Click here to switch to the map view.

The map label for this gene is yadA [H]

Identifier: 126447035

GI number: 126447035

Start: 932441

End: 934891

Strand: Direct

Name: yadA [H]

Synonym: BMA10247_A0985

Alternate gene names: 126447035

Gene position: 932441-934891 (Clockwise)

Preceding gene: 126445762

Following gene: 126447564

Centisome position: 39.63

GC content: 70.5

Gene sequence:

>2451_bases
TTGATTGCGGTTTCTGAATTTTCCCGGTCGAATGGCAAGTGTTCGACGACGCAGGTCGTCACGGCGGCGCCGGGCGTTGC
CGGTCGTACCGCGGCTTCTGGCCGATCGCGCCCGTCGTGGACGAAGCTCGGGCTGATGTCGCTGGCGGTGAGCGCGGCGA
TGGGCTGCATGGCGACCGACGCCGCGGCGCAGGTCAGCTATGCGGCGGGCGAGAACGCCTATGCCGGCCCCGGCGGCAAT
ACCGGCCCGTGGGCGTTCTACAACCCGGCCTTCAGCGCGGGCACGCTGCTGTACGGCACCGCGGTCGGCAACTACGCCTA
TGCGAACGGCGAGGGCAGCTCGGCCTACGGCGATCACGCGACGGTGAAGGGGCGCATCGGCTCCGCGTTCGGCGCGTATT
CGGAAGCGGCGGGCGACGGCAGCACTGCAATCGGCGCCAGCGCGCGGGCGCTGCCGGACTTCAGCATCGCGATCGGCACG
AACGCGCAGGCGCTGAAGGACACGGGCCAATCGATTCCCGGCCGCGAAGACATCGGCACGATCGCGATCGGCGCGGGCGC
GCTCGCGCAGGGCGACAACAGCGATCCGCTGCACGTGTCCGCGCCGAACGCGTTCGGCGGCTATTCGAGCGCGACGGCAA
GCGGCGCGGTGGCGCTGGGCGAAGGCGCCGCATCGTCCGGCTATTACGCGAACGCGCTCGGCTCGTATTCGAAGGCGTCG
GGTGCGGGTGCGGTCGCGGTGGGCGGCGGCGCGCAAGCGAGCGCGCAAGGCGCGGTGGCGATCGGCGGCGCGACGAGCGT
CGACAACGCAACCGCGCTGTCCGGCTACGCGAGCGCAAGCGGCGTCAACGCGATCGCGATCGGTTCCGGCGCGCAGGCGA
CGGGCGCCCGGTCGATCAGCATCGGCACGGGCAACGTCGTGTCGGGGGCGAGCTCGGGCGCCTTCGGCGATCCGTCGACG
GTCACGGGCACGGGCTCGTATTCGTTCGGCAACAACAACACGATCAATTCGAACAACGCGTTCGTGCTCGGCAACAACGT
GACGATCGGCCCAGGGTTCGACGGCTCGGTCGCGCTCGGTAGCGGCACGACGCTCGCCGCGGCGAACCCCACCGGCAGCG
CGACGATCACGACGAGCTCGGGCGGCCAGTTGACGCTGTCCGGCTTCGCCGGCGCGAATCCGACGAGCGTCGTCAGCGTC
GGCGCGCCCGGCGCCGAGCGCCAGATCACGAACGTCGCGGCGGGGCGCATCACGCCGACGTCGACGGATGCCGTCAACGG
CAGCCAGCTGTATGCGGTCGCGAGCACGATCGACAATGCGGTGAACGGCGGCGGGATCAAGTACTTCCACGCGAATTCGA
CCCTGGCCGATTCGACGGCGGCGGGCACGGACAGCGTCGCGGTCGGGCCGGCCGCGCTCGCCTACGGCAACGATTCGATC
GCCGAAGGCACGAACGCGACGGCGGGCGTGAGCGGCAATCCGGCGGTGGCGGGCGATGTCGCGCTCGGCAGCGGCGCGCA
GGCGACGGGAGGCCGCTCGCTCGCGCTCGGCGCGAACGCGTCGGTCAACACGGCGGGCGGCGTGGCGCTCGGCGCCGGCT
CGGTCGCGAACCGCGCGGCCGGCACGTACACCGATCCGATCACGGGCAGCAGCTTCACGACCGCATTCGGCGCGGTGTCG
GTCGGCCTCGAGGGTTCGCTGCGCCAGATCACCAACGTCGCGGCGGGCACGCAGGCAACGGATGCGGTAAACGTCGGTCA
GTTGCAAGGCGCGATTGCGCAGTTGAATCAGACGATCCAGAACATCACGAACGGCTCCAACTCGGGCAACACCGGCAATA
ACGGCAACAACACCGGGCAGACCGTGTCGGGCCAGTGGATCACGGGCAACCCGTCGACCTATACGCCGCCCGTGGCGAGC
GGCATCGGCTCGACCGCCGCGGGCAGCGGCAGCGTGGCGTCCGGCGCGAACAGCGTCGCGATCGGCGACGGCGCGTCGGC
CTCCGGCAACAACTCGGTGGCGCTCGGCGCCCATTCGGTCGCGAGCGCGCCGAACACGGTGTCGGTCGGCTCGGTCGGCA
ACGAGCGGACGATCTCGAACGTCGCGCCGGGCGTGAACGGCACCGATGCGGTGAACGTGAACCAGTTGAACAGCGGTATC
GGCAATGCGGTCGGCCAGGCGAATCAGTACACGGATCAGAAGGTCGACCATCTGCGGCGCGAGATGAACGGCGGCGTGGC
TGCGGCGATGGCCGTGGCGGGCTTGCCGCAGCCGACCGCGCCCGGCAAGAGCATGGTCGCGATCGCCGGCTCGACGTGGC
AGGGGCAGCAGGGCTTCGCGCTTGGCGTATCGACGATTTCCGAGAACGGCAAGTGGCTGTACAAGGGCTCGCTCACGACC
AGCACGCGCGGCGGCACGGGCGCGGTGCTCGGGGCCGGTTATCAGTGGTGA

