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The map label for this gene is ftsA [H]

Identifier: 126207510

GI number: 126207510

Start: 25146

End: 26420

Strand: Direct

Name: ftsA [H]

Synonym: APL_0022

Alternate gene names: 126207510

Gene position: 25146-26420 (Clockwise)

Preceding gene: 126207509

Following gene: 126207511

Centisome position: 1.11

GC content: 43.14

Gene sequence:

>1275_bases
ATGACAAAAATAGCAGAATCCAAAATCATTGTCGGTCTAGATATCGGCACATCAAAAGTTGTCGCCGTAGTCGGTGAGGT
ATTGCCTGACGGCGTGATTAATGTTATCGGTTCGGGTAGTTGCCCGGCCAAAGGCGTTGATCGCGGCGGTGTTATCGACT
TAGATGCGGCGGTAAATTCGATTCAACGTGCGATAGAACAAGCCGAATCTGTTTCCGATTGTCAAATTATCGGCGTAACG
CTTGCGATTTCCGGTCAGCATATTACTGCGTTGAACGAAAGCGGTACCGTACCGCTTTCAGGTACGGTAACAAACGAAGA
TATTGATGCAGCTATTCATATCGCACGTTCGATTAAGTTACCTGACGGATTGGAGACCTTACATATTATTCCGCAGGAAT
ATAAAGTGGACAGATTACCGGCAACCAAAAACCCGGTCGGTTTATCCGGTATGCGTTTACAAGCGCAAGCGCATATCGTC
GCGTGTCATCAGGATTGGTTGCGTAACCTGAAAAATGCGGTTGAGCGAGCGAAATTAAAAGTGGATCAAGTGGTCTTTTC
CGGACTTGCATCAAGTTATTCGGTTTTAACCGAGGATGAAAAAGAATTAGGCGTATGTTTGATCGACATCGGCGGCGGTA
CAATGGATATTCTTGTTTATACCGACGGTGCGTTACGTTTTAGCAAAGTGATTCCTTTTGCCGGTAATAATGTTACCGAT
TATATTGCGCAAGTCTTCACTACTTCTCGCAATGAAGCCGAGAGTATTAAAATCAATTACGGTAGCGCCGTTAATCCTCC
TACGCATAACGCGGATAAGAAAATTGAAGTCGCAGGGCTTGGCGGCCGTATGCCGAGAACCTTTACTAAAGCGCAAGTTG
CTACCGTGACTTCACAATGTTATAGTGATTTGTTAAAAGTCGTAGAAAACGAATTGGTACAATTACGTCATGAATTGCTA
CAAAAAGGCATAAAACAGGAATTAATTGCAGGTTTTGTGCTTACGGGTGGTGGTTCGCAAATCGAAGATATTGTAGAATG
TGCGAGAGAAATTTTCGGCTCTCAGGTAAGAGTCGGATATCCGTTGAATATTACAGGATTGACGGATTACGTAAATAAGC
CGCAATATGCGACAGTACTCGGTCTTTTACAATATAGCCATTATAACTCGGATGAAAAGGGCAATGGCGAAATTAGCGAG
AAAGTAGATAGTATCCTTGATATTCTGAGTCGAGGACTGAAAAAAGTAGTTAATGTGGCAAGATCGAATTTTTAA

Upstream 100 bases:

>100_bases
GGAAAAAAACTTGCTTATGTCGATTTGCGCTACGAACATGGCGCGGCGGTCGGTTTTAGTCCTTTACCTAAATAATTTTT
TGCAAGCATAATATAACGAT

Downstream 100 bases:

>100_bases
ATGTGTTGAGTTGCAAATCAGCACGAGGGAGATAAAAAATGTTTGAACCTATTTATGAAACAACGCAAGATGCGGTAATT
AAGGTAGTCGGCGTTGGTGG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTKIAESKIIVGLDIGTSKVVAVVGEVLPDGVINVIGSGSCPAKGVDRGGVIDLDAAVNSIQRAIEQAESVSDCQIIGVT
LAISGQHITALNESGTVPLSGTVTNEDIDAAIHIARSIKLPDGLETLHIIPQEYKVDRLPATKNPVGLSGMRLQAQAHIV
ACHQDWLRNLKNAVERAKLKVDQVVFSGLASSYSVLTEDEKELGVCLIDIGGGTMDILVYTDGALRFSKVIPFAGNNVTD
YIAQVFTTSRNEAESIKINYGSAVNPPTHNADKKIEVAGLGGRMPRTFTKAQVATVTSQCYSDLLKVVENELVQLRHELL
QKGIKQELIAGFVLTGGGSQIEDIVECAREIFGSQVRVGYPLNITGLTDYVNKPQYATVLGLLQYSHYNSDEKGNGEISE
KVDSILDILSRGLKKVVNVARSNF

Sequences:

>Translated_424_residues
MTKIAESKIIVGLDIGTSKVVAVVGEVLPDGVINVIGSGSCPAKGVDRGGVIDLDAAVNSIQRAIEQAESVSDCQIIGVT
LAISGQHITALNESGTVPLSGTVTNEDIDAAIHIARSIKLPDGLETLHIIPQEYKVDRLPATKNPVGLSGMRLQAQAHIV
ACHQDWLRNLKNAVERAKLKVDQVVFSGLASSYSVLTEDEKELGVCLIDIGGGTMDILVYTDGALRFSKVIPFAGNNVTD
YIAQVFTTSRNEAESIKINYGSAVNPPTHNADKKIEVAGLGGRMPRTFTKAQVATVTSQCYSDLLKVVENELVQLRHELL
QKGIKQELIAGFVLTGGGSQIEDIVECAREIFGSQVRVGYPLNITGLTDYVNKPQYATVLGLLQYSHYNSDEKGNGEISE
KVDSILDILSRGLKKVVNVARSNF
>Mature_423_residues
TKIAESKIIVGLDIGTSKVVAVVGEVLPDGVINVIGSGSCPAKGVDRGGVIDLDAAVNSIQRAIEQAESVSDCQIIGVTL
AISGQHITALNESGTVPLSGTVTNEDIDAAIHIARSIKLPDGLETLHIIPQEYKVDRLPATKNPVGLSGMRLQAQAHIVA
CHQDWLRNLKNAVERAKLKVDQVVFSGLASSYSVLTEDEKELGVCLIDIGGGTMDILVYTDGALRFSKVIPFAGNNVTDY
IAQVFTTSRNEAESIKINYGSAVNPPTHNADKKIEVAGLGGRMPRTFTKAQVATVTSQCYSDLLKVVENELVQLRHELLQ
KGIKQELIAGFVLTGGGSQIEDIVECAREIFGSQVRVGYPLNITGLTDYVNKPQYATVLGLLQYSHYNSDEKGNGEISEK
VDSILDILSRGLKKVVNVARSNF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=419, Percent_Identity=52.0286396181384, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45448; Mature: 45317

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAESKIIVGLDIGTSKVVAVVGEVLPDGVINVIGSGSCPAKGVDRGGVIDLDAAVNS
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEEHHHHHHH
IQRAIEQAESVSDCQIIGVTLAISGQHITALNESGTVPLSGTVTNEDIDAAIHIARSIKL
HHHHHHHHCCCCCCEEEEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCC
PDGLETLHIIPQEYKVDRLPATKNPVGLSGMRLQAQAHIVACHQDWLRNLKNAVERAKLK
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHEEEHHHHHHHHHHHHHHHHHHHH
VDQVVFSGLASSYSVLTEDEKELGVCLIDIGGGTMDILVYTDGALRFSKVIPFAGNNVTD
HHHHHHHHHHHHHHHHCCCCHHCCEEEEEECCCEEEEEEEECCCEEEHHCCCCCCCCHHH
YIAQVFTTSRNEAESIKINYGSAVNPPTHNADKKIEVAGLGGRMPRTFTKAQVATVTSQC
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
YSDLLKVVENELVQLRHELLQKGIKQELIAGFVLTGGGSQIEDIVECAREIFGSQVRVGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEECC
PLNITGLTDYVNKPQYATVLGLLQYSHYNSDEKGNGEISEKVDSILDILSRGLKKVVNVA
CEEECCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSNF
HCCC
>Mature Secondary Structure 
TKIAESKIIVGLDIGTSKVVAVVGEVLPDGVINVIGSGSCPAKGVDRGGVIDLDAAVNS
CCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEEHHHHHHH
IQRAIEQAESVSDCQIIGVTLAISGQHITALNESGTVPLSGTVTNEDIDAAIHIARSIKL
HHHHHHHHCCCCCCEEEEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCC
PDGLETLHIIPQEYKVDRLPATKNPVGLSGMRLQAQAHIVACHQDWLRNLKNAVERAKLK
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEHEEEHHHHHHHHHHHHHHHHHHHH
VDQVVFSGLASSYSVLTEDEKELGVCLIDIGGGTMDILVYTDGALRFSKVIPFAGNNVTD
HHHHHHHHHHHHHHHHCCCCHHCCEEEEEECCCEEEEEEEECCCEEEHHCCCCCCCCHHH
YIAQVFTTSRNEAESIKINYGSAVNPPTHNADKKIEVAGLGGRMPRTFTKAQVATVTSQC
HHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
YSDLLKVVENELVQLRHELLQKGIKQELIAGFVLTGGGSQIEDIVECAREIFGSQVRVGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCEEECC
PLNITGLTDYVNKPQYATVLGLLQYSHYNSDEKGNGEISEKVDSILDILSRGLKKVVNVA
CEEECCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RSNF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]