Click here to switch to the map view.

The map label for this gene is stc [H]

Identifier: 138894290

GI number: 138894290

Start: 684367

End: 686292

Strand: Direct

Name: stc [H]

Synonym: GTNG_0616

Alternate gene names: 138894290

Gene position: 684367-686292 (Clockwise)

Preceding gene: 138894289

Following gene: 138894291

Centisome position: 19.28

GC content: 43.46

Gene sequence:

>1926_bases
ATGAATCGCGAGCGGGTAAAATACATGTGGGAAAAGTTCGTATTTCATAACGAGCTTGCTCCTGATTTGCCGCCCATGAT
TCGAGACTCTTGGCTTCGGTCGAAAAAAGCGATGGTTGATCCGTTTCGTCCATATGGATGGATTAAGGAAATTGACAATG
AAAAGTATTGCTCATTGATTGATTGGTCACTGCCGCTAATGGAAGGATTGTATTCAATTGTAAAAGGATCCGGATTTTTG
GTGATTCTGTGCAATGAAAGCGGGCAGTTGCTTTTGTCGATTGGTGACAGCGAGCCCTTGGCAAGGGCGGAAGAAATCGG
GTTTATCGCTGGGGCGGATTGGAGCGAGCAAGTGATGGGAACCAACGCCATTGGCACTTCGATTGCCATCGACCGTCCTG
TGCAAATATTTGCCGAGGAACATTATACAAAAATATGTCAATCATGGACGTGTTCCGCTGCCCCCATCCATGACCCTGAC
GGTAGAATCATTGGTGTACTGAATATGTCAGGACCCTATGAAAAAGTGCATCCTCATACATTAGGGATGGTTGTATCGGC
CGTAAAGGCGATTGAGTATCAGTTAAAATTACATGAGAATACCGAAAAAAACGTGATGATGCAACGGTTTTTGGAAGCGA
CCACGAACAATATGAAAGAGGGCATTTTAATCATCGACTGCGTTGGGAAGATCGTAAAAGCGAACAATCAATTAAAAAAA
CTGTTCCGCTTACCACAGTTGCAACTGGAAGAAAAAACGATTGATGATATTTTTAGTGATTCCTCTATCTGTTCAAATCA
TCCGCTGCATTTGCAAAATCAAGAACTGCATCTGAGTGTCAAGCCCTCCAACGCGGTGCATCATGTGCTAGTTGACAAGA
TTCCCATTTACGAGAAAAAAGAACGAATCGGATCGATGATCATTGTAAAAGAAATTGAAAAAGTGCGCCAGTTTGTTAAC
CACCTATCGGGAAATCAAGCCAAAATCACGTTTGCAGATATAATTGGGCAACACCCATGCTTCATCCAGAAAATGAACGA
AGCAAGACTTGCCGCGGCGACCGATTCAAATGTGTTAATATTAGGAGAAAGCGGCACTGGAAAAGAAATGGTGGCTCAAG
CGATTCATAACGAGAGTAAGCGAAGAAACAAACCGTTTATTGCCATCAACTGTGGAGGAATACCACGTGATCTTCTTGGA
AGCGAATTGTTTGGGTATGTAGACGGGGCGTTTACAGGAGCGAAAAAAGGGGGAAGCGCCGGGAAGTTTGAGCTCGCTAA
TGGGGGAACGCTTTTTTTGGATGAGATTGGCGAAATGTCTTTGGAAATGCAAGTGTTGCTTTTGCGTGTCATCCAAGAAA
AGGAAGTAATGAGAATTGGTGGACACAAAGTAACCCCTGTTGATGTAAGAATCATCGCAGCGACCAACAAAGACCTTCGC
CGAGAAGTGCAAAAAGGTAGCTTTCGTGAAGACTTATTTTTCCGGTTGAATGTCATGCCGATTGTTTTGCCGCCGCTTCG
GGAAAGGAAAGAAGATATTCCGCTTCTTGTCCGCTATTTTATTGACAAACTCGCTCATAAACGAAATAAACCGTTTCCCG
AAATACGATCTGATTTTTTAGAGGTGCTTATGCAATACGATTGGCCTGGAAATATCCGTGAATTACAAAATATAATTGAG
CGAGTGCTGAATCACAGTACAAAGCCGATTTTGACAGCAGCTGACTTGCCGGAAGAAATCTTTCATCCTCCTTGCTCGTT
TCAAGTTAGGGAGAGCATAGACATCTCCCGGAATGGAATAAAAAAGCAAGCCATCATCGAAGCGTTAAAGCGGTGCAATG
GCAATATTTCCAAAGCAGCCCGTTATTTAGGCATATCGAGAAGCACGTTTTATCGACAAATGGACAAGTGGAATATCCGC
TACTGA

Upstream 100 bases:

>100_bases
AAGCAGCCGTTGTGGCTGCTTTTTGATTTGAAAAAGGAAATCAACGAGTTGGAGAGAAAAAAGAAAACTAAACGAACACG
GAGGTGAACATAGGGTGCCG

Downstream 100 bases:

>100_bases
CTGTTTCATTATGTATCAAAGTGTAGCGACAAAGTGAAACAAAATGAAACACTTTGTCGCATTTTTTGTTTAGGCTAGAT
TAAAAAGGAAACTTGGGACG

Product: putative regulator of acetoin metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MNRERVKYMWEKFVFHNELAPDLPPMIRDSWLRSKKAMVDPFRPYGWIKEIDNEKYCSLIDWSLPLMEGLYSIVKGSGFL
VILCNESGQLLLSIGDSEPLARAEEIGFIAGADWSEQVMGTNAIGTSIAIDRPVQIFAEEHYTKICQSWTCSAAPIHDPD
GRIIGVLNMSGPYEKVHPHTLGMVVSAVKAIEYQLKLHENTEKNVMMQRFLEATTNNMKEGILIIDCVGKIVKANNQLKK
LFRLPQLQLEEKTIDDIFSDSSICSNHPLHLQNQELHLSVKPSNAVHHVLVDKIPIYEKKERIGSMIIVKEIEKVRQFVN
HLSGNQAKITFADIIGQHPCFIQKMNEARLAAATDSNVLILGESGTGKEMVAQAIHNESKRRNKPFIAINCGGIPRDLLG
SELFGYVDGAFTGAKKGGSAGKFELANGGTLFLDEIGEMSLEMQVLLLRVIQEKEVMRIGGHKVTPVDVRIIAATNKDLR
REVQKGSFREDLFFRLNVMPIVLPPLRERKEDIPLLVRYFIDKLAHKRNKPFPEIRSDFLEVLMQYDWPGNIRELQNIIE
RVLNHSTKPILTAADLPEEIFHPPCSFQVRESIDISRNGIKKQAIIEALKRCNGNISKAARYLGISRSTFYRQMDKWNIR
Y

Sequences:

>Translated_641_residues
MNRERVKYMWEKFVFHNELAPDLPPMIRDSWLRSKKAMVDPFRPYGWIKEIDNEKYCSLIDWSLPLMEGLYSIVKGSGFL
VILCNESGQLLLSIGDSEPLARAEEIGFIAGADWSEQVMGTNAIGTSIAIDRPVQIFAEEHYTKICQSWTCSAAPIHDPD
GRIIGVLNMSGPYEKVHPHTLGMVVSAVKAIEYQLKLHENTEKNVMMQRFLEATTNNMKEGILIIDCVGKIVKANNQLKK
LFRLPQLQLEEKTIDDIFSDSSICSNHPLHLQNQELHLSVKPSNAVHHVLVDKIPIYEKKERIGSMIIVKEIEKVRQFVN
HLSGNQAKITFADIIGQHPCFIQKMNEARLAAATDSNVLILGESGTGKEMVAQAIHNESKRRNKPFIAINCGGIPRDLLG
SELFGYVDGAFTGAKKGGSAGKFELANGGTLFLDEIGEMSLEMQVLLLRVIQEKEVMRIGGHKVTPVDVRIIAATNKDLR
REVQKGSFREDLFFRLNVMPIVLPPLRERKEDIPLLVRYFIDKLAHKRNKPFPEIRSDFLEVLMQYDWPGNIRELQNIIE
RVLNHSTKPILTAADLPEEIFHPPCSFQVRESIDISRNGIKKQAIIEALKRCNGNISKAARYLGISRSTFYRQMDKWNIR
Y
>Mature_641_residues
MNRERVKYMWEKFVFHNELAPDLPPMIRDSWLRSKKAMVDPFRPYGWIKEIDNEKYCSLIDWSLPLMEGLYSIVKGSGFL
VILCNESGQLLLSIGDSEPLARAEEIGFIAGADWSEQVMGTNAIGTSIAIDRPVQIFAEEHYTKICQSWTCSAAPIHDPD
GRIIGVLNMSGPYEKVHPHTLGMVVSAVKAIEYQLKLHENTEKNVMMQRFLEATTNNMKEGILIIDCVGKIVKANNQLKK
LFRLPQLQLEEKTIDDIFSDSSICSNHPLHLQNQELHLSVKPSNAVHHVLVDKIPIYEKKERIGSMIIVKEIEKVRQFVN
HLSGNQAKITFADIIGQHPCFIQKMNEARLAAATDSNVLILGESGTGKEMVAQAIHNESKRRNKPFIAINCGGIPRDLLG
SELFGYVDGAFTGAKKGGSAGKFELANGGTLFLDEIGEMSLEMQVLLLRVIQEKEVMRIGGHKVTPVDVRIIAATNKDLR
REVQKGSFREDLFFRLNVMPIVLPPLRERKEDIPLLVRYFIDKLAHKRNKPFPEIRSDFLEVLMQYDWPGNIRELQNIIE
RVLNHSTKPILTAADLPEEIFHPPCSFQVRESIDISRNGIKKQAIIEALKRCNGNISKAARYLGISRSTFYRQMDKWNIR
Y

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=339, Percent_Identity=42.4778761061947, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=44.8844884488449, Blast_Score=269, Evalue=5e-73,
Organism=Escherichia coli, GI87082117, Length=346, Percent_Identity=42.1965317919075, Blast_Score=268, Evalue=1e-72,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=45.0310559006211, Blast_Score=266, Evalue=4e-72,
Organism=Escherichia coli, GI1789233, Length=301, Percent_Identity=47.5083056478405, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1789087, Length=358, Percent_Identity=40.7821229050279, Blast_Score=259, Evalue=5e-70,
Organism=Escherichia coli, GI1788905, Length=307, Percent_Identity=42.671009771987, Blast_Score=251, Evalue=7e-68,
Organism=Escherichia coli, GI87081858, Length=645, Percent_Identity=27.5968992248062, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1790299, Length=326, Percent_Identity=40.1840490797546, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=40.8805031446541, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1787583, Length=367, Percent_Identity=34.6049046321526, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=324, Percent_Identity=37.962962962963, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1789828, Length=256, Percent_Identity=34.375, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72778; Mature: 72778

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRERVKYMWEKFVFHNELAPDLPPMIRDSWLRSKKAMVDPFRPYGWIKEIDNEKYCSLI
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEE
DWSLPLMEGLYSIVKGSGFLVILCNESGQLLLSIGDSEPLARAEEIGFIAGADWSEQVMG
CCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCHHHHHHCCEEECCCCHHHHHC
TNAIGTSIAIDRPVQIFAEEHYTKICQSWTCSAAPIHDPDGRIIGVLNMSGPYEKVHPHT
CCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCHH
LGMVVSAVKAIEYQLKLHENTEKNVMMQRFLEATTNNMKEGILIIDCVGKIVKANNQLKK
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCHHCCEEEEEHHHHHHHCCHHHHH
LFRLPQLQLEEKTIDDIFSDSSICSNHPLHLQNQELHLSVKPSNAVHHVLVDKIPIYEKK
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHCCCCCHHH
ERIGSMIIVKEIEKVRQFVNHLSGNQAKITFADIIGQHPCFIQKMNEARLAAATDSNVLI
HHHCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHCCHHEEEECCCCEEE
LGESGTGKEMVAQAIHNESKRRNKPFIAINCGGIPRDLLGSELFGYVDGAFTGAKKGGSA
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GKFELANGGTLFLDEIGEMSLEMQVLLLRVIQEKEVMRIGGHKVTPVDVRIIAATNKDLR
CEEEECCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCHHHH
REVQKGSFREDLFFRLNVMPIVLPPLRERKEDIPLLVRYFIDKLAHKRNKPFPEIRSDFL
HHHHCCCCHHHHEEEEECCEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EVLMQYDWPGNIRELQNIIERVLNHSTKPILTAADLPEEIFHPPCSFQVRESIDISRNGI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCEECCCCCCCCCCC
KKQAIIEALKRCNGNISKAARYLGISRSTFYRQMDKWNIRY
HHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRERVKYMWEKFVFHNELAPDLPPMIRDSWLRSKKAMVDPFRPYGWIKEIDNEKYCSLI
CCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEE
DWSLPLMEGLYSIVKGSGFLVILCNESGQLLLSIGDSEPLARAEEIGFIAGADWSEQVMG
CCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCHHHHHHCCEEECCCCHHHHHC
TNAIGTSIAIDRPVQIFAEEHYTKICQSWTCSAAPIHDPDGRIIGVLNMSGPYEKVHPHT
CCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCHH
LGMVVSAVKAIEYQLKLHENTEKNVMMQRFLEATTNNMKEGILIIDCVGKIVKANNQLKK
HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCHHCCEEEEEHHHHHHHCCHHHHH
LFRLPQLQLEEKTIDDIFSDSSICSNHPLHLQNQELHLSVKPSNAVHHVLVDKIPIYEKK
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHCCCCCHHH
ERIGSMIIVKEIEKVRQFVNHLSGNQAKITFADIIGQHPCFIQKMNEARLAAATDSNVLI
HHHCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHHCCHHEEEECCCCEEE
LGESGTGKEMVAQAIHNESKRRNKPFIAINCGGIPRDLLGSELFGYVDGAFTGAKKGGSA
EECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GKFELANGGTLFLDEIGEMSLEMQVLLLRVIQEKEVMRIGGHKVTPVDVRIIAATNKDLR
CEEEECCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEECCHHHH
REVQKGSFREDLFFRLNVMPIVLPPLRERKEDIPLLVRYFIDKLAHKRNKPFPEIRSDFL
HHHHCCCCHHHHEEEEECCEEECCCHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
EVLMQYDWPGNIRELQNIIERVLNHSTKPILTAADLPEEIFHPPCSFQVRESIDISRNGI
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCCCCEECCCCCCCCCCC
KKQAIIEALKRCNGNISKAARYLGISRSTFYRQMDKWNIRY
HHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA