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The map label for this gene is bioD [H]

Identifier: 124265722

GI number: 124265722

Start: 565720

End: 566433

Strand: Direct

Name: bioD [H]

Synonym: Mpe_A0529

Alternate gene names: 124265722

Gene position: 565720-566433 (Clockwise)

Preceding gene: 124265721

Following gene: 124265723

Centisome position: 13.99

GC content: 73.25

Gene sequence:

>714_bases
ATGACGGCACCGCGGACACCCGCCGCGCGCGGCTGGTTCGTGACCGGCACCGACACCGGGGTCGGCAAGACCCGCGCGAG
CGTCGCGCTGCTGCGGGCGCTGCGCGCGCGACACGCGCGCTGTGTCGGCATGAAGCCGGTCGCGGCAGGCACCGAGCCGG
CACCCGATGGCGGCGAGCGAGAGAACGAGGATGTGCTGGCGCTGCGTGCCGCGGGCACGGCACGCGTGGCCGCTGCGCTC
GACAACCCGGTGCGTCTCCACGACGCGATGTCGCCGCACCTCGCCGCGCGGCGCGCCGGCCGAACGATCGAGATCGAACC
GCTGGTCGCGGCCTACCGCGCGCTGGCCGCACAAGCCGATGCGGTGGTGGTCGAAGGCGCAGGAGGCTTTCTCGTGCCCT
TGTCCGACACGCTGACCGGTGCCGACCTCGCCGCGGCGCTCGGCCTGCCGGTGATCCTCGTCGTCGGCCTGCGCCTGGGG
TGCCTGAACCACGCGCTGTTGACGCGTGACGCGATCCGGCAACGCGGCCTGCCGCTGGCCGGCTGGATCGTCAGCCGGCT
CGATCCCGCGATGCCGGAGCAGGACGCCAACGTCGACTACCTGCGCCGGCAGCTCGATGCACCCCTGTTGGCCGACTGGC
CCTGGCAGCCCGATGCCGACCCGGGCACGCTGCTGTTGCAACTTCCCCCTGAGCCAGTTCTCGATGCCGCCTGA

Upstream 100 bases:

>100_bases
TCGGCAACACGCTGTACTTCATGCCGCCCTATGTGCTGGACGACGGGGCGCTGGAGCAACTGGCCGGCGGTGCGCTGCGC
GCGCTCGAGGTCGCGCTGGC

Downstream 100 bases:

>100_bases
CATCCACGACGTTTTCGGGTCGGCGCTCGCCGCGCTCGACACGCAGCAACTGCGCCGCCACCGCCGCGTGGTCTCGGCGC
TCGACGGCGCGATGGTGCAG

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTAPRTPAARGWFVTGTDTGVGKTRASVALLRALRARHARCVGMKPVAAGTEPAPDGGERENEDVLALRAAGTARVAAAL
DNPVRLHDAMSPHLAARRAGRTIEIEPLVAAYRALAAQADAVVVEGAGGFLVPLSDTLTGADLAAALGLPVILVVGLRLG
CLNHALLTRDAIRQRGLPLAGWIVSRLDPAMPEQDANVDYLRRQLDAPLLADWPWQPDADPGTLLLQLPPEPVLDAA

Sequences:

>Translated_237_residues
MTAPRTPAARGWFVTGTDTGVGKTRASVALLRALRARHARCVGMKPVAAGTEPAPDGGERENEDVLALRAAGTARVAAAL
DNPVRLHDAMSPHLAARRAGRTIEIEPLVAAYRALAAQADAVVVEGAGGFLVPLSDTLTGADLAAALGLPVILVVGLRLG
CLNHALLTRDAIRQRGLPLAGWIVSRLDPAMPEQDANVDYLRRQLDAPLLADWPWQPDADPGTLLLQLPPEPVLDAA
>Mature_236_residues
TAPRTPAARGWFVTGTDTGVGKTRASVALLRALRARHARCVGMKPVAAGTEPAPDGGERENEDVLALRAAGTARVAAALD
NPVRLHDAMSPHLAARRAGRTIEIEPLVAAYRALAAQADAVVVEGAGGFLVPLSDTLTGADLAAALGLPVILVVGLRLGC
LNHALLTRDAIRQRGLPLAGWIVSRLDPAMPEQDANVDYLRRQLDAPLLADWPWQPDADPGTLLLQLPPEPVLDAA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=207, Percent_Identity=46.8599033816425, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI87081944, Length=211, Percent_Identity=36.4928909952607, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24870; Mature: 24739

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRTPAARGWFVTGTDTGVGKTRASVALLRALRARHARCVGMKPVAAGTEPAPDGGER
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ENEDVLALRAAGTARVAAALDNPVRLHDAMSPHLAARRAGRTIEIEPLVAAYRALAAQAD
CCCCEEEEECCCCHHHHHHHCCCEEHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
AVVVEGAGGFLVPLSDTLTGADLAAALGLPVILVVGLRLGCLNHALLTRDAIRQRGLPLA
EEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GWIVSRLDPAMPEQDANVDYLRRQLDAPLLADWPWQPDADPGTLLLQLPPEPVLDAA
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TAPRTPAARGWFVTGTDTGVGKTRASVALLRALRARHARCVGMKPVAAGTEPAPDGGER
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ENEDVLALRAAGTARVAAALDNPVRLHDAMSPHLAARRAGRTIEIEPLVAAYRALAAQAD
CCCCEEEEECCCCHHHHHHHCCCEEHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
AVVVEGAGGFLVPLSDTLTGADLAAALGLPVILVVGLRLGCLNHALLTRDAIRQRGLPLA
EEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GWIVSRLDPAMPEQDANVDYLRRQLDAPLLADWPWQPDADPGTLLLQLPPEPVLDAA
HHHHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA