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The map label for this gene is pgk [H]

Identifier: 124265482

GI number: 124265482

Start: 313071

End: 314264

Strand: Direct

Name: pgk [H]

Synonym: Mpe_A0289

Alternate gene names: 124265482

Gene position: 313071-314264 (Clockwise)

Preceding gene: 124265481

Following gene: 124265483

Centisome position: 7.74

GC content: 68.68

Gene sequence:

>1194_bases
TTGAAGGTTCTGCGGTTCTCCGATCTCATCCAGCAAGGTCGCGTCGCCGGCCAACGTGTCTTCATCCGGGCCGATCTGAA
CGTGCCGCAGGACGACGCCGGGCGCATCACCGAGGACACCCGCATCCGCGCCTCGATCCCCTGCATCGAGATGGCGCTGG
CGGCCGGTGCGGCCGTGATGGTGACCTCGCACCTGGGCCGTCCGACCGAGGGCGAGTTCAAGGCCGAGGACTCCCTGGCG
CCGGTCGCGCGCCGTCTGGCCGAGTTGCTGGGCCGCAAGGTGCCGCTGCTGCAGGACTGGACCGGCGGTGTCGAAGTCGC
GCCGGGTGAACTGGTGCTGCTCGAGAACTGCCGCGTCAACAAGGGCGAGAAGAAGAACGACGAAACGCTGGCCCGGAAGA
TGGCCGCGCTCTGCGACATCTTCGTGCACGACGCCTTCGGCACCGCGCACCGCGCCGAGGCCTCGACCTATGGCATTGCG
CAGTTCGCCAAGGTGGCCTGTGCCGGCCCGCTGCTGGCGGCCGAGATCGACGCCATCACCAAGGCCCTGAAGAGCCCGAA
GCGCCCGCTGGTGGCCATCGTGGCGGGCTCCAAGGTCAGCACCAAGCTGTCGATCCTGAAGTCGCTGGCGGCCAACGTCG
ACCAGCTGATCGTCGGCGGCGGCATCGCCAACACGTTCATGCTGGCGGTCGGTCTGTCCATCGGCAAGTCGCTGGCCGAG
CCCGATCTGGTGGATGAGGCGCGCGCCATCATCGACATGATGAAGGCGCGTGGCGCCGCGGTGCCGATCCCGATCGACGT
GGTCGTGGCCGACGAGTTCTCTGCCATCGCACGCGCCAACAAGGTGACCGCCACCGAGGTGCGGCCCGATGACCTGATCC
TCGACATCGGCCCGCGCACCGCGGCCGAGCTGGCCGGCATCATCGCGCGCGCCGGCACGGTGGTCTGGAACGGGCCGATG
GGCGTGTTCGAATACGACCAGTTCGCCGGCGGAACGCGCACGCTGGCTGCGGCCATCGCCCATTCGCCGGCTTTCAGCAT
CGCCGGCGGCGGCGACACACTGGCGGCGATCGCAAAGTACGGCATCGAGAAGGACATCGGCTACATCTCCACCGGTGGCG
GCGCCTTCCTCGAGGTGCTGGAGGGCAAGACCCTGCCGGCCTTCGAGATCCTCGAGCAGCGGGCCGCCGGCTGA

Upstream 100 bases:

>100_bases
GCTGCCCCTGCGCTTGGTGCTGGGCTGGTAGTCCACGGCGGCCGGAACGCGCGCCACTCGCCATTCCCTTCGTTTTCCCC
ACCATCCGAGGAGTCAGTCT

Downstream 100 bases:

>100_bases
GCGGCATGACGACACGGGGCGCTGCGGCGCCCCTCGCTTCATCGGAATCTTCTTCACATGACCATGCACCGCGCCACCAA
GATCGTCGCCACCCTCGGCC

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKVLRFSDLIQQGRVAGQRVFIRADLNVPQDDAGRITEDTRIRASIPCIEMALAAGAAVMVTSHLGRPTEGEFKAEDSLA
PVARRLAELLGRKVPLLQDWTGGVEVAPGELVLLENCRVNKGEKKNDETLARKMAALCDIFVHDAFGTAHRAEASTYGIA
QFAKVACAGPLLAAEIDAITKALKSPKRPLVAIVAGSKVSTKLSILKSLAANVDQLIVGGGIANTFMLAVGLSIGKSLAE
PDLVDEARAIIDMMKARGAAVPIPIDVVVADEFSAIARANKVTATEVRPDDLILDIGPRTAAELAGIIARAGTVVWNGPM
GVFEYDQFAGGTRTLAAAIAHSPAFSIAGGGDTLAAIAKYGIEKDIGYISTGGGAFLEVLEGKTLPAFEILEQRAAG

Sequences:

>Translated_397_residues
MKVLRFSDLIQQGRVAGQRVFIRADLNVPQDDAGRITEDTRIRASIPCIEMALAAGAAVMVTSHLGRPTEGEFKAEDSLA
PVARRLAELLGRKVPLLQDWTGGVEVAPGELVLLENCRVNKGEKKNDETLARKMAALCDIFVHDAFGTAHRAEASTYGIA
QFAKVACAGPLLAAEIDAITKALKSPKRPLVAIVAGSKVSTKLSILKSLAANVDQLIVGGGIANTFMLAVGLSIGKSLAE
PDLVDEARAIIDMMKARGAAVPIPIDVVVADEFSAIARANKVTATEVRPDDLILDIGPRTAAELAGIIARAGTVVWNGPM
GVFEYDQFAGGTRTLAAAIAHSPAFSIAGGGDTLAAIAKYGIEKDIGYISTGGGAFLEVLEGKTLPAFEILEQRAAG
>Mature_397_residues
MKVLRFSDLIQQGRVAGQRVFIRADLNVPQDDAGRITEDTRIRASIPCIEMALAAGAAVMVTSHLGRPTEGEFKAEDSLA
PVARRLAELLGRKVPLLQDWTGGVEVAPGELVLLENCRVNKGEKKNDETLARKMAALCDIFVHDAFGTAHRAEASTYGIA
QFAKVACAGPLLAAEIDAITKALKSPKRPLVAIVAGSKVSTKLSILKSLAANVDQLIVGGGIANTFMLAVGLSIGKSLAE
PDLVDEARAIIDMMKARGAAVPIPIDVVVADEFSAIARANKVTATEVRPDDLILDIGPRTAAELAGIIARAGTVVWNGPM
GVFEYDQFAGGTRTLAAAIAHSPAFSIAGGGDTLAAIAKYGIEKDIGYISTGGGAFLEVLEGKTLPAFEILEQRAAG

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=406, Percent_Identity=38.6699507389163, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI4505763, Length=406, Percent_Identity=36.2068965517241, Blast_Score=248, Evalue=1e-65,
Organism=Escherichia coli, GI1789294, Length=395, Percent_Identity=61.5189873417721, Blast_Score=464, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI17508823, Length=409, Percent_Identity=41.320293398533, Blast_Score=287, Evalue=6e-78,
Organism=Saccharomyces cerevisiae, GI6319857, Length=411, Percent_Identity=39.1727493917275, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI17136394, Length=411, Percent_Identity=38.9294403892944, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24581203, Length=400, Percent_Identity=38, Blast_Score=234, Evalue=6e-62,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41558; Mature: 41558

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLRFSDLIQQGRVAGQRVFIRADLNVPQDDAGRITEDTRIRASIPCIEMALAAGAAVM
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHEE
VTSHLGRPTEGEFKAEDSLAPVARRLAELLGRKVPLLQDWTGGVEVAPGELVLLENCRVN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCEEEEECCCCC
KGEKKNDETLARKMAALCDIFVHDAFGTAHRAEASTYGIAQFAKVACAGPLLAAEIDAIT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
KALKSPKRPLVAIVAGSKVSTKLSILKSLAANVDQLIVGGGIANTFMLAVGLSIGKSLAE
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHCC
PDLVDEARAIIDMMKARGAAVPIPIDVVVADEFSAIARANKVTATEVRPDDLILDIGPRT
CCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHCCCCEEECCCCCCEEEECCCCH
AAELAGIIARAGTVVWNGPMGVFEYDQFAGGTRTLAAAIAHSPAFSIAGGGDTLAAIAKY
HHHHHHHHHHCCEEEECCCCCCEEHHHHCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHH
GIEKDIGYISTGGGAFLEVLEGKTLPAFEILEQRAAG
CCHHCCCEEECCCHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKVLRFSDLIQQGRVAGQRVFIRADLNVPQDDAGRITEDTRIRASIPCIEMALAAGAAVM
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCHHHHHHHCCHHEE
VTSHLGRPTEGEFKAEDSLAPVARRLAELLGRKVPLLQDWTGGVEVAPGELVLLENCRVN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCEEECCCCEEEEECCCCC
KGEKKNDETLARKMAALCDIFVHDAFGTAHRAEASTYGIAQFAKVACAGPLLAAEIDAIT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
KALKSPKRPLVAIVAGSKVSTKLSILKSLAANVDQLIVGGGIANTFMLAVGLSIGKSLAE
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHCC
PDLVDEARAIIDMMKARGAAVPIPIDVVVADEFSAIARANKVTATEVRPDDLILDIGPRT
CCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHCCCCEEECCCCCCEEEECCCCH
AAELAGIIARAGTVVWNGPMGVFEYDQFAGGTRTLAAAIAHSPAFSIAGGGDTLAAIAKY
HHHHHHHHHHCCEEEECCCCCCEEHHHHCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHH
GIEKDIGYISTGGGAFLEVLEGKTLPAFEILEQRAAG
CCHHCCCEEECCCHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA