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The map label for this gene is znuB [H]

Identifier: 126207923

GI number: 126207923

Start: 495860

End: 496645

Strand: Direct

Name: znuB [H]

Synonym: APL_0439

Alternate gene names: 126207923

Gene position: 495860-496645 (Clockwise)

Preceding gene: 126207922

Following gene: 126207924

Centisome position: 21.8

GC content: 43.0

Gene sequence:

>786_bases
ATGTTTGAGATTCTATTCCCCGCTTGGTTAGCCGGTTTGTTACTGGCATTTATAACGGCACCGCTCGGTGCTTTTGTCGT
ATGGCGAAAAATGGCATATTTCGGCGATACGCTTTCTCATTCCGCCTTACTTGGCGTTGCGCTCGGTATTTTTTTACAGA
TTGATCCTTATATAGCGGTGATTGTGATGACGCTGATTTTGGCAATGCTACTTGTATGGCTGGAACATAAAACCGCTTAT
TCCTTGGATACGGTATTGGGAATTATCGCACACTGTAGTTTATCGTTAGGGGTGATTACCATTAGTTTGTTGGATAATGT
CCGTGTTGATCTGATGTCGTATCTATTCGGCGATTTGCTGGCAATTGACTTTAACGACGTAGTATTTATCGGGGCCGGTA
CTTTATTTATCGCCGGTGTATTAGGCTATTTTTGGAAAAAACTACTTTCCATTACGATTAGCCCCGAATTAGCGCAAATC
GAAGGATTGAATGTGGTGCGCTTACGTCTGTTGTTGATGTTGCTTACCGCATTAACCATCGCATTAAGTATGAAATTTGT
CGGTGCATTGATTATCACTTCCTTATTAATTATTCCTTCGGCAATTGCTCGTCGTTTTGCCAAAACGCCGGAAGCGATGG
TCGGATATGCGATTATATTCAGTATTTTTTCCATTACGGGAGGATTACTGTTCTCCGCTTGGAAAGATACGCCGGCCGGG
CCTTCCGTGGTCGTTTGTGCCGGCGCAATCTTCTTACTTTCTCTCTTTAGAAAAGAGAAAGTATAG

Upstream 100 bases:

>100_bases
AACAACGTTACAAGCGGTAATATTTTAAACTTTTTTTGCAAAATTTTAGAGAAATCCGACCGCTTGTACTGCATTGAAAA
ATAAAAAGATAGAGAGAGAA

Downstream 100 bases:

>100_bases
CGGTTAGTGAAGAAAATTAATTCATATAGCAAAATAAATATAAATAATGACTACAAGCTATAAAATTTTTGATCTGCTTC
TATTGAATTATTTTTAGGAT

Product: high-affinity zinc uptake system membrane protein ZnuB

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFEILFPAWLAGLLLAFITAPLGAFVVWRKMAYFGDTLSHSALLGVALGIFLQIDPYIAVIVMTLILAMLLVWLEHKTAY
SLDTVLGIIAHCSLSLGVITISLLDNVRVDLMSYLFGDLLAIDFNDVVFIGAGTLFIAGVLGYFWKKLLSITISPELAQI
EGLNVVRLRLLLMLLTALTIALSMKFVGALIITSLLIIPSAIARRFAKTPEAMVGYAIIFSIFSITGGLLFSAWKDTPAG
PSVVVCAGAIFLLSLFRKEKV

Sequences:

>Translated_261_residues
MFEILFPAWLAGLLLAFITAPLGAFVVWRKMAYFGDTLSHSALLGVALGIFLQIDPYIAVIVMTLILAMLLVWLEHKTAY
SLDTVLGIIAHCSLSLGVITISLLDNVRVDLMSYLFGDLLAIDFNDVVFIGAGTLFIAGVLGYFWKKLLSITISPELAQI
EGLNVVRLRLLLMLLTALTIALSMKFVGALIITSLLIIPSAIARRFAKTPEAMVGYAIIFSIFSITGGLLFSAWKDTPAG
PSVVVCAGAIFLLSLFRKEKV
>Mature_261_residues
MFEILFPAWLAGLLLAFITAPLGAFVVWRKMAYFGDTLSHSALLGVALGIFLQIDPYIAVIVMTLILAMLLVWLEHKTAY
SLDTVLGIIAHCSLSLGVITISLLDNVRVDLMSYLFGDLLAIDFNDVVFIGAGTLFIAGVLGYFWKKLLSITISPELAQI
EGLNVVRLRLLLMLLTALTIALSMKFVGALIITSLLIIPSAIARRFAKTPEAMVGYAIIFSIFSITGGLLFSAWKDTPAG
PSVVVCAGAIFLLSLFRKEKV

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=259, Percent_Identity=57.9150579150579, Blast_Score=313, Evalue=7e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28330; Mature: 28330

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]