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The map label for this gene is dnaQ [H]

Identifier: 126174224

GI number: 126174224

Start: 2321708

End: 2322436

Strand: Direct

Name: dnaQ [H]

Synonym: Sbal_2000

Alternate gene names: 126174224

Gene position: 2321708-2322436 (Clockwise)

Preceding gene: 126174222

Following gene: 126174225

Centisome position: 45.28

GC content: 49.11

Gene sequence:

>729_bases
ATGAATATTATCTCTAACGCTAACCGTCAGGTTATTTTGGATACCGAAACCACAGGTATGAACCAGGGCAGCGGCGCCAT
CTATTTAGGCCATAGGATCATCGAGATAGGTTGTGTGGAAGTGGTGAACCGTCGTTTGACGGGGCGTTATTACCACCAAT
ATATCAATCCAGGTCAAGCAATCGATCCAGAAGCCATCGCCGTTCACGGTATTACCGATGAGCGCGTTTCCAAAGAGCCG
CGTTTTCATCAAGTTGCTCAAGACTTTATCAACTTTATCGACGGCGCTGAAATCGTCGCCCATAACGCGAACTTCGACGT
GAGCTTCATGGATCATGAGTTTTCACTGTTGCAGCCGCGTGGACCAAAAACCGCTGATATTTGTCAGATCCTCGATACCT
TAGTCATCGCTAAGTTCCTGCATCCTGGTCAGAAAAACAACCTTGACGCCCTCTGTAAGCGTTATGGCGTGGATACGTCG
CGCCGCGAATATCACGGTGCTTTGCTCGATGCCGAGATCCTCGCCGATGTTTATCTGATCATGACCGGCGGGCAGACAAA
GTTTAATTTGTCTAACGAGGAAGCGGGGCAGGAAGCGGGGGGGATTCAACGTTTTGATCCGCAATCACTTAACCTTAAAG
TGATCGGCGCTTCGGCCGATGAATTGACTATGCATGAACAACGCCTTGATTTAGTCGCGAAATCAGGCAAATGCCTCTGG
AGAGGATAG

Upstream 100 bases:

>100_bases
GAAGATGTGGATCAGTTTTAGTTCAGTCATCAAATTGTTACCATAGCCGGGAATTTCGGCCGAGTATAACCAAAAACTGT
CATAAGAAGCGCATAAAAAA

Downstream 100 bases:

>100_bases
AAAAATCACTATGCCGATGTCGCGCCATAAACCCATTTTAGCGCTTTGCCTTGTTGTCACTACGCTGTTTGCCAGTGTGA
CGTCTGTATTGGCCGTCGAG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MNIISNANRQVILDTETTGMNQGSGAIYLGHRIIEIGCVEVVNRRLTGRYYHQYINPGQAIDPEAIAVHGITDERVSKEP
RFHQVAQDFINFIDGAEIVAHNANFDVSFMDHEFSLLQPRGPKTADICQILDTLVIAKFLHPGQKNNLDALCKRYGVDTS
RREYHGALLDAEILADVYLIMTGGQTKFNLSNEEAGQEAGGIQRFDPQSLNLKVIGASADELTMHEQRLDLVAKSGKCLW
RG

Sequences:

>Translated_242_residues
MNIISNANRQVILDTETTGMNQGSGAIYLGHRIIEIGCVEVVNRRLTGRYYHQYINPGQAIDPEAIAVHGITDERVSKEP
RFHQVAQDFINFIDGAEIVAHNANFDVSFMDHEFSLLQPRGPKTADICQILDTLVIAKFLHPGQKNNLDALCKRYGVDTS
RREYHGALLDAEILADVYLIMTGGQTKFNLSNEEAGQEAGGIQRFDPQSLNLKVIGASADELTMHEQRLDLVAKSGKCLW
RG
>Mature_242_residues
MNIISNANRQVILDTETTGMNQGSGAIYLGHRIIEIGCVEVVNRRLTGRYYHQYINPGQAIDPEAIAVHGITDERVSKEP
RFHQVAQDFINFIDGAEIVAHNANFDVSFMDHEFSLLQPRGPKTADICQILDTLVIAKFLHPGQKNNLDALCKRYGVDTS
RREYHGALLDAEILADVYLIMTGGQTKFNLSNEEAGQEAGGIQRFDPQSLNLKVIGASADELTMHEQRLDLVAKSGKCLW
RG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=239, Percent_Identity=54.8117154811716, Blast_Score=267, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26907; Mature: 26907

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIISNANRQVILDTETTGMNQGSGAIYLGHRIIEIGCVEVVNRRLTGRYYHQYINPGQA
CCCCCCCCCEEEEECCCCCCCCCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
IDPEAIAVHGITDERVSKEPRFHQVAQDFINFIDGAEIVAHNANFDVSFMDHEFSLLQPR
CCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEECCC
GPKTADICQILDTLVIAKFLHPGQKNNLDALCKRYGVDTSRREYHGALLDAEILADVYLI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHHHEEEEE
MTGGQTKFNLSNEEAGQEAGGIQRFDPQSLNLKVIGASADELTMHEQRLDLVAKSGKCLW
EECCCEEEECCCHHCCHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEE
RG
CC
>Mature Secondary Structure
MNIISNANRQVILDTETTGMNQGSGAIYLGHRIIEIGCVEVVNRRLTGRYYHQYINPGQA
CCCCCCCCCEEEEECCCCCCCCCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
IDPEAIAVHGITDERVSKEPRFHQVAQDFINFIDGAEIVAHNANFDVSFMDHEFSLLQPR
CCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCEEEECCC
GPKTADICQILDTLVIAKFLHPGQKNNLDALCKRYGVDTSRREYHGALLDAEILADVYLI
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHHHEEEEE
MTGGQTKFNLSNEEAGQEAGGIQRFDPQSLNLKVIGASADELTMHEQRLDLVAKSGKCLW
EECCCEEEECCCHHCCHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEE
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]