Upstream 100 bases:

>100_bases
CTCGAAAATGACCCTGCTGACGGCCCGTGCGAATTGAATTCACAGGGGATATCGAGTGAACAAAATCTACAATGTGGTTT
GGAGTCGGGTGCGAGGCCAA

Downstream 100 bases:

>100_bases
CGCGAGTCGCAACGGCGGCCGGCGCGGCGCCGGCCGTGGAGACGATAAGGAATCCAATATGAAAATGAACAGGATGTCGA
AATATGCGGCCGCCGCCGGG

Product: haemagluttinin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 816

Protein sequence:

>816_residues
MIAVSEFSRSNGKCSTTQVVTAAPGVAGRTAASGRSRPSWTKLGLMSLAVSAAMGCMATDAAAQVSYAAGENAYAGPGGN
TGPWAFYNPAFSAGTLLYGTAVGNYAYANGEGSSAYGDHATVKGRIGSAFGAYSEAAGDGSTAIGASARALPDFSIAIGT
NAQALKDTGQSIPGREDIGTIAIGAGALAQGDNSDPLHVSAPNAFGGYSSATASGAVALGEGAASSGYYANALGSYSKAS
GAGAVAVGGGAQASAQGAVAIGGATSVDNATALSGYASASGVNAIAIGSGAQATGARSISIGTGNVVSGASSGAFGDPST
VTGTGSYSFGNNNTINSNNAFVLGNNVTIGPGFDGSVALGSGTTLAAANPTGSATITTSSGGQLTLSGFAGANPTSVVSV
GAPGAERQITNVAAGRITPTSTDAVNGSQLYAVASTIDNAVNGGGIKYFHANSTLADSTAAGTDSVAVGPAALAYGNDSI
AEGTNATAGVSGNPAVAGDVALGSGAQATGGRSLALGANASVNTAGGVALGAGSVANRAAGTYTDPITGSSFTTAFGAVS
VGLEGSLRQITNVAAGTQATDAVNVGQLQGAIAQLNQTIQNITNGSNSGNTGNNGNNTGQTVSGQWITGNPSTYTPPVAS
GIGSTAAGSGSVASGANSVAIGDGASASGNNSVALGAHSVASAPNTVSVGSVGNERTISNVAPGVNGTDAVNVNQLNSGI
GNAVGQANQYTDQKVDHLRREMNGGVAAAMAVAGLPQPTAPGKSMVAIAGSTWQGQQGFALGVSTISENGKWLYKGSLTT
STRGGTGAVLGAGYQW

Sequences:

>Translated_816_residues
MIAVSEFSRSNGKCSTTQVVTAAPGVAGRTAASGRSRPSWTKLGLMSLAVSAAMGCMATDAAAQVSYAAGENAYAGPGGN
TGPWAFYNPAFSAGTLLYGTAVGNYAYANGEGSSAYGDHATVKGRIGSAFGAYSEAAGDGSTAIGASARALPDFSIAIGT
NAQALKDTGQSIPGREDIGTIAIGAGALAQGDNSDPLHVSAPNAFGGYSSATASGAVALGEGAASSGYYANALGSYSKAS
GAGAVAVGGGAQASAQGAVAIGGATSVDNATALSGYASASGVNAIAIGSGAQATGARSISIGTGNVVSGASSGAFGDPST
VTGTGSYSFGNNNTINSNNAFVLGNNVTIGPGFDGSVALGSGTTLAAANPTGSATITTSSGGQLTLSGFAGANPTSVVSV
GAPGAERQITNVAAGRITPTSTDAVNGSQLYAVASTIDNAVNGGGIKYFHANSTLADSTAAGTDSVAVGPAALAYGNDSI
AEGTNATAGVSGNPAVAGDVALGSGAQATGGRSLALGANASVNTAGGVALGAGSVANRAAGTYTDPITGSSFTTAFGAVS
VGLEGSLRQITNVAAGTQATDAVNVGQLQGAIAQLNQTIQNITNGSNSGNTGNNGNNTGQTVSGQWITGNPSTYTPPVAS
GIGSTAAGSGSVASGANSVAIGDGASASGNNSVALGAHSVASAPNTVSVGSVGNERTISNVAPGVNGTDAVNVNQLNSGI
GNAVGQANQYTDQKVDHLRREMNGGVAAAMAVAGLPQPTAPGKSMVAIAGSTWQGQQGFALGVSTISENGKWLYKGSLTT
STRGGTGAVLGAGYQW
>Mature_816_residues
MIAVSEFSRSNGKCSTTQVVTAAPGVAGRTAASGRSRPSWTKLGLMSLAVSAAMGCMATDAAAQVSYAAGENAYAGPGGN
TGPWAFYNPAFSAGTLLYGTAVGNYAYANGEGSSAYGDHATVKGRIGSAFGAYSEAAGDGSTAIGASARALPDFSIAIGT
NAQALKDTGQSIPGREDIGTIAIGAGALAQGDNSDPLHVSAPNAFGGYSSATASGAVALGEGAASSGYYANALGSYSKAS
GAGAVAVGGGAQASAQGAVAIGGATSVDNATALSGYASASGVNAIAIGSGAQATGARSISIGTGNVVSGASSGAFGDPST
VTGTGSYSFGNNNTINSNNAFVLGNNVTIGPGFDGSVALGSGTTLAAANPTGSATITTSSGGQLTLSGFAGANPTSVVSV
GAPGAERQITNVAAGRITPTSTDAVNGSQLYAVASTIDNAVNGGGIKYFHANSTLADSTAAGTDSVAVGPAALAYGNDSI
AEGTNATAGVSGNPAVAGDVALGSGAQATGGRSLALGANASVNTAGGVALGAGSVANRAAGTYTDPITGSSFTTAFGAVS
VGLEGSLRQITNVAAGTQATDAVNVGQLQGAIAQLNQTIQNITNGSNSGNTGNNGNNTGQTVSGQWITGNPSTYTPPVAS
GIGSTAAGSGSVASGANSVAIGDGASASGNNSVALGAHSVASAPNTVSVGSVGNERTISNVAPGVNGTDAVNVNQLNSGI
GNAVGQANQYTDQKVDHLRREMNGGVAAAMAVAGLPQPTAPGKSMVAIAGSTWQGQQGFALGVSTISENGKWLYKGSLTT
STRGGTGAVLGAGYQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 77760; Mature: 77760

