Click here to switch to the map view.

The map label for this gene is ftsZ [H]

Identifier: 126207511

GI number: 126207511

Start: 26459

End: 27670

Strand: Direct

Name: ftsZ [H]

Synonym: APL_0023

Alternate gene names: 126207511

Gene position: 26459-27670 (Clockwise)

Preceding gene: 126207510

Following gene: 126207512

Centisome position: 1.16

GC content: 47.11

Gene sequence:

>1212_bases
ATGTTTGAACCTATTTATGAAACAACGCAAGATGCGGTAATTAAGGTAGTCGGCGTTGGTGGCGGTGGCGGTAATGCACT
AAACCATATGGTGGACGGAAACCTGAATAACGAAGGTGTCGGCGGCGTTGAGTTTTTCTCGGTAAATACCGATGCGCAAG
TATTGCGTACAAGTTCCGTGCGCCAAACGATTCAAATCGGTGCGAATATCACTAAAGGTTTAGGTGCCGGTGCAAATCCG
AATGTAGGTCGTCAAGCAGCGGAAGAAGACCGCGAAGCGTTATCGAATATGCTTGCGGGTGCGGATATGGTATTTATCTC
TGCCGGTATGGGCGGCGGTACGGGTACCGGTGCGGCGCCGGTTATTGCCGATATCGCAAAATCGCAAGGTTCATTAACGG
TTGCCATCGTAACCAAACCGTTCCGTTTCGAAGGTAACAAACGTATGAATTACGCGGAGCAAGGTATCCAAGAGTTATCT
AAGCACGTAGATTCATTAATTATCATCCCTAACGATAAATTATTAAAGGTATTACCTAAAAATACGAAAATGATGGATGC
TTTCAAAGCGGCGAATGATATTTTACGTAACGCCGTTTTAGGTATCACCGATATGATTACCTCTCCGGGGTTAATTAACG
TGGACTTTGCCGACGTGAAAACCGTTATGTCGGAAATGGGACGTGCGATGATGGGTACCGGTATTGCCGAAGGCGAAGAC
CGTGCAGAACATGCGGCACACGATGCGGTGGCAAGCCCGTTATTGGAAGATGTGGATTTATCCGGTGCGAAAGGTATCTT
AGTAAGTATCTCTTCAGGTTTGGATATTGAGTTAAACGAAGTCGATGTGATTATGGATTATATCCACAGTTTTGCCGCTC
CGGATGCGACGATTGTATTCGGTACTTCGGTTTATCCGGAAATGGAAGGTAAACTTCGCGTAACATTAGTGGCGACAGGT
ATCGGTCAAGCGGAAGAATTAACGTTACCGAGAGCGACTGTCGTTCCGCAACCAATGCAACAACCTATGCAACAGCAAGG
CTATCAACAACAAGCGCAACAGCCTCAACAACCTGCTTTTGCACAACAGGGTTACGCTCAGCCGGCGCAATTCGCTCAAC
CGCAACAAGCGGCTCCGAAACCTCAGCAGGTGGATTCTTCCCAAGTTTGGTCTCCTAATTCGATTCCGGGATTTATGAGA
AACGGTCAATAA

Upstream 100 bases:

>100_bases
TCCTTGATATTCTGAGTCGAGGACTGAAAAAAGTAGTTAATGTGGCAAGATCGAATTTTTAAATGTGTTGAGTTGCAAAT
CAGCACGAGGGAGATAAAAA

Downstream 100 bases:

>100_bases
CGCCGTTACCCAAACGGGGAATAAGGATAGAATATGATTAAACAAAGAACATTAAAACAAGCGACTAAAGTCACCGGTAT
CGGTTTGCACAGCGGTAAAA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFEPIYETTQDAVIKVVGVGGGGGNALNHMVDGNLNNEGVGGVEFFSVNTDAQVLRTSSVRQTIQIGANITKGLGAGANP
NVGRQAAEEDREALSNMLAGADMVFISAGMGGGTGTGAAPVIADIAKSQGSLTVAIVTKPFRFEGNKRMNYAEQGIQELS
KHVDSLIIIPNDKLLKVLPKNTKMMDAFKAANDILRNAVLGITDMITSPGLINVDFADVKTVMSEMGRAMMGTGIAEGED
RAEHAAHDAVASPLLEDVDLSGAKGILVSISSGLDIELNEVDVIMDYIHSFAAPDATIVFGTSVYPEMEGKLRVTLVATG
IGQAEELTLPRATVVPQPMQQPMQQQGYQQQAQQPQQPAFAQQGYAQPAQFAQPQQAAPKPQQVDSSQVWSPNSIPGFMR
NGQ

