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The map label for this gene is menC [H]

Identifier: 145294618

GI number: 145294618

Start: 626462

End: 627478

Strand: Direct

Name: menC [H]

Synonym: cgR_0569

Alternate gene names: 145294618

Gene position: 626462-627478 (Clockwise)

Preceding gene: 145294617

Following gene: 145294619

Centisome position: 18.9

GC content: 58.41

Gene sequence:

>1017_bases
ATGAGCACCCCAACTGTTGATGAGATTCTAGAGCGCGCCCACGTGGTGTCGCTGCCGATGCGTGTGAAGTTTCGTGGCGT
CACCACCAGGGAGGCTTTGCTGATTGAAGGCCCTGCTGGTTGGGGAGAGTTCGCGCCCTTCCTTGAGTATGACCCGCAAG
AATCGGCCAGTTGGCTAAAGTCCGGCATTGAAGCAGCGTGGGAGGGTTTTCCGGCGCCGTTGCGTGATCGCGTGGAAGTC
AATGCCACCATCCCAGCTGTTCCGGTCGATCAAGTGGCAGAAGTTTTGGACCGTTTCCCAGGCTGTCGCACCATCAAAGT
AAAGGTCGCGGAACCAGGCCAGACCTTGACTGATGACATCGCGCGAGTTGCCGCTGTCCGTGAGGCACGCCCCGGCGCGA
TCATCCGTGTTGATGCCAATTGTGGGTGGAGTGTGGAGCAGGCGGTGGAGGCGGCTCAGGCGTTGGCGCCGTTGGATTAT
TTAGAGCAGCCGTGTGCCACCGTGGAGGAACTGGCGGAAGTGCGCATGACGGTGCAGCGGCGCGGACTTTTTGTGCGCGT
CGCAGCGGATGAATCGATCAGAAAATCTGATGATCCTTATCGGGTGGCGGATCTGCGTGCTGCGGATGTGGCTGTGGTGA
AGGTTGCTCCTTTGGGTGGTGTGAAAAGGGTACTTGAGGTGGCGCAACATTTGCGGGCGCGCACGATGGACATCACTGTA
GCAAGTGCGTTGGACACGGTTGTGGGGATGAATGCTGGGTTGGCTGCGGTGGCGGCGTTGCCGAAGTTGGATGATGACGA
TCTCATTGATGTGCCACCAGCGGCGGCGGGTCTTGCGACTTCGCAGTTGTTCCTGGAGGATGTCGCGACCCCGCACGCAA
TCACTGATGGGTTCATGGAAACGCGTGTAATTGCCCCGGAAATGGATCGTTTGGAAACGCTTGCTGCCAGCAAAGATAGG
CGTGATTGGTGGTTTGCGCGCGTGCGTGAATCGTATCCGTACCTGGAGACAATCTAG

Upstream 100 bases:

>100_bases
TGCGCACCTACGGCGCCGAATTCCCGCTGGTCCTGCTTAAAGATGGACAGGCACTGCTTATCGACGACCACGGCGTCCAC
CTAATTTAGGATGGTTCCCC

Downstream 100 bases:

>100_bases
ACTGTTGTGCATGTCCAGCACGCCAGCTCAAGATCTTGCCCGCGCCGTTATTGATTCCCTCGCACCACACGTCACTGACG
TGGTGTTATGCCCAGGATCC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSTPTVDEILERAHVVSLPMRVKFRGVTTREALLIEGPAGWGEFAPFLEYDPQESASWLKSGIEAAWEGFPAPLRDRVEV
NATIPAVPVDQVAEVLDRFPGCRTIKVKVAEPGQTLTDDIARVAAVREARPGAIIRVDANCGWSVEQAVEAAQALAPLDY
LEQPCATVEELAEVRMTVQRRGLFVRVAADESIRKSDDPYRVADLRAADVAVVKVAPLGGVKRVLEVAQHLRARTMDITV
ASALDTVVGMNAGLAAVAALPKLDDDDLIDVPPAAAGLATSQLFLEDVATPHAITDGFMETRVIAPEMDRLETLAASKDR
RDWWFARVRESYPYLETI

