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The map label for this gene is malR [H]

Identifier: 138894289

GI number: 138894289

Start: 683232

End: 684251

Strand: Direct

Name: malR [H]

Synonym: GTNG_0615

Alternate gene names: 138894289

Gene position: 683232-684251 (Clockwise)

Preceding gene: 138894288

Following gene: 138894290

Centisome position: 19.24

GC content: 52.65

Gene sequence:

>1020_bases
ATGACCGTTACGATTAAAGACGTCGCCAAACGAGCCAATGTCGCGCCGTCGACCGTCTCGCGCGTGATTGCCGATAGCCC
GCGCATCAGTGAGAAAACAAAGCAACGGGTGCGCGAGGCAATGAAAGAGCTTGGCTACCATCCAAATTTTATTGCCCGCA
GCCTCGCAAGCCAAGCGACGCAAGTGATCGGCATCGTCATGCCAAGCTCAGCTGATCAGGCGCTGCAAAACCCGTTTTTC
CCGGAAGTGATCCGCGGCATCAGCAAAGCTGCCCATGAAAAACGGTACGCCTTGCAAATGTCAACCGGGGAAAAAGAAAG
CGACATTTACGAACGGGTGATCGAGATGTTGCAAGGGCGGCGTGTTGACGGAGTGATTTTGCTTTATTCGCGGCAGAACG
ACAAGTTAATGAAATACTTGCAAAAACATGGCTTCCCGTTCGTTGTCATTGGAAAACCGCACCAAAAAGCGGAACAAGTG
ACCCATGTCGATAACGACAACGTCCAAGCTGGAAAAGATGCCACCAACTATTTAATCGACCATGGCCATGAGCGCATCGC
TTTTGTCGGTGGCAATCCACAATATTTTGTGACCGCCGACCGTCAAGAAGGCTATGAAGAGGCGCTGCGTGAAGCTGGAC
TGTTGTACCGACCGGAATACGTCGTTCATGAAGAGTTTTTGCAAGAAGGCGGCCGCGAGGCAATGAAGGAGCTGCTTTCT
CTAGCCGAGCCGCCGACCGGGCTTGTCGTTGCTGATGACCTCATGGCGCTCGGGATGGTCAAAACGCTCGATGAAATTGG
TCTTCGCGTTCCGGAAGATGTGTCGATCGTCAGCTTCAACAACACCTTGCTCGCCGAAATGTCGCGCCCGCCGTTGACTT
CCGTCGATATTGGCATCTTCCAACTCGGCTATGAAGCGGCGAAAAGTTTAATCGAAAAAGTCGAAAATCCAAATGAACCG
ATCAAGCGCATCATCATCCCACACCGGCTCGTTGAGCGGGGATCGTGTACGAGGCGGTGA

Upstream 100 bases:

>100_bases
ATCGTTGCAATGGTTGCGGTTTACGCACTATTTATCTTGTTTTTATACATGGTGAAAAAACGAACAAAACGGACAAATGA
ATAAAGAAAGGAGGTAGTAT

Downstream 100 bases:

>100_bases
ATAAGCTTTATCAAAAAGCAGCCGTTGTGGCTGCTTTTTGATTTGAAAAAGGAAATCAACGAGTTGGAGAGAAAAAAGAA
AACTAAACGAACACGGAGGT

Product: maltose operon transcriptional repressor

Products: NA

Alternate protein names: Maltose operon transcriptional repressor [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTVTIKDVAKRANVAPSTVSRVIADSPRISEKTKQRVREAMKELGYHPNFIARSLASQATQVIGIVMPSSADQALQNPFF
PEVIRGISKAAHEKRYALQMSTGEKESDIYERVIEMLQGRRVDGVILLYSRQNDKLMKYLQKHGFPFVVIGKPHQKAEQV
THVDNDNVQAGKDATNYLIDHGHERIAFVGGNPQYFVTADRQEGYEEALREAGLLYRPEYVVHEEFLQEGGREAMKELLS
LAEPPTGLVVADDLMALGMVKTLDEIGLRVPEDVSIVSFNNTLLAEMSRPPLTSVDIGIFQLGYEAAKSLIEKVENPNEP
IKRIIIPHRLVERGSCTRR

Sequences:

>Translated_339_residues
MTVTIKDVAKRANVAPSTVSRVIADSPRISEKTKQRVREAMKELGYHPNFIARSLASQATQVIGIVMPSSADQALQNPFF
PEVIRGISKAAHEKRYALQMSTGEKESDIYERVIEMLQGRRVDGVILLYSRQNDKLMKYLQKHGFPFVVIGKPHQKAEQV
THVDNDNVQAGKDATNYLIDHGHERIAFVGGNPQYFVTADRQEGYEEALREAGLLYRPEYVVHEEFLQEGGREAMKELLS
LAEPPTGLVVADDLMALGMVKTLDEIGLRVPEDVSIVSFNNTLLAEMSRPPLTSVDIGIFQLGYEAAKSLIEKVENPNEP
IKRIIIPHRLVERGSCTRR
>Mature_338_residues
TVTIKDVAKRANVAPSTVSRVIADSPRISEKTKQRVREAMKELGYHPNFIARSLASQATQVIGIVMPSSADQALQNPFFP
EVIRGISKAAHEKRYALQMSTGEKESDIYERVIEMLQGRRVDGVILLYSRQNDKLMKYLQKHGFPFVVIGKPHQKAEQVT
HVDNDNVQAGKDATNYLIDHGHERIAFVGGNPQYFVTADRQEGYEEALREAGLLYRPEYVVHEEFLQEGGREAMKELLSL
AEPPTGLVVADDLMALGMVKTLDEIGLRVPEDVSIVSFNNTLLAEMSRPPLTSVDIGIFQLGYEAAKSLIEKVENPNEPI
KRIIIPHRLVERGSCTRR

Specific function: Transcriptional repressor of the maltosaccharide utilization operons malxCD and malMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=333, Percent_Identity=31.8318318318318, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=33.3333333333333, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=33.5329341317365, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787580, Length=328, Percent_Identity=27.7439024390244, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789068, Length=313, Percent_Identity=30.9904153354633, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789202, Length=335, Percent_Identity=31.9402985074627, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787906, Length=339, Percent_Identity=27.7286135693215, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788474, Length=345, Percent_Identity=26.9565217391304, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI48994940, Length=313, Percent_Identity=26.8370607028754, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786540, Length=336, Percent_Identity=27.0833333333333, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789456, Length=339, Percent_Identity=25.9587020648968, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=25.9375, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=26.7477203647416, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786268, Length=350, Percent_Identity=24.2857142857143, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789993, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37990; Mature: 37859

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTIKDVAKRANVAPSTVSRVIADSPRISEKTKQRVREAMKELGYHPNFIARSLASQAT
CEEEHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QVIGIVMPSSADQALQNPFFPEVIRGISKAAHEKRYALQMSTGEKESDIYERVIEMLQGR
HHEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCC
RVDGVILLYSRQNDKLMKYLQKHGFPFVVIGKPHQKAEQVTHVDNDNVQAGKDATNYLID
CCCCEEEEEECCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
HGHERIAFVGGNPQYFVTADRQEGYEEALREAGLLYRPEYVVHEEFLQEGGREAMKELLS
CCCCEEEEECCCCCEEEECCHHCCHHHHHHHCCCEECCHHHHHHHHHHHCCHHHHHHHHH
LAEPPTGLVVADDLMALGMVKTLDEIGLRVPEDVSIVSFNNTLLAEMSRPPLTSVDIGIF
HCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCCCCCCHHHH
QLGYEAAKSLIEKVENPNEPIKRIIIPHRLVERGSCTRR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVTIKDVAKRANVAPSTVSRVIADSPRISEKTKQRVREAMKELGYHPNFIARSLASQAT
EEEHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QVIGIVMPSSADQALQNPFFPEVIRGISKAAHEKRYALQMSTGEKESDIYERVIEMLQGR
HHEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCC
RVDGVILLYSRQNDKLMKYLQKHGFPFVVIGKPHQKAEQVTHVDNDNVQAGKDATNYLID
CCCCEEEEEECCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCHHHHHHH
HGHERIAFVGGNPQYFVTADRQEGYEEALREAGLLYRPEYVVHEEFLQEGGREAMKELLS
CCCCEEEEECCCCCEEEECCHHCCHHHHHHHCCCEECCHHHHHHHHHHHCCHHHHHHHHH
LAEPPTGLVVADDLMALGMVKTLDEIGLRVPEDVSIVSFNNTLLAEMSRPPLTSVDIGIF
HCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHCCCCCCCCCCHHHH
QLGYEAAKSLIEKVENPNEPIKRIIIPHRLVERGSCTRR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]