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The map label for this gene is namA [H]

Identifier: 138895903

GI number: 138895903

Start: 2376177

End: 2377199

Strand: Direct

Name: namA [H]

Synonym: GTNG_2262

Alternate gene names: 138895903

Gene position: 2376177-2377199 (Clockwise)

Preceding gene: 138895902

Following gene: 138895905

Centisome position: 66.93

GC content: 56.11

Gene sequence:

>1023_bases
ATGAACACGGTATTGTTTTCGCCATATACAACTCGCGGGCTAACGTTGAAAAACCGGATCGTTATGTCGCCGATGTGCAT
GTACTCGTGCGACACGAAAGACGGCACGGTACGCACATGGCATAAAATCCACTACCCGGCACGCGCGATCGGCCAAGTCG
GCCTCATCATTGTCGAGGCGACCGGCGTTACGCCACAAGGCCGCATTTCTGAACACGACCTAGGCATCTGGGACGATGAT
CATATCCATGGGCTTCACGAACTCGTTGGACTCGTGAAAGAGCATGGAGCTGCTATCGGCATCCAACTCGCTCACGCCGG
AAGAAAGTCGGAAGTGCCGGGAGAAATCATCGCCCCGTCCGCCATTCCGTTCAATGAATCATCGCCAACACCGAAAGAAA
TGACGAAAGCCGACATCGAAAAGACGGTGCAGGCGTTCCAAGACGGCGCGCGGCGGGCGAAAAAAGCCGGGTTTGACGTA
ATTGAAATCCACGCTGCCCACGGCTACCTTATTAACGAATTTCTATCGCCGCTGTCCAACCGGCGTCAAGACGAATACGG
CGGCTCGCCGGAAAACCGGTACCACTTTTTGGGCGAGGTGATCGACGCTGTCCGTGAAGTGTGGGACGGACCGCTGTTCG
TCCGCATCTCGGCATCTGACTACCATCCGGACGGACTAACGGTGAAAGACTATGTCCCGTACGTCAAGCGGATGAAAGAA
CAAGGGGTCGACCTTGTCGACGTCAGCTCCGGCGCTGTTGTACCGGCGCGCATTGACGTCTATCCTGGCTACCAAGTGCC
GTTTGCTGAATTCATCCGACGCGAAGCAGGCATTCCGACCGGCGCCGTCGGCCTGATCACTTCCGGCTGGCAGGCCGAAG
AAGTGTTGCATAACGGCCGCGCCGACCTTGTCTTTTTAGGACGTGAACTGCTGCGCAACCCGTATTGGCCGTATGCTGCC
GCTAAAGAACTTGGCGTAAAAATTGAAGCACCGGTGCAATACGAGCGCGGCTGGCGATTTTAA

Upstream 100 bases:

>100_bases
GTTGGGCAAATCATCGGACCGTTTCATTTTGTTTTTTGACCGGCAGCATGCTATCATTCAGTCATGAACCGTTCATTCGC
ATAGAAAGGAGTGGATTGTC

Downstream 100 bases:

>100_bases
CGCGGAATCGAAAATGAAGCAAAATCGGCGGCGAGCTCGGTGTTCGGAAACACGCGGCGCGCCTCCTCCAATAACTTGAG
CGCCGCTTCACCTTGGTAGC

Product: NADPH dehydrogenase NamA

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEATGVTPQGRISEHDLGIWDDD
HIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPSAIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDV
IEIHAAHGYLINEFLSPLSNRRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKE
QGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGRADLVFLGRELLRNPYWPYAA
AKELGVKIEAPVQYERGWRF

Sequences:

>Translated_340_residues
MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEATGVTPQGRISEHDLGIWDDD
HIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPSAIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDV
IEIHAAHGYLINEFLSPLSNRRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKE
QGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGRADLVFLGRELLRNPYWPYAA
AKELGVKIEAPVQYERGWRF
>Mature_340_residues
MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEATGVTPQGRISEHDLGIWDDD
HIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPSAIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDV
IEIHAAHGYLINEFLSPLSNRRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKE
QGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGRADLVFLGRELLRNPYWPYAA
AKELGVKIEAPVQYERGWRF

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=317, Percent_Identity=29.9684542586751, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787939, Length=336, Percent_Identity=29.4642857142857, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=224, Percent_Identity=31.6964285714286, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=221, Percent_Identity=32.579185520362, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=218, Percent_Identity=30.2752293577982, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=249, Percent_Identity=28.9156626506024, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=352, Percent_Identity=28.4090909090909, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=305, Percent_Identity=25.5737704918033, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=266, Percent_Identity=28.1954887218045, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=239, Percent_Identity=31.3807531380753, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321973, Length=236, Percent_Identity=30.9322033898305, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 37782; Mature: 37782

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEA
CCCEEECCCCCCCEEECCCEEECCHHEEECCCCCCCEEEHHHHCCCHHHHCCEEEEEEEE
TGVTPQGRISEHDLGIWDDDHIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEECCC
AIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDVIEIHAAHGYLINEFLSPLSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
RRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKE
CCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGR
CCCCEEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHEECCCCHHHHHHCCC
ADLVFLGRELLRNPYWPYAAAKELGVKIEAPVQYERGWRF
CCEEHCCHHHHCCCCCCCHHHHHHCCEEECCCCCCCCCCC
>Mature Secondary Structure
MNTVLFSPYTTRGLTLKNRIVMSPMCMYSCDTKDGTVRTWHKIHYPARAIGQVGLIIVEA
CCCEEECCCCCCCEEECCCEEECCHHEEECCCCCCCEEEHHHHCCCHHHHCCEEEEEEEE
TGVTPQGRISEHDLGIWDDDHIHGLHELVGLVKEHGAAIGIQLAHAGRKSEVPGEIIAPS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEECCC
AIPFNESSPTPKEMTKADIEKTVQAFQDGARRAKKAGFDVIEIHAAHGYLINEFLSPLSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
RRQDEYGGSPENRYHFLGEVIDAVREVWDGPLFVRISASDYHPDGLTVKDYVPYVKRMKE
CCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLVDVSSGAVVPARIDVYPGYQVPFAEFIRREAGIPTGAVGLITSGWQAEEVLHNGR
CCCCEEECCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCHHHEECCCCHHHHHHCCC
ADLVFLGRELLRNPYWPYAAAKELGVKIEAPVQYERGWRF
CCEEHCCHHHHCCCCCCCHHHHHHCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA