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The map label for this gene is mreC [H]

Identifier: 126207920

GI number: 126207920

Start: 492889

End: 493938

Strand: Direct

Name: mreC [H]

Synonym: APL_0436

Alternate gene names: 126207920

Gene position: 492889-493938 (Clockwise)

Preceding gene: 126207919

Following gene: 126207921

Centisome position: 21.67

GC content: 41.33

Gene sequence:

>1050_bases
ATGAAACCGATTTTTGCTAAAGCCCCGTCATTAGGCGTACGTCTATTTCTTGCTATCGTCATTTCTATCGTGCTTATTGC
TTTTGACGGTAGAAGCAGCGCGATCATTCAATTCCGTAATATGCTGGAAACTGCAATAAGCGGTCTATATTATTTTGCAA
ATACGCCGCGTTCCGTATTAGATGGAGTGAGTAACAACTTTATTGATAACAATAAGTTGCAGATGGAAAATCATGTTTTA
AAAGAACAGTTGCGAGAAAAAAATGCGGATCTACTTTTATTAGATCAACTTAAAGTAGAAAACCAGCGATTACGTTTATT
ACTGAGTTCGCCGTTACGCCAAGACGAATATAAAAAGATCGGCGAAGTCTTAACCGCCGAGATGGACGCTTATCGCCAAC
AAGTGATTATTAACCGAGGAAAAAGTGACGGTGCCTTTGTCGGTCAGCCGATTATTGATGAAAAAGGTGTGGTAGGTCAG
GTTATTTCCGTTGGTGAGAAAAGTAGTCGAGTATTATTAATTACGGATGTGACTCACGCCGTACCGGTGCAAGTATTGCG
TAATGATGTTCGCGGTATTGCGAACGGTACGGGACATAACGACGAGCTTTTTATTGATAATTTACCTCGTTCGGTTGATG
TAATCAAAGGTGATGTGTTAGTTACCTCAGGTTTAGGCGGCAGATTCCCCGAAGGCTATCCGGTTGCGATTGTGGAAGCG
GTAACTAATGATACGCAAAGCCAATTTGCTCGTATTGTCGCTCGTCCTCTCGCATCTTTTGATCGCTTAAGATATTTACT
CTTATTATGGCCTACCGGCGAAGAATTACGTAAAGCGCAAAGTTTATCGCCGCAACAAGTACGTGATGTGGTGGAAGAAA
GACGTAACAGCTTAAATCCGTTAGAACGCTTAAAAGAGAAGAAAAAAGAAGAAGTGAAAGAGGAAAGCAAGGAAGAATTA
TTAGACGGTTCGGATGAGAGTATCAATCCGGAAAGCCAGTTTGAATTGGATAACGAAGAAAATAATCATACAGAGCAAGG
AGCCGAGTAA

Upstream 100 bases:

>100_bases
TATGAATATTTACGATGGATAATGGCATTCGAATGTCCATTATCCATTGTTTATTATCAATCTCCATCTCTCACTCATTT
ACTTCTCAAAATAGTGAACA

Downstream 100 bases:

>100_bases
TGCGTACGAATCCATTGTTTCAGATTTTAGTATTACTTTTAATTTTTATTATTGCTTTTGTATTGGAAATTATGCCATGG
CCGGTCGGGTTGCAAGGTTT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MKPIFAKAPSLGVRLFLAIVISIVLIAFDGRSSAIIQFRNMLETAISGLYYFANTPRSVLDGVSNNFIDNNKLQMENHVL
KEQLREKNADLLLLDQLKVENQRLRLLLSSPLRQDEYKKIGEVLTAEMDAYRQQVIINRGKSDGAFVGQPIIDEKGVVGQ
VISVGEKSSRVLLITDVTHAVPVQVLRNDVRGIANGTGHNDELFIDNLPRSVDVIKGDVLVTSGLGGRFPEGYPVAIVEA
VTNDTQSQFARIVARPLASFDRLRYLLLLWPTGEELRKAQSLSPQQVRDVVEERRNSLNPLERLKEKKKEEVKEESKEEL
LDGSDESINPESQFELDNEENNHTEQGAE

Sequences:

>Translated_349_residues
MKPIFAKAPSLGVRLFLAIVISIVLIAFDGRSSAIIQFRNMLETAISGLYYFANTPRSVLDGVSNNFIDNNKLQMENHVL
KEQLREKNADLLLLDQLKVENQRLRLLLSSPLRQDEYKKIGEVLTAEMDAYRQQVIINRGKSDGAFVGQPIIDEKGVVGQ
VISVGEKSSRVLLITDVTHAVPVQVLRNDVRGIANGTGHNDELFIDNLPRSVDVIKGDVLVTSGLGGRFPEGYPVAIVEA
VTNDTQSQFARIVARPLASFDRLRYLLLLWPTGEELRKAQSLSPQQVRDVVEERRNSLNPLERLKEKKKEEVKEESKEEL
LDGSDESINPESQFELDNEENNHTEQGAE
>Mature_349_residues
MKPIFAKAPSLGVRLFLAIVISIVLIAFDGRSSAIIQFRNMLETAISGLYYFANTPRSVLDGVSNNFIDNNKLQMENHVL
KEQLREKNADLLLLDQLKVENQRLRLLLSSPLRQDEYKKIGEVLTAEMDAYRQQVIINRGKSDGAFVGQPIIDEKGVVGQ
VISVGEKSSRVLLITDVTHAVPVQVLRNDVRGIANGTGHNDELFIDNLPRSVDVIKGDVLVTSGLGGRFPEGYPVAIVEA
VTNDTQSQFARIVARPLASFDRLRYLLLLWPTGEELRKAQSLSPQQVRDVVEERRNSLNPLERLKEKKKEEVKEESKEEL
LDGSDESINPESQFELDNEENNHTEQGAE

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=300, Percent_Identity=50, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 39111; Mature: 39111

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFAKAPSLGVRLFLAIVISIVLIAFDGRSSAIIQFRNMLETAISGLYYFANTPRSVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DGVSNNFIDNNKLQMENHVLKEQLREKNADLLLLDQLKVENQRLRLLLSSPLRQDEYKKI
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHH
GEVLTAEMDAYRQQVIINRGKSDGAFVGQPIIDEKGVVGQVISVGEKSSRVLLITDVTHA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCHHH
VPVQVLRNDVRGIANGTGHNDELFIDNLPRSVDVIKGDVLVTSGLGGRFPEGYPVAIVEA
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHEECCEEEECCCCCCCCCCCCEEEHHH
VTNDTQSQFARIVARPLASFDRLRYLLLLWPTGEELRKAQSLSPQQVRDVVEERRNSLNP
HHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCH
LERLKEKKKEEVKEESKEELLDGSDESINPESQFELDNEENNHTEQGAE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKPIFAKAPSLGVRLFLAIVISIVLIAFDGRSSAIIQFRNMLETAISGLYYFANTPRSVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DGVSNNFIDNNKLQMENHVLKEQLREKNADLLLLDQLKVENQRLRLLLSSPLRQDEYKKI
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHH
GEVLTAEMDAYRQQVIINRGKSDGAFVGQPIIDEKGVVGQVISVGEKSSRVLLITDVTHA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCHHH
VPVQVLRNDVRGIANGTGHNDELFIDNLPRSVDVIKGDVLVTSGLGGRFPEGYPVAIVEA
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHEECCEEEECCCCCCCCCCCCEEEHHH
VTNDTQSQFARIVARPLASFDRLRYLLLLWPTGEELRKAQSLSPQQVRDVVEERRNSLNP
HHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCCCH
LERLKEKKKEEVKEESKEELLDGSDESINPESQFELDNEENNHTEQGAE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]