Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 126207730

GI number: 126207730

Start: 259949

End: 260893

Strand: Direct

Name: argC [H]

Synonym: APL_0242

Alternate gene names: 126207730

Gene position: 259949-260893 (Clockwise)

Preceding gene: 126207729

Following gene: 126207731

Centisome position: 11.43

GC content: 45.4

Gene sequence:

>945_bases
ATGAGTAAATATAAAATTTTTGTGGACGGAGCAGTCGGTACGACCGGTTTACGTATTTTTGACCGTCTAGCCAGTGCGGA
AGATATAGAATTATTAAGCTTGCCGGAAGAATTACGTAAAGATCTTAATGCCAGAGTGGCAAAAGTCGCGGAAGCGGATT
TGACTTTCCTCTGTTTACCGGACGAAGCCTCTAAAGAATTAGTGGCTCATGCACCGGCGGATGCAAGAATTTGCGATACT
TCAACCGCTCATCGTGTTAATCCGAACTGGACCTATGGCTTTGCAGAATTTTCCGGGCAGTTTGAAAAAATTCAAAATGC
GAATCGGGTCGCCGTACCGGGTTGTCACGCCACAGGTTATATTGCTTTAGTTCGTCCTCTTATTGAAAAAGGTGCATTGA
GTGCCGATTATCCACTTTCTTGCCATTCGCTCACCGGCTATTCCGGCGGCGGTAAAGCGATGATCGCCGAATATCAAAAT
CCGGATCGCGAACAAAAATTTAGTGCGCCTCGTGTCTACGGATTGGCTCTCAAACATAAACATTTACCGGAAATGCAAGC
GCTTACCGGTTCAAATCATCCTCCTATTTTCACTCCGGTTGTTGCCGACTATTACAGCGGAATGTTGGTGACTGTACCGC
TCCCTGTTTCCGCTCTTTCACAAGCGGTCAATTCTGCCGAAAAAATTGCAAATTTATTCAGCGAATATTACCAAAACTCA
AAATTGATTACGGTTCATCCCGCTTGCTCGCTACCTGAAGACGGAATGTTGGCGGCGAATACATTTAGCGGCAAAGACAG
CCTTGAAATCTTTGTTTACGGCAACGAAACGCAGCTATTATTGTGTGCACGTTTTGATAATTTAGGCAAAGGGGCATCCG
GTGCGGCGGTACAATGTATGAATATTATGCTAGGTCGTGAAGAAACAGCCGGACTAGACGTGTAG

Upstream 100 bases:

>100_bases
AATTATTCACTTTATGTGAATTTTTATTCTGTTTTGTGTTTGATATTGTGTCTGAATAAGAGTAAGATGTCTAACGTTTT
AACAGCAATAAGGATTTATG

Downstream 100 bases:

>100_bases
TCAGCGTGAGATATTATTTGGGGTTTAGAATGTTACAAAACGAAGTTGAAAATTTTGCAAATCTGTTAGAACAAGCGACC
GTTTATCTTGCTCCGTATCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSKYKIFVDGAVGTTGLRIFDRLASAEDIELLSLPEELRKDLNARVAKVAEADLTFLCLPDEASKELVAHAPADARICDT
STAHRVNPNWTYGFAEFSGQFEKIQNANRVAVPGCHATGYIALVRPLIEKGALSADYPLSCHSLTGYSGGGKAMIAEYQN
PDREQKFSAPRVYGLALKHKHLPEMQALTGSNHPPIFTPVVADYYSGMLVTVPLPVSALSQAVNSAEKIANLFSEYYQNS
KLITVHPACSLPEDGMLAANTFSGKDSLEIFVYGNETQLLLCARFDNLGKGASGAAVQCMNIMLGREETAGLDV

Sequences:

>Translated_314_residues
MSKYKIFVDGAVGTTGLRIFDRLASAEDIELLSLPEELRKDLNARVAKVAEADLTFLCLPDEASKELVAHAPADARICDT
STAHRVNPNWTYGFAEFSGQFEKIQNANRVAVPGCHATGYIALVRPLIEKGALSADYPLSCHSLTGYSGGGKAMIAEYQN
PDREQKFSAPRVYGLALKHKHLPEMQALTGSNHPPIFTPVVADYYSGMLVTVPLPVSALSQAVNSAEKIANLFSEYYQNS
KLITVHPACSLPEDGMLAANTFSGKDSLEIFVYGNETQLLLCARFDNLGKGASGAAVQCMNIMLGREETAGLDV
>Mature_313_residues
SKYKIFVDGAVGTTGLRIFDRLASAEDIELLSLPEELRKDLNARVAKVAEADLTFLCLPDEASKELVAHAPADARICDTS
TAHRVNPNWTYGFAEFSGQFEKIQNANRVAVPGCHATGYIALVRPLIEKGALSADYPLSCHSLTGYSGGGKAMIAEYQNP
DREQKFSAPRVYGLALKHKHLPEMQALTGSNHPPIFTPVVADYYSGMLVTVPLPVSALSQAVNSAEKIANLFSEYYQNSK
LITVHPACSLPEDGMLAANTFSGKDSLEIFVYGNETQLLLCARFDNLGKGASGAAVQCMNIMLGREETAGLDV

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=280, Percent_Identity=28.9285714285714, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320913, Length=266, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 33920; Mature: 33789

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYKIFVDGAVGTTGLRIFDRLASAEDIELLSLPEELRKDLNARVAKVAEADLTFLCLP
CCCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECC
DEASKELVAHAPADARICDTSTAHRVNPNWTYGFAEFSGQFEKIQNANRVAVPGCHATGY
CHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEHHHHCCHHHHHCCCCEEECCCCCCCHH
IALVRPLIEKGALSADYPLSCHSLTGYSGGGKAMIAEYQNPDREQKFSAPRVYGLALKHK
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEECCCC
HLPEMQALTGSNHPPIFTPVVADYYSGMLVTVPLPVSALSQAVNSAEKIANLFSEYYQNS
CCCCHHHHCCCCCCCEEHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
KLITVHPACSLPEDGMLAANTFSGKDSLEIFVYGNETQLLLCARFDNLGKGASGAAVQCM
EEEEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHH
NIMLGREETAGLDV
HHHHCCCCCCCCCC
>Mature Secondary Structure 
SKYKIFVDGAVGTTGLRIFDRLASAEDIELLSLPEELRKDLNARVAKVAEADLTFLCLP
CCEEEEEECCCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECC
DEASKELVAHAPADARICDTSTAHRVNPNWTYGFAEFSGQFEKIQNANRVAVPGCHATGY
CHHHHHHHHCCCCCCEEECCCCCCCCCCCEEEEHHHHCCHHHHHCCCCEEECCCCCCCHH
IALVRPLIEKGALSADYPLSCHSLTGYSGGGKAMIAEYQNPDREQKFSAPRVYGLALKHK
HHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEECCCCCHHHHCCCCEEEEEECCCC
HLPEMQALTGSNHPPIFTPVVADYYSGMLVTVPLPVSALSQAVNSAEKIANLFSEYYQNS
CCCCHHHHCCCCCCCEEHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
KLITVHPACSLPEDGMLAANTFSGKDSLEIFVYGNETQLLLCARFDNLGKGASGAAVQCM
EEEEECCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHH
NIMLGREETAGLDV
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]