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The map label for this gene is comEB [H]

Identifier: 138896089

GI number: 138896089

Start: 2561356

End: 2561823

Strand: Reverse

Name: comEB [H]

Synonym: GTNG_2452

Alternate gene names: 138896089

Gene position: 2561823-2561356 (Counterclockwise)

Preceding gene: 138896090

Following gene: 138896088

Centisome position: 72.16

GC content: 53.63

Gene sequence:

>468_bases
ATGGAACGAATGACATGGGACCAATATTTTATGGCGCAAAGCCATTTGTTGGCGCTGCGCAGCACGTGTACAAGGCTTGC
GGTCGGGGCGACGATCGTGCGCGACAAACGCATTATCGCCGGTGGATATAACGGCTCGATCGCCGGTGGCGCCCATTGCA
TTGATGAAGGGTGCTACGTCATTGATGGCCATTGTGTGCGAACGATCCACGCGGAAATGAACGCGATTTTGCAATGCGCC
AAGTTTGGCGTCCCGACGGAAGGCGCCGAGATGTATGTCACCCATTTTCCTTGCTTGCATTGCTGTAAGGCGATTATTCA
AAGCGGCATTCGCGCTGTGTATTATGCGCAAGATTACAAAAACCATCCGTATGCCCTTGAACTGTTTGCCCAAGCCGGCG
TCCGCCTCGTGCAAGTGCCGTTGAAGATGGATGTGTTTGCCCAACTTTCCGGCGGAGGGGAAACATGA

Upstream 100 bases:

>100_bases
AGTCAGAGGGAGGAACGATGATAACCAACTTTTTTCAGCATTGACGGCGCTTTAGGTGACCGATAGACTAAAATTATCGA
GACAAGCGGAGGGACATGAT

Downstream 100 bases:

>100_bases
AAGGGCAAGCCGTTTACATCGCCGTGGCGGCGCTCTTGGCCGCTGCGGCTGCCTCTTTGTCCAAACCTGCATTTTTCCTC
CTTGTCGGCTATCTCCTTCT

Product: late competence protein ComEB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MERMTWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGAHCIDEGCYVIDGHCVRTIHAEMNAILQCA
KFGVPTEGAEMYVTHFPCLHCCKAIIQSGIRAVYYAQDYKNHPYALELFAQAGVRLVQVPLKMDVFAQLSGGGET

Sequences:

>Translated_155_residues
MERMTWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGAHCIDEGCYVIDGHCVRTIHAEMNAILQCA
KFGVPTEGAEMYVTHFPCLHCCKAIIQSGIRAVYYAQDYKNHPYALELFAQAGVRLVQVPLKMDVFAQLSGGGET
>Mature_155_residues
MERMTWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGAHCIDEGCYVIDGHCVRTIHAEMNAILQCA
KFGVPTEGAEMYVTHFPCLHCCKAIIQSGIRAVYYAQDYKNHPYALELFAQAGVRLVQVPLKMDVFAQLSGGGET

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742821, Length=143, Percent_Identity=37.7622377622378, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI61742819, Length=143, Percent_Identity=37.7622377622378, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321938, Length=142, Percent_Identity=37.3239436619718, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667298, Length=137, Percent_Identity=37.956204379562, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667302, Length=137, Percent_Identity=37.956204379562, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17018; Mature: 17018

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERMTWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGAHCIDEGCYV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCCCCCCCHHHCCCCEE
IDGHCVRTIHAEMNAILQCAKFGVPTEGAEMYVTHFPCLHCCKAIIQSGIRAVYYAQDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCC
NHPYALELFAQAGVRLVQVPLKMDVFAQLSGGGET
CCCHHHHHHHHCCCEEEEECCCCEEEEEECCCCCC
>Mature Secondary Structure
MERMTWDQYFMAQSHLLALRSTCTRLAVGATIVRDKRIIAGGYNGSIAGGAHCIDEGCYV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCCCCCCCHHHCCCCEE
IDGHCVRTIHAEMNAILQCAKFGVPTEGAEMYVTHFPCLHCCKAIIQSGIRAVYYAQDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEECCCC
NHPYALELFAQAGVRLVQVPLKMDVFAQLSGGGET
CCCHHHHHHHHCCCEEEEECCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]