Sequences:

>Translated_403_residues
MFEPIYETTQDAVIKVVGVGGGGGNALNHMVDGNLNNEGVGGVEFFSVNTDAQVLRTSSVRQTIQIGANITKGLGAGANP
NVGRQAAEEDREALSNMLAGADMVFISAGMGGGTGTGAAPVIADIAKSQGSLTVAIVTKPFRFEGNKRMNYAEQGIQELS
KHVDSLIIIPNDKLLKVLPKNTKMMDAFKAANDILRNAVLGITDMITSPGLINVDFADVKTVMSEMGRAMMGTGIAEGED
RAEHAAHDAVASPLLEDVDLSGAKGILVSISSGLDIELNEVDVIMDYIHSFAAPDATIVFGTSVYPEMEGKLRVTLVATG
IGQAEELTLPRATVVPQPMQQPMQQQGYQQQAQQPQQPAFAQQGYAQPAQFAQPQQAAPKPQQVDSSQVWSPNSIPGFMR
NGQ
>Mature_403_residues
MFEPIYETTQDAVIKVVGVGGGGGNALNHMVDGNLNNEGVGGVEFFSVNTDAQVLRTSSVRQTIQIGANITKGLGAGANP
NVGRQAAEEDREALSNMLAGADMVFISAGMGGGTGTGAAPVIADIAKSQGSLTVAIVTKPFRFEGNKRMNYAEQGIQELS
KHVDSLIIIPNDKLLKVLPKNTKMMDAFKAANDILRNAVLGITDMITSPGLINVDFADVKTVMSEMGRAMMGTGIAEGED
RAEHAAHDAVASPLLEDVDLSGAKGILVSISSGLDIELNEVDVIMDYIHSFAAPDATIVFGTSVYPEMEGKLRVTLVATG
IGQAEELTLPRATVVPQPMQQPMQQQGYQQQAQQPQQPAFAQQGYAQPAQFAQPQQAAPKPQQVDSSQVWSPNSIPGFMR
NGQ

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Note=Assembles at the inner surface of the cytoplasmic membrane (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=402, Percent_Identity=59.2039800995025, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 42607; Mature: 42607

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEPIYETTQDAVIKVVGVGGGGGNALNHMVDGNLNNEGVGGVEFFSVNTDAQVLRTSSV
CCCCHHHCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHH
RQTIQIGANITKGLGAGANPNVGRQAAEEDREALSNMLAGADMVFISAGMGGGTGTGAAP
HHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
VIADIAKSQGSLTVAIVTKPFRFEGNKRMNYAEQGIQELSKHVDSLIIIPNDKLLKVLPK
HHHHHHHCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEECCCCEEEECCC
NTKMMDAFKAANDILRNAVLGITDMITSPGLINVDFADVKTVMSEMGRAMMGTGIAEGED
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCH
RAEHAAHDAVASPLLEDVDLSGAKGILVSISSGLDIELNEVDVIMDYIHSFAAPDATIVF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCEEEE
GTSVYPEMEGKLRVTLVATGIGQAEELTLPRATVVPQPMQQPMQQQGYQQQAQQPQQPAF
CCCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCH
AQQGYAQPAQFAQPQQAAPKPQQVDSSQVWSPNSIPGFMRNGQ
HHCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFEPIYETTQDAVIKVVGVGGGGGNALNHMVDGNLNNEGVGGVEFFSVNTDAQVLRTSSV
CCCCHHHCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHH
RQTIQIGANITKGLGAGANPNVGRQAAEEDREALSNMLAGADMVFISAGMGGGTGTGAAP
HHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
VIADIAKSQGSLTVAIVTKPFRFEGNKRMNYAEQGIQELSKHVDSLIIIPNDKLLKVLPK
HHHHHHHCCCCEEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEECCCCEEEECCC
NTKMMDAFKAANDILRNAVLGITDMITSPGLINVDFADVKTVMSEMGRAMMGTGIAEGED
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCH
RAEHAAHDAVASPLLEDVDLSGAKGILVSISSGLDIELNEVDVIMDYIHSFAAPDATIVF
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCEEEE
GTSVYPEMEGKLRVTLVATGIGQAEELTLPRATVVPQPMQQPMQQQGYQQQAQQPQQPAF
CCCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCH
AQQGYAQPAQFAQPQQAAPKPQQVDSSQVWSPNSIPGFMRNGQ
HHCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11443086; 12219091 [H]