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The map label for this gene is gmuC [H]

Identifier: 138895404

GI number: 138895404

Start: 1848980

End: 1850299

Strand: Reverse

Name: gmuC [H]

Synonym: GTNG_1748

Alternate gene names: 138895404

Gene position: 1850299-1848980 (Counterclockwise)

Preceding gene: 138895405

Following gene: 138895403

Centisome position: 52.12

GC content: 45.45

Gene sequence:

>1320_bases
ATGAACGGTGCTTTATTTGAGAAATTGAGCAAAGTGCTCGTTCCGGTCGCTGGAAAGTTGAATAACAGTCGTTATTTGCA
AGTGTTGCGTGATGCGTTTATGTTGGCGTTTCCGTTGACGATTTTCGGTTCGATCGCGGTCGTCATCGCCAACTTGCCGT
TTTTAGATAAGATCATGAGCGAAAGCAGCCTGAATATGTTAAAAGACATGCTTGGTGTTGCCCCGAATGCGACAATGGGG
GTGATGACGGTTTTCGTCGTGTTCGGCATAGGTTATTATTTGTCGAAAAGTTATGAAGTCGAGGGGATTTTTGGCGGCGC
GATTGCTTTAGCTTCATTTCTCTTATTGACGCCGTTTGTGGTCCAAATAGAAGGAAAGGAAGCGGTGCAAGGAGTCATTC
CGCTTGACCGTCTTGGAGCGAAAGGAATGTTCCTTGGGATGATTACCGCCTTTATCGCTGGGGAAATTTACAGAAAAGTT
GTGCAAAAAAACATTACAATTAAAATGCCGGCCGGGGTGCCACCGGCGGTTGCGAAGTCGTTTGCGGCATTAATTCCGGC
AGTGGTCACCCTGACCTTTTTCCTCGTCGTCAATATTATTGTAACACAAATGTTTCAAACAAACATGCATGATGTGATTT
ACAACGTTGTACAAGCCCCGCTTGTTGGTCTCGGGAGCGGCATTATTCCAACGTTGATTGCGATTTTTGTCGCACAAATT
TTATGGTTTTTTGGATTGCATGGGCAAATCATCATTAACTCGGTGATGGATCCGATTTGGAACACACTGTCGCTTGAAAA
CTTAAATGCGTACACACAAACCGGGGAAGTTCCGCATATCGTCAGCAAACAGTTTATTGAAATTTACACGGTCGGGATGG
GCGGAACGGGAATGACGCTTGCGGTCATTTTTGCGATATTGCTCTTTATGAAGAGCAAGCAAATGAAGCAGGTAGCTAAG
CTTGGGCTCGGACCCGGAATTTTCAATGTCAATGAACCGATCATTTTCGGTTTGCCAATAGTGATGAATCCGCTTGTTAT
CGTCCCGTGGATTTTGGCGCCAATGATCGTTACGTTGGTCACCTATTTGGCGATGTCCTCAGGGCTTGTGCCACCTCCAA
ATGGTGTGGCGGTGCCATGGACCGTGCCGATTTTTATTAACGGTATTATGGCGACAAACTCGCTAGCTGGTGGACTATTG
CAATTGGTCAATTTCTTGATTGTGCTCGTCATTTGGTTCCCGTTCTTAAAATTCATTGACCGGATGAACTTGCAAAAGGA
GAGAGAAGAGGAACAAGCCTCTGCAAAAAGTGCATCATAA

Upstream 100 bases:

>100_bases
GCGGAAGACCATGTTATGTCAACGTTGGCGATGAAAGAGATTGTGAAAGAGATGCTTGCTTTGTTAAAGGAGCGGAATAT
ATAAAAAGGAGGGCTGTCAA

Downstream 100 bases:

>100_bases
CTACGCAGCAAACGAGGTGAATCACGATGGAACAACAATCGAAGCAGTCAATCACGTACCGCTTCCCTGCCGGTTTTTGG
TGGGGAAGCGCGACGTCCGC

Product: PTS system cellobiose-specific transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Glucomannan utilization protein C; PTS system oligo-beta-mannoside-specific EIIC component [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MNGALFEKLSKVLVPVAGKLNNSRYLQVLRDAFMLAFPLTIFGSIAVVIANLPFLDKIMSESSLNMLKDMLGVAPNATMG
VMTVFVVFGIGYYLSKSYEVEGIFGGAIALASFLLLTPFVVQIEGKEAVQGVIPLDRLGAKGMFLGMITAFIAGEIYRKV
VQKNITIKMPAGVPPAVAKSFAALIPAVVTLTFFLVVNIIVTQMFQTNMHDVIYNVVQAPLVGLGSGIIPTLIAIFVAQI
LWFFGLHGQIIINSVMDPIWNTLSLENLNAYTQTGEVPHIVSKQFIEIYTVGMGGTGMTLAVIFAILLFMKSKQMKQVAK
LGLGPGIFNVNEPIIFGLPIVMNPLVIVPWILAPMIVTLVTYLAMSSGLVPPPNGVAVPWTVPIFINGIMATNSLAGGLL
QLVNFLIVLVIWFPFLKFIDRMNLQKEREEEQASAKSAS

Sequences:

>Translated_439_residues
MNGALFEKLSKVLVPVAGKLNNSRYLQVLRDAFMLAFPLTIFGSIAVVIANLPFLDKIMSESSLNMLKDMLGVAPNATMG
VMTVFVVFGIGYYLSKSYEVEGIFGGAIALASFLLLTPFVVQIEGKEAVQGVIPLDRLGAKGMFLGMITAFIAGEIYRKV
VQKNITIKMPAGVPPAVAKSFAALIPAVVTLTFFLVVNIIVTQMFQTNMHDVIYNVVQAPLVGLGSGIIPTLIAIFVAQI
LWFFGLHGQIIINSVMDPIWNTLSLENLNAYTQTGEVPHIVSKQFIEIYTVGMGGTGMTLAVIFAILLFMKSKQMKQVAK
LGLGPGIFNVNEPIIFGLPIVMNPLVIVPWILAPMIVTLVTYLAMSSGLVPPPNGVAVPWTVPIFINGIMATNSLAGGLL
QLVNFLIVLVIWFPFLKFIDRMNLQKEREEEQASAKSAS
>Mature_439_residues
MNGALFEKLSKVLVPVAGKLNNSRYLQVLRDAFMLAFPLTIFGSIAVVIANLPFLDKIMSESSLNMLKDMLGVAPNATMG
VMTVFVVFGIGYYLSKSYEVEGIFGGAIALASFLLLTPFVVQIEGKEAVQGVIPLDRLGAKGMFLGMITAFIAGEIYRKV
VQKNITIKMPAGVPPAVAKSFAALIPAVVTLTFFLVVNIIVTQMFQTNMHDVIYNVVQAPLVGLGSGIIPTLIAIFVAQI
LWFFGLHGQIIINSVMDPIWNTLSLENLNAYTQTGEVPHIVSKQFIEIYTVGMGGTGMTLAVIFAILLFMKSKQMKQVAK
LGLGPGIFNVNEPIIFGLPIVMNPLVIVPWILAPMIVTLVTYLAMSSGLVPPPNGVAVPWTVPIFINGIMATNSLAGGLL
QLVNFLIVLVIWFPFLKFIDRMNLQKEREEEQASAKSAS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=457, Percent_Identity=33.0415754923414, Blast_Score=221, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47598; Mature: 47598

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNGALFEKLSKVLVPVAGKLNNSRYLQVLRDAFMLAFPLTIFGSIAVVIANLPFLDKIMS
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ESSLNMLKDMLGVAPNATMGVMTVFVVFGIGYYLSKSYEVEGIFGGAIALASFLLLTPFV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCHH
VQIEGKEAVQGVIPLDRLGAKGMFLGMITAFIAGEIYRKVVQKNITIKMPAGVPPAVAKS
EEECCHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
FAALIPAVVTLTFFLVVNIIVTQMFQTNMHDVIYNVVQAPLVGLGSGIIPTLIAIFVAQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LWFFGLHGQIIINSVMDPIWNTLSLENLNAYTQTGEVPHIVSKQFIEIYTVGMGGTGMTL
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHEEECCCCCHHHH
AVIFAILLFMKSKQMKQVAKLGLGPGIFNVNEPIIFGLPIVMNPLVIVPWILAPMIVTLV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHH
TYLAMSSGLVPPPNGVAVPWTVPIFINGIMATNSLAGGLLQLVNFLIVLVIWFPFLKFID
HHHHHHCCCCCCCCCEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMNLQKEREEEQASAKSAS
HHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]