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The map label for this gene is fhuB [H]

Identifier: 138893849

GI number: 138893849

Start: 186079

End: 187086

Strand: Reverse

Name: fhuB [H]

Synonym: GTNG_0173

Alternate gene names: 138893849

Gene position: 187086-186079 (Counterclockwise)

Preceding gene: 138893850

Following gene: 138893848

Centisome position: 5.27

GC content: 55.26

Gene sequence:

>1008_bases
ATGGAAGCAAACCGCCGGCTATGGCCGTTTCGTTATACGTTTCTCTTCTCTCTTGTCCTGCTGATGGCCATCTGGTTCGG
ATCCATGGCCATCGGCGTCGCTGATACAACATGGAGTGACGTATGGCGCGCACTCTTTTCCGATGAACAAGGCAAACAAC
TTGACTTGATTCGCGAGCTCCGTCTGCCGCGTGAAACGGCGGCTGCGATCGTTGGTGCGGGACTCGCGGTGGCCGGAGCG
ATCATGCAAGGAATGACGCGCAATCCGCTTGCCGATCCAGGGCTGCTTGGTCTCACTGCTGGAGCGAACACGGCATTGGC
GATGACGATGGCCTTTTTTCCTTCTGCTCATTATCTCATCATCACGGTCGCCTGTTTGCTTGGGGCGGCCGCCGGAGCGG
GGATGGTCTTTGGCATCGGCGCTGCCCGCAAAGGCGGTTTCTCACCGTTGCGCATCGTCTTAGCTGGCTCAGCTGTCTCA
GCACTTTTATTCGCGGCAGCTGAAGGAATCAGCCTTTATTTTCATATCTCGAAAGATGTCTCCATGTGGACGTCAGGCGG
GGTGGCCGGAACTTCATGGAAACAATTGTCGATCATCATTCCGCTCATTGTGATCGGGCTCACCATTGCCGTGTTGTATT
CGCGGCAACTGACGATCCTTAGTTTAAGTGAAGACGTCGCCGTTGGCGTCGGACAAAAAACAACCGCCGTCAAAGTGTGG
CTGTTTGTGGCCGTATTTTTCTTAACAGGAGCGTCCGTTGCCATTGCCGGCAACATCACCTTTATCGGTTTGATGATTCC
TCATCTCGTACGGAGGATCGCCGGCGCAGATTATCGGTTTGTCATCCCGTTGTCGGCCACAGTCGGCGCGATAGCCATGG
TGCTCGCCGATACGGCGGCCCGCACGATTCACGCCCCGTTTGAAACACCTGTGGCAGCCATCGTTGCTGTGATCGGTTTG
CCGTTTTTCCTGTTTGTCGTGCGGAAAAAAGGGAGGGGCTTTGAATGA

Upstream 100 bases:

>100_bases
TCTTTAAAAAGCATTTTTTAGGCCAATAATAATGATGAGACGGGGCGTTCACAAATAGTGAATGTCCCGTCCTTTCTTGT
GAAAAAGGGGGAAACCGCCG

Downstream 100 bases:

>100_bases
GAATGCGCATCACGATCGTATTGGTGCTGCTTTTCCTGCTCATTACTGCAACAGTTGCCATCGCGTTAGGTACTGGAGAA
GCGCCACTCTCATATGGCCG

Product: ferrichrome transport system permease FhuB

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MEANRRLWPFRYTFLFSLVLLMAIWFGSMAIGVADTTWSDVWRALFSDEQGKQLDLIRELRLPRETAAAIVGAGLAVAGA
IMQGMTRNPLADPGLLGLTAGANTALAMTMAFFPSAHYLIITVACLLGAAAGAGMVFGIGAARKGGFSPLRIVLAGSAVS
ALLFAAAEGISLYFHISKDVSMWTSGGVAGTSWKQLSIIIPLIVIGLTIAVLYSRQLTILSLSEDVAVGVGQKTTAVKVW
LFVAVFFLTGASVAIAGNITFIGLMIPHLVRRIAGADYRFVIPLSATVGAIAMVLADTAARTIHAPFETPVAAIVAVIGL
PFFLFVVRKKGRGFE

