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The map label for this gene is ptmA [H]

Identifier: 126696750

GI number: 126696750

Start: 1179126

End: 1179884

Strand: Reverse

Name: ptmA [H]

Synonym: P9301_14121

Alternate gene names: 126696750

Gene position: 1179884-1179126 (Counterclockwise)

Preceding gene: 126696751

Following gene: 126696749

Centisome position: 71.86

GC content: 30.43

Gene sequence:

>759_bases
ATGGAAGATTTTTTTTCATTAAGTGGCAAAACTTTTTTAGTTACTGGAAGCGAAGGTTTAATTGGCTTGGATTTATGCAA
AAGACTATTAGAGGCTGGTGCTGATGTAATTTCTTGTGATTTAAAAAGCCCAACAAATACTTCTAATTCAGATAAAAATA
GTTTTTTTGAATGTGATTTAACGACGAATAAAGGTTTAAGAGAGTTCAAGGATTTTATCAGAAATTGTGGGGTAAAAATT
AATGGTTTCGTGCACTGTGCTTATCCTAGACCAGAAAGTTGGGGTAAATTATTTGATGAGATATCTCTTGATGAAGTCAG
TTTGCATTTAAATATGCAATTAAGCTCTTCTATAATTTTATCAAGAATAATTTGCAACTATTTAAAAATAAATGGAGGGG
GCAGTCTTGTAAATATTGCATCAATACAAGGTATAGCTGCACCTAAGTTTCATCACTATCGTGGAACAAGCATGAGTTCT
CCCATAGAATATTCTTGTGTTAAATCTTCAATAATAATAATGACTAAATGGCTTGCTAAATATTTTAAAAATTCTAATTT
AAATATTAACTGTGTTAGCCCAGGAGGAGTATTGGATAAACAGTTAGAAATTTTTCAGAATAACTATAAATCAGATTGCA
ATAATATTGGCCTACTTAAACCAAAAAATGTTTCATATCCTATTTTGTTTCTTCTCTCAGATCAAGCAAAAGGTATATCT
GGTCAGAATTTAATAGTTGATGATGGGTGGTCTTTATGA

Upstream 100 bases:

>100_bases
AGTTATTGGAGGCTTAGAAATACCAGAAGAAAGATCTTTAGATATTGATACGGAAATTGATTTAAAAATGGCCGAATTCT
TTTTAAATCAGTGATTTAAT

Downstream 100 bases:

>100_bases
ATAAAAATAGAAAAGTATTAGTTACTGGTGCAGATGGCTTTATAGGATCTCATTTAACGGAAATGCTTGTTAGAAAAGGG
TACGAAGTTAATGCTTTCTG

Product: flagellin modification protein A

Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MEDFFSLSGKTFLVTGSEGLIGLDLCKRLLEAGADVISCDLKSPTNTSNSDKNSFFECDLTTNKGLREFKDFIRNCGVKI
NGFVHCAYPRPESWGKLFDEISLDEVSLHLNMQLSSSIILSRIICNYLKINGGGSLVNIASIQGIAAPKFHHYRGTSMSS
PIEYSCVKSSIIIMTKWLAKYFKNSNLNINCVSPGGVLDKQLEIFQNNYKSDCNNIGLLKPKNVSYPILFLLSDQAKGIS
GQNLIVDDGWSL

Sequences:

>Translated_252_residues
MEDFFSLSGKTFLVTGSEGLIGLDLCKRLLEAGADVISCDLKSPTNTSNSDKNSFFECDLTTNKGLREFKDFIRNCGVKI
NGFVHCAYPRPESWGKLFDEISLDEVSLHLNMQLSSSIILSRIICNYLKINGGGSLVNIASIQGIAAPKFHHYRGTSMSS
PIEYSCVKSSIIIMTKWLAKYFKNSNLNINCVSPGGVLDKQLEIFQNNYKSDCNNIGLLKPKNVSYPILFLLSDQAKGIS
GQNLIVDDGWSL
>Mature_252_residues
MEDFFSLSGKTFLVTGSEGLIGLDLCKRLLEAGADVISCDLKSPTNTSNSDKNSFFECDLTTNKGLREFKDFIRNCGVKI
NGFVHCAYPRPESWGKLFDEISLDEVSLHLNMQLSSSIILSRIICNYLKINGGGSLVNIASIQGIAAPKFHHYRGTSMSS
PIEYSCVKSSIIIMTKWLAKYFKNSNLNINCVSPGGVLDKQLEIFQNNYKSDCNNIGLLKPKNVSYPILFLLSDQAKGIS
GQNLIVDDGWSL

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=25.390625, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125 [C]

Molecular weight: Translated: 27842; Mature: 27842

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFFSLSGKTFLVTGSEGLIGLDLCKRLLEAGADVISCDLKSPTNTSNSDKNSFFECDL
CCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEE
TTNKGLREFKDFIRNCGVKINGFVHCAYPRPESWGKLFDEISLDEVSLHLNMQLSSSIIL
CCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHCCCEEEEEEEEEEHHHHHHH
SRIICNYLKINGGGSLVNIASIQGIAAPKFHHYRGTSMSSPIEYSCVKSSIIIMTKWLAK
HHHHHHHEEECCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YFKNSNLNINCVSPGGVLDKQLEIFQNNYKSDCNNIGLLKPKNVSYPILFLLSDQAKGIS
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
GQNLIVDDGWSL
CCEEEEECCCCC
>Mature Secondary Structure
MEDFFSLSGKTFLVTGSEGLIGLDLCKRLLEAGADVISCDLKSPTNTSNSDKNSFFECDL
CCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEE
TTNKGLREFKDFIRNCGVKINGFVHCAYPRPESWGKLFDEISLDEVSLHLNMQLSSSIIL
CCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHCCCEEEEEEEEEEHHHHHHH
SRIICNYLKINGGGSLVNIASIQGIAAPKFHHYRGTSMSSPIEYSCVKSSIIIMTKWLAK
HHHHHHHEEECCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YFKNSNLNINCVSPGGVLDKQLEIFQNNYKSDCNNIGLLKPKNVSYPILFLLSDQAKGIS
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCC
GQNLIVDDGWSL
CCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 15.4 {2-deoxygluconate}} [C]

Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]

Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]