Click here to switch to the map view.

The map label for this gene is fhuG [H]

Identifier: 138893848

GI number: 138893848

Start: 185093

End: 186082

Strand: Reverse

Name: fhuG [H]

Synonym: GTNG_0172

Alternate gene names: 138893848

Gene position: 186082-185093 (Counterclockwise)

Preceding gene: 138893849

Following gene: 138893843

Centisome position: 5.24

GC content: 52.93

Gene sequence:

>990_bases
ATGAGAATGCGCATCACGATCGTATTGGTGCTGCTTTTCCTGCTCATTACTGCAACAGTTGCCATCGCGTTAGGTACTGG
AGAAGCGCCACTCTCATATGGCCGCATTATTCCAACGTTATTTGGCTACGGTTCGATGCAAGAAGAGTTTATTTTATTTT
CTCTCCGTCTGCCGCGCATCGTGATTACGTTGCTCGCCGGGATGGCGCTCGCCTTATCAGGAGCGATGTTGCAAGGCATC
ACACGAAATGAGCTGGCCGATCCAGGTATATTAGGCATCAACGCCGGAGCTGGCGCCGGCGTCGCTTTATTCTTTTTATT
TTTCCCGATTGAAGCAGGAACATTTCTTTACGCCTTGCCGCTCGTCGCCTTAGTCGGAGCGCTGTTGACGGCAGCGGCCA
TTTACGCCGTTTCCTACAATAAAACAACCGGGCTGCAACCGGTATCGTTCGTGCTCACTGGGGTCGGGTTTTCCATGGCG
CTCTCCGGGCTCATGATCGTTCTCATTTCCGCCGCTGATCGGACAAAAGTTGATTTTATTGCTAGATGGCTTTCCGGAAA
CATTTGGGGCGATGATTGGCCGTTCATTTTCGCCATGCTGCCGTGGCTTGTCATCGGTGCATTCATCGGCCTTTACCGGT
CGAAACGGTTAAACCTTTTGCATTTAGGTGATCCGGTGGCCATTGGTGTCGGCGTCCATGTTCGCCGCGAGCGGCTCGTA
CTGATGGCAACAGCAGTCGCTGTCGCCGCAGCTGCCGTCGCTGTAACTGGAGGCATCTCCTTTATCGGATTGATGGCGCC
GCATATCGCCAAAATGATCGTCGGGCCTCGTCATGAGCGATCCATTCCGACCTCGATGCTCATCGGTGGCTGGCTGTTGC
TCACGGCTGACACGATTGGGCGCAATGCCCTTGCCGAACCGCTCCCAGCAGGAGTCGTTGTGTCATTAATCGGTGCACCG
TACTTCATTTATTTATTATTGAAACGTTAA

Upstream 100 bases:

>100_bases
CGATTCACGCCCCGTTTGAAACACCTGTGGCAGCCATCGTTGCTGTGATCGGTTTGCCGTTTTTCCTGTTTGTCGTGCGG
AAAAAAGGGAGGGGCTTTGA

Downstream 100 bases:

>100_bases
TCCTTTTGACGGACATGGTGAACCAAAGATTGCGGCGAAGCTCGTTTAATTGCCTTCATCTTTGTCTCGACTCCTGTTTC
CTTTGAAGCAGGAGCTTCCT

Product: Iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRMRITIVLVLLFLLITATVAIALGTGEAPLSYGRIIPTLFGYGSMQEEFILFSLRLPRIVITLLAGMALALSGAMLQGI
TRNELADPGILGINAGAGAGVALFFLFFPIEAGTFLYALPLVALVGALLTAAAIYAVSYNKTTGLQPVSFVLTGVGFSMA
LSGLMIVLISAADRTKVDFIARWLSGNIWGDDWPFIFAMLPWLVIGAFIGLYRSKRLNLLHLGDPVAIGVGVHVRRERLV
LMATAVAVAAAAVAVTGGISFIGLMAPHIAKMIVGPRHERSIPTSMLIGGWLLLTADTIGRNALAEPLPAGVVVSLIGAP
YFIYLLLKR

Sequences:

>Translated_329_residues
MRMRITIVLVLLFLLITATVAIALGTGEAPLSYGRIIPTLFGYGSMQEEFILFSLRLPRIVITLLAGMALALSGAMLQGI
TRNELADPGILGINAGAGAGVALFFLFFPIEAGTFLYALPLVALVGALLTAAAIYAVSYNKTTGLQPVSFVLTGVGFSMA
LSGLMIVLISAADRTKVDFIARWLSGNIWGDDWPFIFAMLPWLVIGAFIGLYRSKRLNLLHLGDPVAIGVGVHVRRERLV
LMATAVAVAAAAVAVTGGISFIGLMAPHIAKMIVGPRHERSIPTSMLIGGWLLLTADTIGRNALAEPLPAGVVVSLIGAP
YFIYLLLKR
>Mature_329_residues
MRMRITIVLVLLFLLITATVAIALGTGEAPLSYGRIIPTLFGYGSMQEEFILFSLRLPRIVITLLAGMALALSGAMLQGI
TRNELADPGILGINAGAGAGVALFFLFFPIEAGTFLYALPLVALVGALLTAAAIYAVSYNKTTGLQPVSFVLTGVGFSMA
LSGLMIVLISAADRTKVDFIARWLSGNIWGDDWPFIFAMLPWLVIGAFIGLYRSKRLNLLHLGDPVAIGVGVHVRRERLV
LMATAVAVAAAAVAVTGGISFIGLMAPHIAKMIVGPRHERSIPTSMLIGGWLLLTADTIGRNALAEPLPAGVVVSLIGAP
YFIYLLLKR

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=329, Percent_Identity=35.258358662614, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790741, Length=298, Percent_Identity=35.2348993288591, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786347, Length=301, Percent_Identity=35.2159468438538, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786804, Length=325, Percent_Identity=29.8461538461538, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=34.640522875817, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=33.8078291814947, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34886; Mature: 34886

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRITIVLVLLFLLITATVAIALGTGEAPLSYGRIIPTLFGYGSMQEEFILFSLRLPRI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHEEEHHHHHHH
VITLLAGMALALSGAMLQGITRNELADPGILGINAGAGAGVALFFLFFPIEAGTFLYALP
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
LVALVGALLTAAAIYAVSYNKTTGLQPVSFVLTGVGFSMALSGLMIVLISAADRTKVDFI
HHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
ARWLSGNIWGDDWPFIFAMLPWLVIGAFIGLYRSKRLNLLHLGDPVAIGVGVHVRRERLV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCEEHHHHHH
LMATAVAVAAAAVAVTGGISFIGLMAPHIAKMIVGPRHERSIPTSMLIGGWLLLTADTIG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEHHHC
RNALAEPLPAGVVVSLIGAPYFIYLLLKR
CCHHCCCCCHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MRMRITIVLVLLFLLITATVAIALGTGEAPLSYGRIIPTLFGYGSMQEEFILFSLRLPRI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHEEEHHHHHHH
VITLLAGMALALSGAMLQGITRNELADPGILGINAGAGAGVALFFLFFPIEAGTFLYALP
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHH
LVALVGALLTAAAIYAVSYNKTTGLQPVSFVLTGVGFSMALSGLMIVLISAADRTKVDFI
HHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHH
ARWLSGNIWGDDWPFIFAMLPWLVIGAFIGLYRSKRLNLLHLGDPVAIGVGVHVRRERLV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCCEEHHHHHH
LMATAVAVAAAAVAVTGGISFIGLMAPHIAKMIVGPRHERSIPTSMLIGGWLLLTADTIG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEEHHHC
RNALAEPLPAGVVVSLIGAPYFIYLLLKR
CCHHCCCCCHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]