Sequences:

>Translated_335_residues
MEANRRLWPFRYTFLFSLVLLMAIWFGSMAIGVADTTWSDVWRALFSDEQGKQLDLIRELRLPRETAAAIVGAGLAVAGA
IMQGMTRNPLADPGLLGLTAGANTALAMTMAFFPSAHYLIITVACLLGAAAGAGMVFGIGAARKGGFSPLRIVLAGSAVS
ALLFAAAEGISLYFHISKDVSMWTSGGVAGTSWKQLSIIIPLIVIGLTIAVLYSRQLTILSLSEDVAVGVGQKTTAVKVW
LFVAVFFLTGASVAIAGNITFIGLMIPHLVRRIAGADYRFVIPLSATVGAIAMVLADTAARTIHAPFETPVAAIVAVIGL
PFFLFVVRKKGRGFE
>Mature_335_residues
MEANRRLWPFRYTFLFSLVLLMAIWFGSMAIGVADTTWSDVWRALFSDEQGKQLDLIRELRLPRETAAAIVGAGLAVAGA
IMQGMTRNPLADPGLLGLTAGANTALAMTMAFFPSAHYLIITVACLLGAAAGAGMVFGIGAARKGGFSPLRIVLAGSAVS
ALLFAAAEGISLYFHISKDVSMWTSGGVAGTSWKQLSIIIPLIVIGLTIAVLYSRQLTILSLSEDVAVGVGQKTTAVKVW
LFVAVFFLTGASVAIAGNITFIGLMIPHLVRRIAGADYRFVIPLSATVGAIAMVLADTAARTIHAPFETPVAAIVAVIGL
PFFLFVVRKKGRGFE

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=295, Percent_Identity=33.5593220338983, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786805, Length=308, Percent_Identity=35.3896103896104, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790741, Length=326, Percent_Identity=33.4355828220859, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786347, Length=291, Percent_Identity=33.6769759450172, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=36.2989323843416, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786804, Length=296, Percent_Identity=28.3783783783784, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35375; Mature: 35375

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEANRRLWPFRYTFLFSLVLLMAIWFGSMAIGVADTTWSDVWRALFSDEQGKQLDLIREL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
RLPRETAAAIVGAGLAVAGAIMQGMTRNPLADPGLLGLTAGANTALAMTMAFFPSAHYLI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCHHHH
ITVACLLGAAAGAGMVFGIGAARKGGFSPLRIVLAGSAVSALLFAAAEGISLYFHISKDV
HHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEEEEEEECCC
SMWTSGGVAGTSWKQLSIIIPLIVIGLTIAVLYSRQLTILSLSEDVAVGVGQKTTAVKVW
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECCCCCHHHHHHH
LFVAVFFLTGASVAIAGNITFIGLMIPHLVRRIAGADYRFVIPLSATVGAIAMVLADTAA
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
RTIHAPFETPVAAIVAVIGLPFFLFVVRKKGRGFE
HEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEANRRLWPFRYTFLFSLVLLMAIWFGSMAIGVADTTWSDVWRALFSDEQGKQLDLIREL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
RLPRETAAAIVGAGLAVAGAIMQGMTRNPLADPGLLGLTAGANTALAMTMAFFPSAHYLI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCHHHH
ITVACLLGAAAGAGMVFGIGAARKGGFSPLRIVLAGSAVSALLFAAAEGISLYFHISKDV
HHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHCCCEEEEEEECCC
SMWTSGGVAGTSWKQLSIIIPLIVIGLTIAVLYSRQLTILSLSEDVAVGVGQKTTAVKVW
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEECCCCCHHHHHHH
LFVAVFFLTGASVAIAGNITFIGLMIPHLVRRIAGADYRFVIPLSATVGAIAMVLADTAA
HHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
RTIHAPFETPVAAIVAVIGLPFFLFVVRKKGRGFE
HEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]