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The map label for this gene is mreD [H]

Identifier: 126207921

GI number: 126207921

Start: 493938

End: 494426

Strand: Direct

Name: mreD [H]

Synonym: APL_0437

Alternate gene names: 126207921

Gene position: 493938-494426 (Clockwise)

Preceding gene: 126207920

Following gene: 126207922

Centisome position: 21.72

GC content: 37.63

Gene sequence:

>489_bases
ATGCGTACGAATCCATTGTTTCAGATTTTAGTATTACTTTTAATTTTTATTATTGCTTTTGTATTGGAAATTATGCCATG
GCCGGTCGGGTTGCAAGGTTTACGCCCAAGTTGGCTCGTACTGGTACTTATCTATTGGGCGTTGGCCTTACCTAATAAAA
TTAGTGTCGGAACGGCATTTGTTGCCGGTATCGTTTGGGATCTGATTTTAGGTTCTATTTTAGGCATTCATGCATTAGTA
TTATCTATTGCGATTTATTTTGTGGCGAAACATCATCTTATTTTACGTAACTTATCGCTTTGGTTACAGGCGATTTTGGT
GATGCTTTATGTGATACTTATCCGTTTTATGATCTTCTTTGTTGAATTGGTATTACATAGCGCCGAATTTAATACTCAAG
AAATTTTAGGTGCGATAATCAGTGGGATTTTATGGCCATGGATCTTCTTACTGATGCGCCAAATTCGCCGTCAGCTCAGA
TTACGTTAG

Upstream 100 bases:

>100_bases
AGGAAGAATTATTAGACGGTTCGGATGAGAGTATCAATCCGGAAAGCCAGTTTGAATTGGATAACGAAGAAAATAATCAT
ACAGAGCAAGGAGCCGAGTA

Downstream 100 bases:

>100_bases
TGAGGTATGGCTATGAGTAGTTTGTCCTTTGATTTTTCAGAAGATTTTAGACCGCTGCCCGCCAGAATGCGTCCACGCAC
ACTGGCGGAGTATATCGGGC

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRTNPLFQILVLLLIFIIAFVLEIMPWPVGLQGLRPSWLVLVLIYWALALPNKISVGTAFVAGIVWDLILGSILGIHALV
LSIAIYFVAKHHLILRNLSLWLQAILVMLYVILIRFMIFFVELVLHSAEFNTQEILGAIISGILWPWIFLLMRQIRRQLR
LR

Sequences:

>Translated_162_residues
MRTNPLFQILVLLLIFIIAFVLEIMPWPVGLQGLRPSWLVLVLIYWALALPNKISVGTAFVAGIVWDLILGSILGIHALV
LSIAIYFVAKHHLILRNLSLWLQAILVMLYVILIRFMIFFVELVLHSAEFNTQEILGAIISGILWPWIFLLMRQIRRQLR
LR
>Mature_162_residues
MRTNPLFQILVLLLIFIIAFVLEIMPWPVGLQGLRPSWLVLVLIYWALALPNKISVGTAFVAGIVWDLILGSILGIHALV
LSIAIYFVAKHHLILRNLSLWLQAILVMLYVILIRFMIFFVELVLHSAEFNTQEILGAIISGILWPWIFLLMRQIRRQLR
LR

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=152, Percent_Identity=44.7368421052632, Blast_Score=132, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18691; Mature: 18691

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTNPLFQILVLLLIFIIAFVLEIMPWPVGLQGLRPSWLVLVLIYWALALPNKISVGTAF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VAGIVWDLILGSILGIHALVLSIAIYFVAKHHLILRNLSLWLQAILVMLYVILIRFMIFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELVLHSAEFNTQEILGAIISGILWPWIFLLMRQIRRQLRLR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTNPLFQILVLLLIFIIAFVLEIMPWPVGLQGLRPSWLVLVLIYWALALPNKISVGTAF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VAGIVWDLILGSILGIHALVLSIAIYFVAKHHLILRNLSLWLQAILVMLYVILIRFMIFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELVLHSAEFNTQEILGAIISGILWPWIFLLMRQIRRQLRLR
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]