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The map label for this gene is ptmB [H]

Identifier: 126696751

GI number: 126696751

Start: 1179891

End: 1180574

Strand: Reverse

Name: ptmB [H]

Synonym: P9301_14131

Alternate gene names: 126696751

Gene position: 1180574-1179891 (Counterclockwise)

Preceding gene: 126696752

Following gene: 126696750

Centisome position: 71.9

GC content: 29.68

Gene sequence:

>684_bases
ATGAGTAAAGACTTTTACGCCTTTATTTTTGCAAGAGGTGGTTCAAAAGGAATAACAAAAAAAAACCTTAGAAAAATAAA
TGGTATTTCTTTGGTAAGAAGAAGTATTGATTTGGCATTACAACTTGATAATGTTTTAAAAATATTTTTATCAACAGATT
CACAAGAGATAGCAAATGAAGTAAATTCCTTAGATGTAGAAGTGATAAAAAGACCTTATGAGTTAGCTAAAGACGAAACA
AGTGAAATTTTAGCTTGGAAACATGCTATTAATGTGGTCGAAGAAAAGTTTGGTAGTTTTGATAAGTTTGTCTCAATTCC
ACCAACATCTCCCTTGAGGAGCTTAGAAGACGTAAAAAATATTATGTTTTTATTAAATGCTAAATTTGACTTAACATTAG
GAATAACAAAGTCAAAACGAAATCCCTGGTTTAATATGGTCAAAAAATCTGAAGGAAATCAAGTAACAAAAATCTTTAAT
GATAAGAGTTTTTCAAGAAGACAAGATGCTCCATTAACATTTGATTTGACAACAGTTGCCTATGCTGCGCATACAAGTTA
CGTTATCAATTCAAAGAATTTATTAGATGGAGTTATTGGAGGCTTAGAAATACCAGAAGAAAGATCTTTAGATATTGATA
CGGAAATTGATTTAAAAATGGCCGAATTCTTTTTAAATCAGTGA

Upstream 100 bases:

>100_bases
TAATAAATAAAACAAATTCTTCAGAATCTATTGGGTGTTCACTAACAGAAGGGATATCTGTTTTAGAACTCATAAAATTA
ATAAATAACAAATGTAACTT

Downstream 100 bases:

>100_bases
TTTAATATGGAAGATTTTTTTTCATTAAGTGGCAAAACTTTTTTAGTTACTGGAAGCGAAGGTTTAATTGGCTTGGATTT
ATGCAAAAGACTATTAGAGG

Product: CMP-N-acetylneuraminic acid synthetase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSKDFYAFIFARGGSKGITKKNLRKINGISLVRRSIDLALQLDNVLKIFLSTDSQEIANEVNSLDVEVIKRPYELAKDET
SEILAWKHAINVVEEKFGSFDKFVSIPPTSPLRSLEDVKNIMFLLNAKFDLTLGITKSKRNPWFNMVKKSEGNQVTKIFN
DKSFSRRQDAPLTFDLTTVAYAAHTSYVINSKNLLDGVIGGLEIPEERSLDIDTEIDLKMAEFFLNQ

Sequences:

>Translated_227_residues
MSKDFYAFIFARGGSKGITKKNLRKINGISLVRRSIDLALQLDNVLKIFLSTDSQEIANEVNSLDVEVIKRPYELAKDET
SEILAWKHAINVVEEKFGSFDKFVSIPPTSPLRSLEDVKNIMFLLNAKFDLTLGITKSKRNPWFNMVKKSEGNQVTKIFN
DKSFSRRQDAPLTFDLTTVAYAAHTSYVINSKNLLDGVIGGLEIPEERSLDIDTEIDLKMAEFFLNQ
>Mature_226_residues
SKDFYAFIFARGGSKGITKKNLRKINGISLVRRSIDLALQLDNVLKIFLSTDSQEIANEVNSLDVEVIKRPYELAKDETS
EILAWKHAINVVEEKFGSFDKFVSIPPTSPLRSLEDVKNIMFLLNAKFDLTLGITKSKRNPWFNMVKKSEGNQVTKIFND
KSFSRRQDAPLTFDLTTVAYAAHTSYVINSKNLLDGVIGGLEIPEERSLDIDTEIDLKMAEFFLNQ

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=219, Percent_Identity=27.8538812785388, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: 2.7.7.43

Molecular weight: Translated: 25730; Mature: 25599

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDFYAFIFARGGSKGITKKNLRKINGISLVRRSIDLALQLDNVLKIFLSTDSQEIANE
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHH
VNSLDVEVIKRPYELAKDETSEILAWKHAINVVEEKFGSFDKFVSIPPTSPLRSLEDVKN
HHHCCHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHH
IMFLLNAKFDLTLGITKSKRNPWFNMVKKSEGNQVTKIFNDKSFSRRQDAPLTFDLTTVA
HHHHHCCCEEEEEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
YAAHTSYVINSKNLLDGVIGGLEIPEERSLDIDTEIDLKMAEFFLNQ
HHHHHEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SKDFYAFIFARGGSKGITKKNLRKINGISLVRRSIDLALQLDNVLKIFLSTDSQEIANE
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHH
VNSLDVEVIKRPYELAKDETSEILAWKHAINVVEEKFGSFDKFVSIPPTSPLRSLEDVKN
HHHCCHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHH
IMFLLNAKFDLTLGITKSKRNPWFNMVKKSEGNQVTKIFNDKSFSRRQDAPLTFDLTTVA
HHHHHCCCEEEEEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHH
YAAHTSYVINSKNLLDGVIGGLEIPEERSLDIDTEIDLKMAEFFLNQ
HHHHHEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]