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The map label for this gene is queC

Identifier: 126174471

GI number: 126174471

Start: 2609240

End: 2609962

Strand: Direct

Name: queC

Synonym: Sbal_2255

Alternate gene names: 126174471

Gene position: 2609240-2609962 (Clockwise)

Preceding gene: 126174469

Following gene: 126174472

Centisome position: 50.89

GC content: 47.72

Gene sequence:

>723_bases
ATGTCAACGAGCTTAGTGTCAAAACCCTTAGCGTCCAAAGCAGTGGTGGTATTTAGTGGCGGACAAGATTCGACAACCTG
TCTTATCCAAGCCCTAACCCAGTACGATGAAGTACACGGGATCACCTTTGACTACGGTCAGCGTCACCGCGAAGAAATTG
AAGTCGCCAAATCCTTAGCAAAACGCTTGAAGATCACCAGCCATAAAGTCATGGATGTCACCTTACTCAATGAGTTAGCG
ATATCGGCGCTTACCCGTGATGCGATTCCCGTTTCACATGAGTTAATGGAAAATGGGCTGCCGAATACTTTTGTGCCTGG
ACGTAATATTCTGTTTTTAACGCTTGCGGGCATTTATGCCTATCAATTAGGCGCTGAAGCGATTATCACCGGCGTATGTG
AAACCGACTTTTCGGGTTACCCAGATTGCCGCAACGATTTTGTTAAAGCGATGGAGTCAGCCTTAGTTCAAGGCATGGAT
AAACAACTTAAGATCATCACGCCCTTAATGTGGCTCAATAAGGCTCAAACCTGGGCGCTGGCGGATAAATATCAGCAACT
CGATCTAGTTCGCCACCATACCCTCACTTGCTATAACGGCGTGATTGGTGATGGTTGTGGCGATTGCCCTGCCTGTCATC
TGCGTAAACGTGGTTTGGATGAGTACATGCAGGATAAAACCGCAGTCATGGCTTCACTCGACGCTAGCGAGCCTAAGGCA
TGA

Upstream 100 bases:

>100_bases
AAAGCCTATTTGATCTAGATCGCCAGAGTTTGCAAGCCCTATGGCCTGAGTTACACTAACGGCCTATTCATGAGTGTTCT
ACGGTTAAGTGAAATCCTTT

Downstream 100 bases:

>100_bases
CACGCAGTCCCTATTGGGTCGCGCTGATAGTGAGTCTGATATGTGCGGGTTTGTATGTCGCAGGCTTAGCCAGTCCTGCT
GTCGACAACCTGCTCGCCTA

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSTSLVSKPLASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELA
ISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMD
KQLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDASEPKA

Sequences:

>Translated_240_residues
MSTSLVSKPLASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELA
ISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMD
KQLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDASEPKA
>Mature_239_residues
STSLVSKPLASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVMDVTLLNELAI
SALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDK
QLKIITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDASEPKA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=222, Percent_Identity=69.3693693693694, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SHEB2 (B8E544)

Other databases:

- EMBL:   CP001252
- RefSeq:   YP_002358191.1
- ProteinModelPortal:   B8E544
- SMR:   B8E544
- GeneID:   7086396
- GenomeReviews:   CP001252_GR
- KEGG:   sbp:Sbal223_2269
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   PRK11106
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26414; Mature: 26282

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSLVSKPLASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLA
CCCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KRLKITSHKVMDVTLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
YQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDKQLKIITPLMWLNKAQTWAL
HHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
ADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDASEPKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STSLVSKPLASKAVVVFSGGQDSTTCLIQALTQYDEVHGITFDYGQRHREEIEVAKSLA
CCCHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
KRLKITSHKVMDVTLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
YQLGAEAIITGVCETDFSGYPDCRNDFVKAMESALVQGMDKQLKIITPLMWLNKAQTWAL
HHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
ADKYQQLDLVRHHTLTCYNGVIGDGCGDCPACHLRKRGLDEYMQDKTAVMASLDASEPKA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA