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The map label for this gene is clpX [H]

Identifier: 138896218

GI number: 138896218

Start: 2688211

End: 2689476

Strand: Reverse

Name: clpX [H]

Synonym: GTNG_2581

Alternate gene names: 138896218

Gene position: 2689476-2688211 (Counterclockwise)

Preceding gene: 138896219

Following gene: 138896217

Centisome position: 75.75

GC content: 48.5

Gene sequence:

>1266_bases
ATGTTTAAATTTAACGATGAAAAAGGGCAGTTGAAATGTTCGTTTTGTGGCAAAACACAAGACCAAGTGCGCAAGTTGGT
CGCTGGGCCGGGTGTGTACATTTGCGATGAGTGCATCGAGCTATGCACGGAGATCGTCGAAGAAGAGCTTGGCAATGAGG
AAGAGTTCGAGTTTAAAGATGTGCCAAAGCCGGTGGAAATCCGTGAAATTCTAGATGAATACGTCATCGGCCAGGACGAG
GCGAAAAAATCGCTTGCCGTTGCCGTTTATAATCATTATAAACGGATTAACTCCGGCAGCAAAATTGACGATGTAGAGCT
GTCGAAAAGCAACATTTTGATGATCGGGCCGACTGGAAGCGGGAAAACGCTCTTGGCGCAAACATTGGCACGTATTTTAA
ACGTACCGTTTGCTATTGCTGATGCGACATCGCTCACGGAAGCGGGCTATGTTGGCGAGGACGTCGAAAACATTTTGCTG
AAGCTTATTCAAGCGGCTGACTACGATGTCGAACGGGCAGAAAAAGGCATTATTTACATCGACGAAATCGATAAAATTGC
CCGCAAGTCGGAAAACCCTTCCATTACCCGCGATGTTTCGGGTGAAGGGGTGCAGCAGGCCCTGTTGAAAATTTTGGAAG
GCACGATCGCCAGCGTTCCGCCGCAGGGTGGCCGCAAACATCCGCATCAAGAGTTTATTCAAATTGATACGACGAACATT
TTGTTTATTTGCGGCGGGGCGTTTGACGGAATTGAGCCGATCATCAAGCGCCGCCTCGGCAAAAAAGTGATCGGGTTTGG
TGCTGAAATGAACCAAGCTGACGTTGATGAGAAAAACTTGCTGTCGAAAGTGTTGCCGGAAGACTTGCTCAAGTTTGGTC
TCATTCCGGAGTTCATCGGCCGCCTGCCGGTCATTACTACGCTTGAACCGCTCGATGAACAAGCGTTGATTGATATTTTG
ACGAAGCCGAAAAACGCCATTGTGAAGCAATACAAAAAAATGCTCGAGCTTGACGGCGTTGAGCTTGAGTTTGAAGAAGC
CGCACTCCGTGAAATCGCGAAAAAAGCAATTGAACGGAAAACGGGAGCGCGCGGTCTCCGTTCGATCATCGAAGGCATTA
TGCTCGATGTCATGTTTGAGCTTCCGTCGCGCGAAGATGTGCAAAAATGTATCATTACTGTCGATACCGTGTGCGGCAAA
AAACCACCGAAACTCATTCGCCATGACGGCACGGTGGTCGAGCACGAACGGAAAACGTCCGCTTAA

Upstream 100 bases:

>100_bases
CACTTATGGTAAAATAGCGAATACATACGTTTTTGCAACGAAGGATGGCGACACACGATACATAACGCAGGCGTGATTCC
GTTAACAAGGGGTGAATAAC

Downstream 100 bases:

>100_bases
TGAGGGAAACCGCCTTTTACGGCGGTTTCTTTTTTGTTGCATGCCCTAGGCGCCAGTCGGCGCTTTTTTTGTTTATTCCC
GCCAATTCGCGGAGATACTA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKDVPKPVEIREILDEYVIGQDE
AKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIGRLPVITTLEPLDEQALIDIL
TKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGK
KPPKLIRHDGTVVEHERKTSA

Sequences:

>Translated_421_residues
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKDVPKPVEIREILDEYVIGQDE
AKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIGRLPVITTLEPLDEQALIDIL
TKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGK
KPPKLIRHDGTVVEHERKTSA
>Mature_421_residues
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKDVPKPVEIREILDEYVIGQDE
AKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIGRLPVITTLEPLDEQALIDIL
TKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERKTGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGK
KPPKLIRHDGTVVEHERKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=334, Percent_Identity=50.8982035928144, Blast_Score=319, Evalue=3e-87,
Organism=Escherichia coli, GI1786642, Length=400, Percent_Identity=64, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=46.6019417475728, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=330, Percent_Identity=45.1515151515152, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI71982905, Length=330, Percent_Identity=45.1515151515152, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=431, Percent_Identity=37.5870069605568, Blast_Score=254, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=38.8461538461538, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=419, Percent_Identity=39.3794749403341, Blast_Score=269, Evalue=7e-73,
Organism=Drosophila melanogaster, GI24648291, Length=333, Percent_Identity=48.948948948949, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24648289, Length=333, Percent_Identity=48.948948948949, Blast_Score=307, Evalue=7e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46761; Mature: 46761

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPVEIREILDEYVIGQDEAKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGS
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVERAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIG
EEEECCCCCCHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHC
RLPVITTLEPLDEQALIDILTKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERK
CCCCEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGKKPPKLIRHDGTVVEHERKTS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCC
A
C
>Mature Secondary Structure
MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGNEEEFEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPVEIREILDEYVIGQDEAKKSLAVAVYNHYKRINSGSKIDDVELSKSNILMIGPTGS
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVERAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEPIIKRRLGKKVIGFGAEMNQADVDEKNLLSKVLPEDLLKFGLIPEFIG
EEEECCCCCCHHHHHHHHHCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHC
RLPVITTLEPLDEQALIDILTKPKNAIVKQYKKMLELDGVELEFEEAALREIAKKAIERK
CCCCEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFELPSREDVQKCIITVDTVCGKKPPKLIRHDGTVVEHERKTS
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA