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The map label for this gene is gmuD [H]

Identifier: 138895403

GI number: 138895403

Start: 1847541

End: 1848953

Strand: Reverse

Name: gmuD [H]

Synonym: GTNG_1747

Alternate gene names: 138895403

Gene position: 1848953-1847541 (Counterclockwise)

Preceding gene: 138895404

Following gene: 138895402

Centisome position: 52.08

GC content: 47.35

Gene sequence:

>1413_bases
ATGGAACAACAATCGAAGCAGTCAATCACGTACCGCTTCCCTGCCGGTTTTTGGTGGGGAAGCGCGACGTCCGCAACGCA
AATGGAAGGGGCAGCCAACGAGGGGGGGAAAGGGAAAAATATTTGGGATCATTGGTATGAAAAGGAGCCACATCGCTTTT
TTAACGGCGTCGGCCCGTCAACTACATCAGATTTTTATCACCGCTACAAAGAGGATATTGCTTTGATGAAGGAGATCGGG
CATAATTCATTCCGGTTTTCGATTTCATGGTCACGCTTGATTCCAAAGGGAATCGGTGAGGTCAATCCGGAAGCCGTGCG
GTTTTACAATGCAGTCATCGATGAACTATTGGCGAGTGGGATCGAGCCATTTGTGAATTTGTATCATTTTGATATGCCGT
TAGCAATGCAAAATATCGGAGGTTGGGAAAACCGCGAAGTCGTGGATGCATACGCCCGCTACGCCAGCATTTGTTTTGAG
TTGTTCGGGGATCGGGTAAAAAAATGGTTTACCCACAATGAACCGATCGTTCCGGTGGAAGGAGGGTATTTATACGATTT
TCATTACCCAAACATCGTAGACTTCCGCCGTGCTGTACAAGTGGCTTACCATACGGTGATTGCCCATGCCAAAGCGGTTG
CCGCCTTCCGCAAGGCGGCCATCCCGGGAGGACAGATTGGCATCATTTTGAATTTGACGCCGTCTTACCCGCGCAGCCAG
CACCCAGCTGATGTAAAAGCGGCACATATTGCGGATTTGTTGTTTAACCGGAGTTTCTTAGATCCGGCGGTGAAAGGAGA
ATACCCGCAAGATTTGATTGAACTGTTGGATGAACATGGCTTTTTGCCTGTAACGGAAGCCGGTGATCGCGAGCTGATCA
AAGAAAACACGATCGATTTGCTCGGCATCAACTACTATCAACCGCGCCGCGTTAAGGCAAAAGAGCATCTCCCCAACCCG
GATGCCCCGTTTTTGCCGGAGCGATTTTTCGATTATTATGCTATGCCTGGACGGAAAATGAATCCGTATCGCGGTTGGGA
AATTTATGAAAAAGGCATTTATGATATTTTAATCAATATCAAAGAAAACTATGGAAACATTGAGTGCTTTATTTCTGAAA
ATGGCATGGGCGTCGAAGGGGAAGATCGGTTTCGTAATGAAAACGGCATGATTGATGACGACTACCGGATTGCTTTCATC
CGCGAACATTTAAAATGGGTGCATCGCGCGGTGGAAGAAGGGGTCAATGTGAAAGGCTATCACCTTTGGACGTTTATGGA
CAACTGGTCGTGGACCAATGCCTATAAAAATCGGTACGGGCTCGTCGCGGTTGATTTGGACAACGGCTTGAAGCGAACGA
TCAAAAAAAGTGGCTATTGGTTTAAAACAGTCGCGGAAAACAACGGATTTTGA

Upstream 100 bases:

>100_bases
TAAAATTCATTGACCGGATGAACTTGCAAAAGGAGAGAGAAGAGGAACAAGCCTCTGCAAAAAGTGCATCATAACTACGC
AGCAAACGAGGTGAATCACG

Downstream 100 bases:

>100_bases
ATGAAGGAAAAGGCGTCCCGGGGCAGCGGGGCGCCTTTTCTAGATTGAATGGATGAGGCAGCGTGAAAAGAGGAATGAGG
GGGAAAGTCACACTGGCTAT

Product: beta-glucosidase

Products: NA

Alternate protein names: Aryl-phospho-beta-D-glucosidase BglD; Glucomannan utilization protein D [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MEQQSKQSITYRFPAGFWWGSATSATQMEGAANEGGKGKNIWDHWYEKEPHRFFNGVGPSTTSDFYHRYKEDIALMKEIG
HNSFRFSISWSRLIPKGIGEVNPEAVRFYNAVIDELLASGIEPFVNLYHFDMPLAMQNIGGWENREVVDAYARYASICFE
LFGDRVKKWFTHNEPIVPVEGGYLYDFHYPNIVDFRRAVQVAYHTVIAHAKAVAAFRKAAIPGGQIGIILNLTPSYPRSQ
HPADVKAAHIADLLFNRSFLDPAVKGEYPQDLIELLDEHGFLPVTEAGDRELIKENTIDLLGINYYQPRRVKAKEHLPNP
DAPFLPERFFDYYAMPGRKMNPYRGWEIYEKGIYDILINIKENYGNIECFISENGMGVEGEDRFRNENGMIDDDYRIAFI
REHLKWVHRAVEEGVNVKGYHLWTFMDNWSWTNAYKNRYGLVAVDLDNGLKRTIKKSGYWFKTVAENNGF

Sequences:

>Translated_470_residues
MEQQSKQSITYRFPAGFWWGSATSATQMEGAANEGGKGKNIWDHWYEKEPHRFFNGVGPSTTSDFYHRYKEDIALMKEIG
HNSFRFSISWSRLIPKGIGEVNPEAVRFYNAVIDELLASGIEPFVNLYHFDMPLAMQNIGGWENREVVDAYARYASICFE
LFGDRVKKWFTHNEPIVPVEGGYLYDFHYPNIVDFRRAVQVAYHTVIAHAKAVAAFRKAAIPGGQIGIILNLTPSYPRSQ
HPADVKAAHIADLLFNRSFLDPAVKGEYPQDLIELLDEHGFLPVTEAGDRELIKENTIDLLGINYYQPRRVKAKEHLPNP
DAPFLPERFFDYYAMPGRKMNPYRGWEIYEKGIYDILINIKENYGNIECFISENGMGVEGEDRFRNENGMIDDDYRIAFI
REHLKWVHRAVEEGVNVKGYHLWTFMDNWSWTNAYKNRYGLVAVDLDNGLKRTIKKSGYWFKTVAENNGF
>Mature_470_residues
MEQQSKQSITYRFPAGFWWGSATSATQMEGAANEGGKGKNIWDHWYEKEPHRFFNGVGPSTTSDFYHRYKEDIALMKEIG
HNSFRFSISWSRLIPKGIGEVNPEAVRFYNAVIDELLASGIEPFVNLYHFDMPLAMQNIGGWENREVVDAYARYASICFE
LFGDRVKKWFTHNEPIVPVEGGYLYDFHYPNIVDFRRAVQVAYHTVIAHAKAVAAFRKAAIPGGQIGIILNLTPSYPRSQ
HPADVKAAHIADLLFNRSFLDPAVKGEYPQDLIELLDEHGFLPVTEAGDRELIKENTIDLLGINYYQPRRVKAKEHLPNP
DAPFLPERFFDYYAMPGRKMNPYRGWEIYEKGIYDILINIKENYGNIECFISENGMGVEGEDRFRNENGMIDDDYRIAFI
REHLKWVHRAVEEGVNVKGYHLWTFMDNWSWTNAYKNRYGLVAVDLDNGLKRTIKKSGYWFKTVAENNGF

Specific function: Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl-phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in viv

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=490, Percent_Identity=30.8163265306122, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI32481206, Length=488, Percent_Identity=32.5819672131148, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI13273313, Length=478, Percent_Identity=30.1255230125523, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI28376633, Length=469, Percent_Identity=30.4904051172708, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI24497614, Length=480, Percent_Identity=29.375, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI190360571, Length=97, Percent_Identity=38.1443298969072, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789070, Length=488, Percent_Identity=36.4754098360656, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI2367174, Length=486, Percent_Identity=35.1851851851852, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=32.0083682008368, Blast_Score=208, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17539390, Length=479, Percent_Identity=36.1169102296451, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI17552856, Length=472, Percent_Identity=34.3220338983051, Blast_Score=246, Evalue=1e-65,
Organism=Drosophila melanogaster, GI21356577, Length=490, Percent_Identity=31.6326530612245, Blast_Score=227, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54306; Mature: 54306

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQQSKQSITYRFPAGFWWGSATSATQMEGAANEGGKGKNIWDHWYEKEPHRFFNGVGPS
CCCCCCCCEEEECCCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCC
TTSDFYHRYKEDIALMKEIGHNSFRFSISWSRLIPKGIGEVNPEAVRFYNAVIDELLASG
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPFVNLYHFDMPLAMQNIGGWENREVVDAYARYASICFELFGDRVKKWFTHNEPIVPVE
HHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GGYLYDFHYPNIVDFRRAVQVAYHTVIAHAKAVAAFRKAAIPGGQIGIILNLTPSYPRSQ
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
HPADVKAAHIADLLFNRSFLDPAVKGEYPQDLIELLDEHGFLPVTEAGDRELIKENTIDL
CCCCHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHCCEEE
LGINYYQPRRVKAKEHLPNPDAPFLPERFFDYYAMPGRKMNPYRGWEIYEKGIYDILINI
EECCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCEEEEEEEE
KENYGNIECFISENGMGVEGEDRFRNENGMIDDDYRIAFIREHLKWVHRAVEEGVNVKGY
ECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
HLWTFMDNWSWTNAYKNRYGLVAVDLDNGLKRTIKKSGYWFKTVAENNGF
EEEEEECCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MEQQSKQSITYRFPAGFWWGSATSATQMEGAANEGGKGKNIWDHWYEKEPHRFFNGVGPS
CCCCCCCCEEEECCCCEECCCCCCCHHHCCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCC
TTSDFYHRYKEDIALMKEIGHNSFRFSISWSRLIPKGIGEVNPEAVRFYNAVIDELLASG
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
IEPFVNLYHFDMPLAMQNIGGWENREVVDAYARYASICFELFGDRVKKWFTHNEPIVPVE
HHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GGYLYDFHYPNIVDFRRAVQVAYHTVIAHAKAVAAFRKAAIPGGQIGIILNLTPSYPRSQ
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
HPADVKAAHIADLLFNRSFLDPAVKGEYPQDLIELLDEHGFLPVTEAGDRELIKENTIDL
CCCCHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHCCCEECCCCCCHHHHHHCCEEE
LGINYYQPRRVKAKEHLPNPDAPFLPERFFDYYAMPGRKMNPYRGWEIYEKGIYDILINI
EECCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCEEEEEEEE
KENYGNIECFISENGMGVEGEDRFRNENGMIDDDYRIAFIREHLKWVHRAVEEGVNVKGY
ECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
HLWTFMDNWSWTNAYKNRYGLVAVDLDNGLKRTIKKSGYWFKTVAENNGF
EEEEEECCCCHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]