Sequences:

>Translated_338_residues
MSTPTVDEILERAHVVSLPMRVKFRGVTTREALLIEGPAGWGEFAPFLEYDPQESASWLKSGIEAAWEGFPAPLRDRVEV
NATIPAVPVDQVAEVLDRFPGCRTIKVKVAEPGQTLTDDIARVAAVREARPGAIIRVDANCGWSVEQAVEAAQALAPLDY
LEQPCATVEELAEVRMTVQRRGLFVRVAADESIRKSDDPYRVADLRAADVAVVKVAPLGGVKRVLEVAQHLRARTMDITV
ASALDTVVGMNAGLAAVAALPKLDDDDLIDVPPAAAGLATSQLFLEDVATPHAITDGFMETRVIAPEMDRLETLAASKDR
RDWWFARVRESYPYLETI
>Mature_337_residues
STPTVDEILERAHVVSLPMRVKFRGVTTREALLIEGPAGWGEFAPFLEYDPQESASWLKSGIEAAWEGFPAPLRDRVEVN
ATIPAVPVDQVAEVLDRFPGCRTIKVKVAEPGQTLTDDIARVAAVREARPGAIIRVDANCGWSVEQAVEAAQALAPLDYL
EQPCATVEELAEVRMTVQRRGLFVRVAADESIRKSDDPYRVADLRAADVAVVKVAPLGGVKRVLEVAQHLRARTMDITVA
SALDTVVGMNAGLAAVAALPKLDDDDLIDVPPAAAGLATSQLFLEDVATPHAITDGFMETRVIAPEMDRLETLAASKDRR
DWWFARVRESYPYLETI

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36845; Mature: 36714

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTVDEILERAHVVSLPMRVKFRGVTTREALLIEGPAGWGEFAPFLEYDPQESASWLK
CCCCCHHHHHHHHHHEECCEEEEEECCCEECEEEEECCCCCCCCCCCCCCCCHHHHHHHH
SGIEAAWEGFPAPLRDRVEVNATIPAVPVDQVAEVLDRFPGCRTIKVKVAEPGQTLTDDI
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ARVAAVREARPGAIIRVDANCGWSVEQAVEAAQALAPLDYLEQPCATVEELAEVRMTVQR
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RGLFVRVAADESIRKSDDPYRVADLRAADVAVVKVAPLGGVKRVLEVAQHLRARTMDITV
CCEEEEEECCCHHHCCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ASALDTVVGMNAGLAAVAALPKLDDDDLIDVPPAAAGLATSQLFLEDVATPHAITDGFME
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
TRVIAPEMDRLETLAASKDRRDWWFARVRESYPYLETI
HEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCC
>Mature Secondary Structure 
STPTVDEILERAHVVSLPMRVKFRGVTTREALLIEGPAGWGEFAPFLEYDPQESASWLK
CCCCHHHHHHHHHHEECCEEEEEECCCEECEEEEECCCCCCCCCCCCCCCCHHHHHHHH
SGIEAAWEGFPAPLRDRVEVNATIPAVPVDQVAEVLDRFPGCRTIKVKVAEPGQTLTDDI
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ARVAAVREARPGAIIRVDANCGWSVEQAVEAAQALAPLDYLEQPCATVEELAEVRMTVQR
HHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RGLFVRVAADESIRKSDDPYRVADLRAADVAVVKVAPLGGVKRVLEVAQHLRARTMDITV
CCEEEEEECCCHHHCCCCCEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ASALDTVVGMNAGLAAVAALPKLDDDDLIDVPPAAAGLATSQLFLEDVATPHAITDGFME
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
TRVIAPEMDRLETLAASKDRRDWWFARVRESYPYLETI
HEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]