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The map label for this gene is tig [H]

Identifier: 138896219

GI number: 138896219

Start: 2689706

End: 2691028

Strand: Reverse

Name: tig [H]

Synonym: GTNG_2582

Alternate gene names: 138896219

Gene position: 2691028-2689706 (Counterclockwise)

Preceding gene: 138896220

Following gene: 138896218

Centisome position: 75.8

GC content: 47.77

Gene sequence:

>1323_bases
ATGATCCTAGCAATGATTTTAGGTGGAGGGAACAGTATGTCAGTCAAATGGGAAAAGCTTGAAGGCAACGAAGGCGTATT
GACCGTTGAGGTCGACGCTGAACAAGTGAACAAAGGCTTGGACGCCGCATTCAAAAAAGTGGTGAAAAACGTCTCGCTTC
CGGGCTTCCGTAAAGGGAAAGTACCGCGCGTCTTGTTTGAAAAACGCTTTGGCGTTGAAGCGCTCTATCAAGATGCGCTC
GACATTTTGCTGCCGGAAGCGTATGCGAAAGCGGTCGAAGAAGCAGGCATTGAGCCGGTATCGATGCCGGAAATCGACAT
TGAGCAAATGGAAAAAGGCAAAAGCTTAATTTTTAAAGCGAAAGTCACTGTTAAACCGGAAGTAAAACTCGGTCAATACA
AAGGACTTGAGGTTGAAAAAATCGATACGACGGTAACGGATGAAGATGTCGAAAATAAGCTGAAGCGCCTGCAAGAAAAC
TATGCTGAACTGGTCGTCAAAGAAGAAGGGACAGTGGAAAACGGTGATACGGCCGTCATCGACTTTGAAGGATTTGTCGA
CGGCGAACCGTTTGAAGGTGGCAAAGCAGAAAACTATTCGCTCGAAATCGGCTCCGGAACGTTCATTCCTGGGTTTGAAG
ATCAGCTTGTCGGCATGAAAGCGGGAGAAGAAAAAGAAATTCAAGTCACCTTCCCGGAAGAGTATCATGCTGAACAACTG
GCGGGCAAACCGGCGACGTTCAAAGTGAAAGTACACGAAGTGAAAGCGAAACAACTGCCGGCGCTTGACGATGAATTCGC
AAAAGATGTCGATGAAGAAGTCGAAACGCTTGACGAACTGAAGTCGAAAATCCGCACTCGTTTAGAAGAAGCGAAGAAGA
ACGAGGCAGAAGCGGCCGTTCGCAACGCAGTTGTTGAGAAAGCAGCGGCCAACGCGGAAATCGATATTCCGGCTGTCATG
GTGCAAAATGAGACTGACCGGATGCTTCGCGAATTTGACCAACGTCTGCAAATGCAAGGAATGAACTTGCAGTTGTACTA
TCAATTCTCCGGCCAGGACGAAGCAGCGTTGCGTGAACAAATGAAAGAAGATGCTGAAAAGCGGGTGCGCGCAGCACTGA
CGCTTGAAGCGATCGCCAAAGCAGAAAATATCGACGTGACTGACGAAGAAGTGAATGAAGAGCTCGAAAAAATGGCCGCA
TCCTACAACTTGAGCGTTGACAAGTTAAAAGAGCTGATCGGCAACCTCGACGGCGTCAAAGAAGATTTAAAATGGCGAAA
AACGGTCGATTTTCTTGTAGAGCACAGCACGGTTGCGGCATAA

Upstream 100 bases:

>100_bases
TGTATGTTATAATATAATGGCTGTGCTATGTATCTGTTTTCGCATACTTGGCTACATAATATGGACATAATAAAAGGATA
ATGGACAAGCAGATTGCGCC

Downstream 100 bases:

>100_bases
TAATGAAGTAGGGAAGGAACAAGGCGCGAAACGTTCGTGCCTTGTTCTTTATCTCATCAATGGCGATTGGAGGATGAGTT
TTCAAACTTTTCTAACACAT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MILAMILGGGNSMSVKWEKLEGNEGVLTVEVDAEQVNKGLDAAFKKVVKNVSLPGFRKGKVPRVLFEKRFGVEALYQDAL
DILLPEAYAKAVEEAGIEPVSMPEIDIEQMEKGKSLIFKAKVTVKPEVKLGQYKGLEVEKIDTTVTDEDVENKLKRLQEN
YAELVVKEEGTVENGDTAVIDFEGFVDGEPFEGGKAENYSLEIGSGTFIPGFEDQLVGMKAGEEKEIQVTFPEEYHAEQL
AGKPATFKVKVHEVKAKQLPALDDEFAKDVDEEVETLDELKSKIRTRLEEAKKNEAEAAVRNAVVEKAAANAEIDIPAVM
VQNETDRMLREFDQRLQMQGMNLQLYYQFSGQDEAALREQMKEDAEKRVRAALTLEAIAKAENIDVTDEEVNEELEKMAA
SYNLSVDKLKELIGNLDGVKEDLKWRKTVDFLVEHSTVAA

Sequences:

>Translated_440_residues
MILAMILGGGNSMSVKWEKLEGNEGVLTVEVDAEQVNKGLDAAFKKVVKNVSLPGFRKGKVPRVLFEKRFGVEALYQDAL
DILLPEAYAKAVEEAGIEPVSMPEIDIEQMEKGKSLIFKAKVTVKPEVKLGQYKGLEVEKIDTTVTDEDVENKLKRLQEN
YAELVVKEEGTVENGDTAVIDFEGFVDGEPFEGGKAENYSLEIGSGTFIPGFEDQLVGMKAGEEKEIQVTFPEEYHAEQL
AGKPATFKVKVHEVKAKQLPALDDEFAKDVDEEVETLDELKSKIRTRLEEAKKNEAEAAVRNAVVEKAAANAEIDIPAVM
VQNETDRMLREFDQRLQMQGMNLQLYYQFSGQDEAALREQMKEDAEKRVRAALTLEAIAKAENIDVTDEEVNEELEKMAA
SYNLSVDKLKELIGNLDGVKEDLKWRKTVDFLVEHSTVAA
>Mature_440_residues
MILAMILGGGNSMSVKWEKLEGNEGVLTVEVDAEQVNKGLDAAFKKVVKNVSLPGFRKGKVPRVLFEKRFGVEALYQDAL
DILLPEAYAKAVEEAGIEPVSMPEIDIEQMEKGKSLIFKAKVTVKPEVKLGQYKGLEVEKIDTTVTDEDVENKLKRLQEN
YAELVVKEEGTVENGDTAVIDFEGFVDGEPFEGGKAENYSLEIGSGTFIPGFEDQLVGMKAGEEKEIQVTFPEEYHAEQL
AGKPATFKVKVHEVKAKQLPALDDEFAKDVDEEVETLDELKSKIRTRLEEAKKNEAEAAVRNAVVEKAAANAEIDIPAVM
VQNETDRMLREFDQRLQMQGMNLQLYYQFSGQDEAALREQMKEDAEKRVRAALTLEAIAKAENIDVTDEEVNEELEKMAA
SYNLSVDKLKELIGNLDGVKEDLKWRKTVDFLVEHSTVAA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=416, Percent_Identity=34.1346153846154, Blast_Score=207, Evalue=9e-55,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 49082; Mature: 49082

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAMILGGGNSMSVKWEKLEGNEGVLTVEVDAEQVNKGLDAAFKKVVKNVSLPGFRKGK
CEEEEEECCCCCCEEEEEEECCCCCEEEEEECHHHHHCCHHHHHHHHHHHCCCCCCCCCC
VPRVLFEKRFGVEALYQDALDILLPEAYAKAVEEAGIEPVSMPEIDIEQMEKGKSLIFKA
CCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEEEEEE
KVTVKPEVKLGQYKGLEVEKIDTTVTDEDVENKLKRLQENYAELVVKEEGTVENGDTAVI
EEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEE
DFEGFVDGEPFEGGKAENYSLEIGSGTFIPGFEDQLVGMKAGEEKEIQVTFPEEYHAEQL
EECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCEEEEECCHHHHHHHH
AGKPATFKVKVHEVKAKQLPALDDEFAKDVDEEVETLDELKSKIRTRLEEAKKNEAEAAV
CCCCCEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNAVVEKAAANAEIDIPAVMVQNETDRMLREFDQRLQMQGMNLQLYYQFSGQDEAALREQ
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
MKEDAEKRVRAALTLEAIAKAENIDVTDEEVNEELEKMAASYNLSVDKLKELIGNLDGVK
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
EDLKWRKTVDFLVEHSTVAA
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILAMILGGGNSMSVKWEKLEGNEGVLTVEVDAEQVNKGLDAAFKKVVKNVSLPGFRKGK
CEEEEEECCCCCCEEEEEEECCCCCEEEEEECHHHHHCCHHHHHHHHHHHCCCCCCCCCC
VPRVLFEKRFGVEALYQDALDILLPEAYAKAVEEAGIEPVSMPEIDIEQMEKGKSLIFKA
CCHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEEEEEE
KVTVKPEVKLGQYKGLEVEKIDTTVTDEDVENKLKRLQENYAELVVKEEGTVENGDTAVI
EEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEE
DFEGFVDGEPFEGGKAENYSLEIGSGTFIPGFEDQLVGMKAGEEKEIQVTFPEEYHAEQL
EECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCEEEEECCHHHHHHHH
AGKPATFKVKVHEVKAKQLPALDDEFAKDVDEEVETLDELKSKIRTRLEEAKKNEAEAAV
CCCCCEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNAVVEKAAANAEIDIPAVMVQNETDRMLREFDQRLQMQGMNLQLYYQFSGQDEAALREQ
HHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
MKEDAEKRVRAALTLEAIAKAENIDVTDEEVNEELEKMAASYNLSVDKLKELIGNLDGVK
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
EDLKWRKTVDFLVEHSTVAA
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA