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The map label for this gene is malZ [C]

Identifier: 138894288

GI number: 138894288

Start: 681680

End: 683215

Strand: Direct

Name: malZ [C]

Synonym: GTNG_0614

Alternate gene names: 138894288

Gene position: 681680-683215 (Clockwise)

Preceding gene: 138894287

Following gene: 138894289

Centisome position: 19.2

GC content: 46.61

Gene sequence:

>1536_bases
ATGGGGAACCGGCTTTTTATGCTGTTCATCCTTCCGTTCCTTCTTTTTTATGCCATGCCGGTTGCGGCGGCGGAAAAAGA
AGAACGGACGTGGCAAGACGAAGCGATTTATTTTATTATGGTCGATCGTTTTAACAACATGGATTCAACGAACGACCAAG
ACGTCAATGTCAATGATCCAAAAGGGTATTTTGGCGGTGACTTAAAAGGGGTGACAGCGAAGCTCGATTATATTAAAGAA
ATGGGCTTCACTGCCATTTGGCTGACTCCCATTTTTAAAAACAGGCCGGGCGGCTATCATGGCTATTGGATCGAGGACTT
TTACGAAGTCGACCCGCATTTTGGCACGCTTGATGACCTCAAGACGCTCGTCAAAGAGGCGCATAAGCGCGATATGAAAG
TGATTTTGGATTTCGTGGCTAACCATGTCGGCTACGACCATCCGTGGCTTCATGACCCGGCGAAAAAAGATTGGTTCCAT
CCGAAGAAAGAGATTTTCGACTGGAACAGCCAAGAGCAGGTGGAAAACGGTTGGGTGTATGGACTTCCCGATTTGGCGCA
GGAAAATCCGGAAGTAAAAAACTATTTAATTGACGCAGCCAAATGGTGGATTAAAGAAACCGACATTGACGGTTACCGAC
TCGACATGGTACGCCATGTGCCGAAATCGTTCTGGCAAGAGTTTGCGAAAGAAGTGAAAGCGGTAAAAAAAGACTTTTTT
CTCCTCGGCGAAGTGTGGAGTGATGATCCGCGCTATATCGCTGATTACGGAAAGTATGGCATCGACGGGTTTGTCGATTA
CCCGCTGTACGGTGCGGTGAAGCAGTCTCTTGCCAAACGTGATGCATCGCTTCGGCCGCTCTATGATGTATGGGAGTATA
ACAAGACATTTTACGACCGCCCGTATTTGCTTGGATCATTTTTGGACAACCATGATAACGTCCGATTTACGAAACTCGTC
ATTGATCATCGGAACAATCCGATTTCACGCATGAAAGTAGCGATGACGTATTTGTTCACTGCGCCGGGCATTCCGATTAT
GTACTACGGAACAGAAATTGCGATGACTGGAGGTCCTGATCCGGACAATCGCCGCCTGATGGACTTCCGTGCCGATCCAG
AAATCATCGATTATTTAAAGAAAGTGGGCCCGCTCCGCCAACAGTTGCCATCATTGCGGCGCGGCGATTTTACGTTGTTG
TATGAACAAGACGGCATGGCGGTGTTTAAACGCCAATACAAAGACGAAACGACGGTCATTGCCATTAACAACACGAGTGA
AACGAAGCACGTTCATCTGACGAACGAACAGCTGCCGAAAAACAAGGAATTGCGTGGCTTTTTGCTCGATGACCTCGTCC
GTGGCGATGAGGATGGCTATGATATTGTCTTGGATCGTGAAACAGCAGAAGTGTACAAATTACGGAACAAAACGGGAGTT
AACGTGCCGTTTATCGTTGCAATGGTTGCGGTTTACGCACTATTTATCTTGTTTTTATACATGGTGAAAAAACGAACAAA
ACGGACAAATGAATAA

Upstream 100 bases:

>100_bases
TTAACAGCGGGTGGCACAAAAGGGTAAGAATCGCTATCATAAATAGTGGGCTTACCCGTTTCCAAACAGAAAAAATAGAC
AGTAAAGGAGGGAAACGGAA

Downstream 100 bases:

>100_bases
AGAAAGGAGGTAGTATATGACCGTTACGATTAAAGACGTCGCCAAACGAGCCAATGTCGCGCCGTCGACCGTCTCGCGCG
TGATTGCCGATAGCCCGCGC

Product: alpha-amylase family protein

Products: NA

Alternate protein names: Beta-amylase; Alpha-amylase [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MGNRLFMLFILPFLLFYAMPVAAAEKEERTWQDEAIYFIMVDRFNNMDSTNDQDVNVNDPKGYFGGDLKGVTAKLDYIKE
MGFTAIWLTPIFKNRPGGYHGYWIEDFYEVDPHFGTLDDLKTLVKEAHKRDMKVILDFVANHVGYDHPWLHDPAKKDWFH
PKKEIFDWNSQEQVENGWVYGLPDLAQENPEVKNYLIDAAKWWIKETDIDGYRLDMVRHVPKSFWQEFAKEVKAVKKDFF
LLGEVWSDDPRYIADYGKYGIDGFVDYPLYGAVKQSLAKRDASLRPLYDVWEYNKTFYDRPYLLGSFLDNHDNVRFTKLV
IDHRNNPISRMKVAMTYLFTAPGIPIMYYGTEIAMTGGPDPDNRRLMDFRADPEIIDYLKKVGPLRQQLPSLRRGDFTLL
YEQDGMAVFKRQYKDETTVIAINNTSETKHVHLTNEQLPKNKELRGFLLDDLVRGDEDGYDIVLDRETAEVYKLRNKTGV
NVPFIVAMVAVYALFILFLYMVKKRTKRTNE

Sequences:

>Translated_511_residues
MGNRLFMLFILPFLLFYAMPVAAAEKEERTWQDEAIYFIMVDRFNNMDSTNDQDVNVNDPKGYFGGDLKGVTAKLDYIKE
MGFTAIWLTPIFKNRPGGYHGYWIEDFYEVDPHFGTLDDLKTLVKEAHKRDMKVILDFVANHVGYDHPWLHDPAKKDWFH
PKKEIFDWNSQEQVENGWVYGLPDLAQENPEVKNYLIDAAKWWIKETDIDGYRLDMVRHVPKSFWQEFAKEVKAVKKDFF
LLGEVWSDDPRYIADYGKYGIDGFVDYPLYGAVKQSLAKRDASLRPLYDVWEYNKTFYDRPYLLGSFLDNHDNVRFTKLV
IDHRNNPISRMKVAMTYLFTAPGIPIMYYGTEIAMTGGPDPDNRRLMDFRADPEIIDYLKKVGPLRQQLPSLRRGDFTLL
YEQDGMAVFKRQYKDETTVIAINNTSETKHVHLTNEQLPKNKELRGFLLDDLVRGDEDGYDIVLDRETAEVYKLRNKTGV
NVPFIVAMVAVYALFILFLYMVKKRTKRTNE
>Mature_510_residues
GNRLFMLFILPFLLFYAMPVAAAEKEERTWQDEAIYFIMVDRFNNMDSTNDQDVNVNDPKGYFGGDLKGVTAKLDYIKEM
GFTAIWLTPIFKNRPGGYHGYWIEDFYEVDPHFGTLDDLKTLVKEAHKRDMKVILDFVANHVGYDHPWLHDPAKKDWFHP
KKEIFDWNSQEQVENGWVYGLPDLAQENPEVKNYLIDAAKWWIKETDIDGYRLDMVRHVPKSFWQEFAKEVKAVKKDFFL
LGEVWSDDPRYIADYGKYGIDGFVDYPLYGAVKQSLAKRDASLRPLYDVWEYNKTFYDRPYLLGSFLDNHDNVRFTKLVI
DHRNNPISRMKVAMTYLFTAPGIPIMYYGTEIAMTGGPDPDNRRLMDFRADPEIIDYLKKVGPLRQQLPSLRRGDFTLLY
EQDGMAVFKRQYKDETTVIAINNTSETKHVHLTNEQLPKNKELRGFLLDDLVRGDEDGYDIVLDRETAEVYKLRNKTGVN
VPFIVAMVAVYALFILFLYMVKKRTKRTNE

Specific function: The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=215, Percent_Identity=29.3023255813954, Blast_Score=87, Evalue=5e-17,
Organism=Escherichia coli, GI1786604, Length=404, Percent_Identity=28.7128712871287, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1790687, Length=399, Percent_Identity=27.8195488721804, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789995, Length=133, Percent_Identity=35.3383458646617, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32565753, Length=155, Percent_Identity=29.6774193548387, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322245, Length=218, Percent_Identity=32.1100917431193, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322241, Length=229, Percent_Identity=30.5676855895196, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322021, Length=229, Percent_Identity=30.5676855895196, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324416, Length=229, Percent_Identity=30.5676855895196, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321726, Length=229, Percent_Identity=29.6943231441048, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319776, Length=144, Percent_Identity=37.5, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321731, Length=144, Percent_Identity=37.5, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24586587, Length=184, Percent_Identity=35.8695652173913, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24586599, Length=225, Percent_Identity=29.7777777777778, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221330053, Length=181, Percent_Identity=32.0441988950276, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24586593, Length=217, Percent_Identity=32.7188940092166, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24583745, Length=218, Percent_Identity=29.8165137614679, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45549022, Length=184, Percent_Identity=32.0652173913043, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24586597, Length=188, Percent_Identity=31.9148936170213, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24586591, Length=190, Percent_Identity=33.6842105263158, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586589, Length=189, Percent_Identity=33.8624338624339, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24583747, Length=190, Percent_Identity=32.1052631578947, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583749, Length=190, Percent_Identity=32.1052631578947, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR005085
- InterPro:   IPR008985
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR001554
- InterPro:   IPR018238
- InterPro:   IPR000125
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF03423 CBM_25; PF01373 Glyco_hydro_14 [H]

EC number: =3.2.1.2; =3.2.1.1 [H]

Molecular weight: Translated: 59894; Mature: 59763

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLFMLFILPFLLFYAMPVAAAEKEERTWQDEAIYFIMVDRFNNMDSTNDQDVNVNDP
CCCCEEHHHHHHHHHHHHCCHHHCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
KGYFGGDLKGVTAKLDYIKEMGFTAIWLTPIFKNRPGGYHGYWIEDFYEVDPHFGTLDDL
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHEECCCCCCCHHHH
KTLVKEAHKRDMKVILDFVANHVGYDHPWLHDPAKKDWFHPKKEIFDWNSQEQVENGWVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHCCCEE
GLPDLAQENPEVKNYLIDAAKWWIKETDIDGYRLDMVRHVPKSFWQEFAKEVKAVKKDFF
CCCHHHHCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGEVWSDDPRYIADYGKYGIDGFVDYPLYGAVKQSLAKRDASLRPLYDVWEYNKTFYDR
EEHHHCCCCCCHHHHHCCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCC
PYLLGSFLDNHDNVRFTKLVIDHRNNPISRMKVAMTYLFTAPGIPIMYYGTEIAMTGGPD
CHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCC
PDNRRLMDFRADPEIIDYLKKVGPLRQQLPSLRRGDFTLLYEQDGMAVFKRQYKDETTVI
CCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEE
AINNTSETKHVHLTNEQLPKNKELRGFLLDDLVRGDEDGYDIVLDRETAEVYKLRNKTGV
EEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCC
NVPFIVAMVAVYALFILFLYMVKKRTKRTNE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GNRLFMLFILPFLLFYAMPVAAAEKEERTWQDEAIYFIMVDRFNNMDSTNDQDVNVNDP
CCCEEHHHHHHHHHHHHCCHHHCCHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
KGYFGGDLKGVTAKLDYIKEMGFTAIWLTPIFKNRPGGYHGYWIEDFYEVDPHFGTLDDL
CCCCCCCCCHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHEECCCCCCCHHHH
KTLVKEAHKRDMKVILDFVANHVGYDHPWLHDPAKKDWFHPKKEIFDWNSQEQVENGWVY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHCCCEE
GLPDLAQENPEVKNYLIDAAKWWIKETDIDGYRLDMVRHVPKSFWQEFAKEVKAVKKDFF
CCCHHHHCCCHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGEVWSDDPRYIADYGKYGIDGFVDYPLYGAVKQSLAKRDASLRPLYDVWEYNKTFYDR
EEHHHCCCCCCHHHHHCCCCCCCEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHCCC
PYLLGSFLDNHDNVRFTKLVIDHRNNPISRMKVAMTYLFTAPGIPIMYYGTEIAMTGGPD
CHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCC
PDNRRLMDFRADPEIIDYLKKVGPLRQQLPSLRRGDFTLLYEQDGMAVFKRQYKDETTVI
CCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEE
AINNTSETKHVHLTNEQLPKNKELRGFLLDDLVRGDEDGYDIVLDRETAEVYKLRNKTGV
EEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCCC
NVPFIVAMVAVYALFILFLYMVKKRTKRTNE
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2435707; 2464578; 2438660; 1827035 [H]