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The map label for this gene is secF [H]

Identifier: 124265471

GI number: 124265471

Start: 302387

End: 303421

Strand: Direct

Name: secF [H]

Synonym: Mpe_A0278

Alternate gene names: 124265471

Gene position: 302387-303421 (Clockwise)

Preceding gene: 124265470

Following gene: 124265472

Centisome position: 7.48

GC content: 63.77

Gene sequence:

>1035_bases
ATGGAGTTCTTCCGCATCAAGCGCGACATCCCGTTCATGAAGCACGCGTTGATCTTCAACGTCGTGTCCTTCGTGACCTT
TGCCGCCGCCGTGTTCTTCCTCGTGACGCGCGGTCTGCACCTGTCGATCGAGTTCACCGGCGGCACGGTGCTCGAGGTCG
AGTACGCCAAGACGGCCGACGTGCCCAAGGTGCGCAGTGCGGTCGAGGCGCTCGGTTTCGGTGAGGTGCAGGTGCAGAAC
TTCGGCACCTCGCGCGACGTACTGGTCCGGCTGCCGTTGCGGGGCGACGTCAAGCAGCAGGAGGTGGTGGGCCGTGTGTT
CAGCGCGCTGTGCGCGGCCGAGGGCGGTCAGGTCACGCAGTCGCAATCGGTCAGCGACAAGGGCGAGTCGGTCAGCGCGC
AGGTCTGCGACGCCGGCGGCGCGCAACCGGTGATGCTCAAGCGCAGCGAGTTCGTCGGGCCGCAGGTCGGCAAGGAACTG
GCGACCGACGGTGCGATGGCGCTGGGCTTTGTCGTCATCGGCATCATGATCTATCTTGCGATCCGCTTCGAATGGAAGTT
CGCGGTCGCGGCGATCGTCGCCAACCTGCATGACGTGATCATCATCCTGGGCTTCTTCGCCTTCTTCCAGTGGGAATTCT
CTCTGTCGGTGCTGGCGGCCGTGCTGGCGGTGCTGGGCTATTCGGTCAACGAGTCGGTGGTCATCTTCGACCGGATTCGC
GAGGCCTTCCGCCGCTATCGCAAGATGAACACGCACCAGGTGATCGACCATGCGATCACCTCGACCATGAGCCGCACCAT
CATCACGCACGGGTCGACGCAGATGATGGTGTTGTCGATGCTGGTGTTCGGCGGTGCGACGCTGCACTACTTCGCAGTCG
CACTGACGATCGGCATCTTGTTCGGCATCTACTCTTCGGTGTTCGTCGCCGCGGCCATTGCGATGTGGCTGGGCGTCAAG
CGGGAGGATCTGATGAAGGCGGGCAGCGTCAAGGGCGGCGATCCCGACGACCCGAATGCCGGGGCCGTGGTGTAG

Upstream 100 bases:

>100_bases
GCGGCGCAAGAAGCTCAAGGGCGTGTCGATCGGTCAGGTATGGCGTCCGGACGGCGCTGTGCCGCCGGCGGCCCAGGCCT
GAGTAGAAGGAGACGGTTCC

Downstream 100 bases:

>100_bases
AGTTGAAACAGTCTGTCTAATCACCGTCCGCCCCTATCCTCCATGGCCACCCCAGCCGCCCCATCCGCCCTGGCCGCTCA
AGCGCGGCGGGTGTATATGG

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MEFFRIKRDIPFMKHALIFNVVSFVTFAAAVFFLVTRGLHLSIEFTGGTVLEVEYAKTADVPKVRSAVEALGFGEVQVQN
FGTSRDVLVRLPLRGDVKQQEVVGRVFSALCAAEGGQVTQSQSVSDKGESVSAQVCDAGGAQPVMLKRSEFVGPQVGKEL
ATDGAMALGFVVIGIMIYLAIRFEWKFAVAAIVANLHDVIIILGFFAFFQWEFSLSVLAAVLAVLGYSVNESVVIFDRIR
EAFRRYRKMNTHQVIDHAITSTMSRTIITHGSTQMMVLSMLVFGGATLHYFAVALTIGILFGIYSSVFVAAAIAMWLGVK
REDLMKAGSVKGGDPDDPNAGAVV