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVSEFSRSNGKCSTTQVVTAAPGVAGRTAASGRSRPSWTKLGLMSLAVSAAMGCMATD
CEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
AAAQVSYAAGENAYAGPGGNTGPWAFYNPAFSAGTLLYGTAVGNYAYANGEGSSAYGDHA
HHHHEEECCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEECCCCCCCCCCCC
TVKGRIGSAFGAYSEAAGDGSTAIGASARALPDFSIAIGTNAQALKDTGQSIPGREDIGT
EEECCCCCHHCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCE
IAIGAGALAQGDNSDPLHVSAPNAFGGYSSATASGAVALGEGAASSGYYANALGSYSKAS
EEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHCCCCCCC
GAGAVAVGGGAQASAQGAVAIGGATSVDNATALSGYASASGVNAIAIGSGAQATGARSIS
CCCEEEECCCCCCCCCCEEEECCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCEEEE
IGTGNVVSGASSGAFGDPSTVTGTGSYSFGNNNTINSNNAFVLGNNVTIGPGFDGSVALG
ECCCCEECCCCCCCCCCCCEEECCCCEECCCCCEECCCCCEEECCCEEECCCCCCCEEEC
SGTTLAAANPTGSATITTSSGGQLTLSGFAGANPTSVVSVGAPGAERQITNVAAGRITPT
CCCEEEECCCCCCEEEEECCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCC
STDAVNGSQLYAVASTIDNAVNGGGIKYFHANSTLADSTAAGTDSVAVGPAALAYGNDSI
CCCCCCCCEEEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEECCEEEECCCCCC
AEGTNATAGVSGNPAVAGDVALGSGAQATGGRSLALGANASVNTAGGVALGAGSVANRAA
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEECCCCHHHCCC
GTYTDPITGSSFTTAFGAVSVGLEGSLRQITNVAAGTQATDAVNVGQLQGAIAQLNQTIQ
CCCCCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NITNGSNSGNTGNNGNNTGQTVSGQWITGNPSTYTPPVASGIGSTAAGSGSVASGANSVA
HHHCCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEE
IGDGASASGNNSVALGAHSVASAPNTVSVGSVGNERTISNVAPGVNGTDAVNVNQLNSGI
ECCCCCCCCCCEEEEECHHHCCCCCEEEECCCCCCCCHHHHCCCCCCCCEEEHHHHHCHH
GNAVGQANQYTDQKVDHLRREMNGGVAAAMAVAGLPQPTAPGKSMVAIAGSTWQGQQGFA
HHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEE
LGVSTISENGKWLYKGSLTTSTRGGTGAVLGAGYQW
EEEEECCCCCCEEEECCCEECCCCCCCEEECCCCCC
>Mature Secondary Structure
MIAVSEFSRSNGKCSTTQVVTAAPGVAGRTAASGRSRPSWTKLGLMSLAVSAAMGCMATD
CEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
AAAQVSYAAGENAYAGPGGNTGPWAFYNPAFSAGTLLYGTAVGNYAYANGEGSSAYGDHA
HHHHEEECCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCEEEECCCCCCCCCCCC
TVKGRIGSAFGAYSEAAGDGSTAIGASARALPDFSIAIGTNAQALKDTGQSIPGREDIGT
EEECCCCCHHCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCE
IAIGAGALAQGDNSDPLHVSAPNAFGGYSSATASGAVALGEGAASSGYYANALGSYSKAS
EEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHCCCCCCC
GAGAVAVGGGAQASAQGAVAIGGATSVDNATALSGYASASGVNAIAIGSGAQATGARSIS
CCCEEEECCCCCCCCCCEEEECCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCEEEE
IGTGNVVSGASSGAFGDPSTVTGTGSYSFGNNNTINSNNAFVLGNNVTIGPGFDGSVALG
ECCCCEECCCCCCCCCCCCEEECCCCEECCCCCEECCCCCEEECCCEEECCCCCCCEEEC
SGTTLAAANPTGSATITTSSGGQLTLSGFAGANPTSVVSVGAPGAERQITNVAAGRITPT
CCCEEEECCCCCCEEEEECCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCC
STDAVNGSQLYAVASTIDNAVNGGGIKYFHANSTLADSTAAGTDSVAVGPAALAYGNDSI
CCCCCCCCEEEEEHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEECCEEEECCCCCC
AEGTNATAGVSGNPAVAGDVALGSGAQATGGRSLALGANASVNTAGGVALGAGSVANRAA
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEECCCCHHHCCC
GTYTDPITGSSFTTAFGAVSVGLEGSLRQITNVAAGTQATDAVNVGQLQGAIAQLNQTIQ
CCCCCCCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NITNGSNSGNTGNNGNNTGQTVSGQWITGNPSTYTPPVASGIGSTAAGSGSVASGANSVA
HHHCCCCCCCCCCCCCCCCCEEECEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCEEE
IGDGASASGNNSVALGAHSVASAPNTVSVGSVGNERTISNVAPGVNGTDAVNVNQLNSGI
ECCCCCCCCCCEEEEECHHHCCCCCEEEECCCCCCCCHHHHCCCCCCCCEEEHHHHHCHH
GNAVGQANQYTDQKVDHLRREMNGGVAAAMAVAGLPQPTAPGKSMVAIAGSTWQGQQGFA
HHHHCCCCHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEE
LGVSTISENGKWLYKGSLTTSTRGGTGAVLGAGYQW
EEEEECCCCCCEEEECCCEECCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14527656; 2592347 [H]