYDYIPGQYVALRATVDGEELRRSYSICDIPNKGTIRVGIK
KDLGGKFSTWANEELQLGDVIDVMNPQGAFTSKIHVTSLNDAQNLVDSELGQVENPNFVAIAAGSGITPIMSIAQAVLKS
LPKATFQLVYSNKGGADVMFADKIGDLKDKYPARFAVHHVLTREQRVNPLFSGRIDDEKMELLLDQVLRPDLVDEWFLCG
PFELVQMCRDSLKERDIDEKRIRFELFSTGDPKSAPGGNAGRPVIADPKGKNISIQFQLDGLSGTIESPVSAKETVLNAA
LRARPDVPFACAGGVCGTCRAKVVEGDYEMDENYALEPDEVAAGYVLTCQTRPTGDCITVDYDA

Sequences:

>Translated_384_residues
MTSVIKKKAKFNTLSVSGVKKLTDDSVEVSFDVPEELQDDYDYIPGQYVALRATVDGEELRRSYSICDIPNKGTIRVGIK
KDLGGKFSTWANEELQLGDVIDVMNPQGAFTSKIHVTSLNDAQNLVDSELGQVENPNFVAIAAGSGITPIMSIAQAVLKS
LPKATFQLVYSNKGGADVMFADKIGDLKDKYPARFAVHHVLTREQRVNPLFSGRIDDEKMELLLDQVLRPDLVDEWFLCG
PFELVQMCRDSLKERDIDEKRIRFELFSTGDPKSAPGGNAGRPVIADPKGKNISIQFQLDGLSGTIESPVSAKETVLNAA
LRARPDVPFACAGGVCGTCRAKVVEGDYEMDENYALEPDEVAAGYVLTCQTRPTGDCITVDYDA
>Mature_383_residues
TSVIKKKAKFNTLSVSGVKKLTDDSVEVSFDVPEELQDDYDYIPGQYVALRATVDGEELRRSYSICDIPNKGTIRVGIKK
DLGGKFSTWANEELQLGDVIDVMNPQGAFTSKIHVTSLNDAQNLVDSELGQVENPNFVAIAAGSGITPIMSIAQAVLKSL
PKATFQLVYSNKGGADVMFADKIGDLKDKYPARFAVHHVLTREQRVNPLFSGRIDDEKMELLLDQVLRPDLVDEWFLCGP
FELVQMCRDSLKERDIDEKRIRFELFSTGDPKSAPGGNAGRPVIADPKGKNISIQFQLDGLSGTIESPVSAKETVLNAAL
RARPDVPFACAGGVCGTCRAKVVEGDYEMDENYALEPDEVAAGYVLTCQTRPTGDCITVDYDA

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI284448553, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI6552328, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI193794826, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4503327, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI284448551, Length=215, Percent_Identity=26.046511627907, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787658, Length=374, Percent_Identity=38.5026737967914, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1787098, Length=362, Percent_Identity=26.7955801104972, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788903, Length=230, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563928, Length=276, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323552, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 41997; Mature: 41866

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVIKKKAKFNTLSVSGVKKLTDDSVEVSFDVPEELQDDYDYIPGQYVALRATVDGEEL
CCHHHHHHHCCCEEEECCHHHCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCHHHH
RRSYSICDIPNKGTIRVGIKKDLGGKFSTWANEELQLGDVIDVMNPQGAFTSKIHVTSLN
HHHCCEECCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEECC
DAQNLVDSELGQVENPNFVAIAAGSGITPIMSIAQAVLKSLPKATFQLVYSNKGGADVMF
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
ADKIGDLKDKYPARFAVHHVLTREQRVNPLFSGRIDDEKMELLLDQVLRPDLVDEWFLCG
ECCCCCHHHHCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCC
PFELVQMCRDSLKERDIDEKRIRFELFSTGDPKSAPGGNAGRPVIADPKGKNISIQFQLD
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEC
GLSGTIESPVSAKETVLNAALRARPDVPFACAGGVCGTCRAKVVEGDYEMDENYALEPDE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCHH
VAAGYVLTCQTRPTGDCITVDYDA
HCCCEEEEECCCCCCCEEEEECCC
>Mature Secondary Structure 
TSVIKKKAKFNTLSVSGVKKLTDDSVEVSFDVPEELQDDYDYIPGQYVALRATVDGEEL
CHHHHHHHCCCEEEECCHHHCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEEECCHHHH
RRSYSICDIPNKGTIRVGIKKDLGGKFSTWANEELQLGDVIDVMNPQGAFTSKIHVTSLN
HHHCCEECCCCCCEEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEEEEEECC
DAQNLVDSELGQVENPNFVAIAAGSGITPIMSIAQAVLKSLPKATFQLVYSNKGGADVMF
HHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEE
ADKIGDLKDKYPARFAVHHVLTREQRVNPLFSGRIDDEKMELLLDQVLRPDLVDEWFLCG
ECCCCCHHHHCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCC
PFELVQMCRDSLKERDIDEKRIRFELFSTGDPKSAPGGNAGRPVIADPKGKNISIQFQLD
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCEEEEEEEEC
GLSGTIESPVSAKETVLNAALRARPDVPFACAGGVCGTCRAKVVEGDYEMDENYALEPDE
CCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCHH
VAAGYVLTCQTRPTGDCITVDYDA
HCCCEEEEECCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]