Sequences:

>Translated_344_residues
MEFFRIKRDIPFMKHALIFNVVSFVTFAAAVFFLVTRGLHLSIEFTGGTVLEVEYAKTADVPKVRSAVEALGFGEVQVQN
FGTSRDVLVRLPLRGDVKQQEVVGRVFSALCAAEGGQVTQSQSVSDKGESVSAQVCDAGGAQPVMLKRSEFVGPQVGKEL
ATDGAMALGFVVIGIMIYLAIRFEWKFAVAAIVANLHDVIIILGFFAFFQWEFSLSVLAAVLAVLGYSVNESVVIFDRIR
EAFRRYRKMNTHQVIDHAITSTMSRTIITHGSTQMMVLSMLVFGGATLHYFAVALTIGILFGIYSSVFVAAAIAMWLGVK
REDLMKAGSVKGGDPDDPNAGAVV
>Mature_344_residues
MEFFRIKRDIPFMKHALIFNVVSFVTFAAAVFFLVTRGLHLSIEFTGGTVLEVEYAKTADVPKVRSAVEALGFGEVQVQN
FGTSRDVLVRLPLRGDVKQQEVVGRVFSALCAAEGGQVTQSQSVSDKGESVSAQVCDAGGAQPVMLKRSEFVGPQVGKEL
ATDGAMALGFVVIGIMIYLAIRFEWKFAVAAIVANLHDVIIILGFFAFFQWEFSLSVLAAVLAVLGYSVNESVVIFDRIR
EAFRRYRKMNTHQVIDHAITSTMSRTIITHGSTQMMVLSMLVFGGATLHYFAVALTIGILFGIYSSVFVAAAIAMWLGVK
REDLMKAGSVKGGDPDDPNAGAVV

Specific function: Involved in protein export [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=318, Percent_Identity=37.7358490566038, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 37350; Mature: 37350

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFRIKRDIPFMKHALIFNVVSFVTFAAAVFFLVTRGLHLSIEFTGGTVLEVEYAKTAD
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCC
VPKVRSAVEALGFGEVQVQNFGTSRDVLVRLPLRGDVKQQEVVGRVFSALCAAEGGQVTQ
CHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SQSVSDKGESVSAQVCDAGGAQPVMLKRSEFVGPQVGKELATDGAMALGFVVIGIMIYLA
CCCCCCCCCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
IRFEWKFAVAAIVANLHDVIIILGFFAFFQWEFSLSVLAAVLAVLGYSVNESVVIFDRIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
EAFRRYRKMNTHQVIDHAITSTMSRTIITHGSTQMMVLSMLVFGGATLHYFAVALTIGIL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FGIYSSVFVAAAIAMWLGVKREDLMKAGSVKGGDPDDPNAGAVV
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEFFRIKRDIPFMKHALIFNVVSFVTFAAAVFFLVTRGLHLSIEFTGGTVLEVEYAKTAD
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCC
VPKVRSAVEALGFGEVQVQNFGTSRDVLVRLPLRGDVKQQEVVGRVFSALCAAEGGQVTQ
CHHHHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
SQSVSDKGESVSAQVCDAGGAQPVMLKRSEFVGPQVGKELATDGAMALGFVVIGIMIYLA
CCCCCCCCCCCCHHHHCCCCCCCEEEEHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
IRFEWKFAVAAIVANLHDVIIILGFFAFFQWEFSLSVLAAVLAVLGYSVNESVVIFDRIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHH
EAFRRYRKMNTHQVIDHAITSTMSRTIITHGSTQMMVLSMLVFGGATLHYFAVALTIGIL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FGIYSSVFVAAAIAMWLGVKREDLMKAGSVKGGDPDDPNAGAVV
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]