Click here to switch to the map view.

The map label for this gene is secD [H]

Identifier: 124265470

GI number: 124265470

Start: 300488

End: 302368

Strand: Direct

Name: secD [H]

Synonym: Mpe_A0277

Alternate gene names: 124265470

Gene position: 300488-302368 (Clockwise)

Preceding gene: 124265469

Following gene: 124265471

Centisome position: 7.43

GC content: 67.57

Gene sequence:

>1881_bases
ATGAACCGCTACCCATGGTGGAAGTACGCGATCCTGGCGATCGCGCTGCTGGTCGGGCTGGTCTATACCTTGCCCAACTT
CTTCGGTGAGGCACCTGCCGTGCAGGTGTCGAGTGGCAAGGCCACGCTGAAGGTCGACGCGACGGTGGTGCCGCGCGTCG
AGCAGGCCTTGCAGGCGGCCGGACTGCAGGCCGATTTCGTGCAACTCGACGGTGCGTCGATCAAGGCACGCTTTCGCGAC
ACCGATGCGCAGATCAAGGCCAAGGACGCCATTGCCAAGGCCTTGAACCCTGACCCGGCCGATCCGGGCTACATCGTCGC
GCTGAACCTGCTGTCGCGTTCACCGACCTGGCTGCGATCGCTGCATGCGCTGCCGATGTACCTGGGCCTCGACCTGCGCG
GCGGGGTGCATTTCCTGATGCAGGTCGACATGAAGGCGGCGCTCACCAAGCGCGCCGATGTGCTGACCGGCGACATCCGC
AGCCTGCTGCGCGACAAGAGCATCCGCCACGCCGGCATCGCGCGTGAAGGCAACACGGTCACGATCGCCTTCCGCGACGC
GGCGACGCGCACCGCCGCGCGGGCGGTGCTGACCGAGCCGCTGCCCGACCTGCAGTGGTCCGAGGCGGCCCGTGACAGTG
AATTCACGCTGACCGGCAGCCTGAAGGCCGAGGCGGCGCGCCGCGTGCAGGATCAGGCCATCAAGCAGAACATCACCACG
CTGCACAATCGGATCAATGAACTCGGCGTGGCCGAGCCGGTGATCCAGCAGCAGGGCGCGGACCGCGTGGTGGTGCAGTT
GCCGGGCGTGCAGGACACGGCGAAGGCGAAGGACATCATCGGCCGGACCGCGACGCTCGAACTGCGCATGGTGGACGACA
GCGCCGAGGCGGCCGCCGCCGCGACCGGCAGCGGGCCGGTGCCGTTCGGGGCCGAGCGCTACGTGGAGCGCGGCGGTGCC
GCGCTGATCGTCAAGCGCCAGGTCATCCTCACCGGTGACAGCCTGACCGACGCGCAACCCGGTTTCGACGGCCAGACGCA
GGAACCGGCCGTGCACCTGACCGTGGACGCCAAGGGCGCACGCATCATGCGCGACGTCTCGCGCGACAACGTCGGCAAGC
GCATGGCGATCCTGCTGTTCGAGAAGGGCAAGGGCGAGGTCGTGACGGCTCCGGTGATTCGCGGTGAACTCGGCTCGCGC
TTCCAGATCTCGGGCCGCATGACGACGCAGGAGGCGAGCGATACGGCGCTGCTGCTGCGTGCCGGTTCGCTGGCGGCGCC
GATGGAGATCGTCGAGGAGCGGACCATCGGTCCGAGCCTTGGCGCCGAGAACATCGACAAGGGCTTCAACAGCGTGATCT
ACGGCTTTGCCGCGATTGCCGCGTTCATGTGCGCCTACTACCTGCTGTTCGGCGTGTTCTCGACCATTGCGCTGGCGGTG
AACCTGCTGCTGCTGGTGGCGGTGCTGTCGATGCTGCAGGCCACGCTCACATTGCCCGGCATCGCGGCGATCGCGCTGAC
GCTGGGGATGGCGATCGACGCCAACGTGCTGATCAACGAACGGGTGCGCGAGGAACTGCGCGCCGGCGCTTCGCCGCAGG
CCGCGATCCACACCGGCTACGAGCGCGCCTGGGCCACGATCTTCGATTCGAACATCACCACGCTGATTGCGGGCGTTGCG
CTGCTGGCCTTCGGCTCAGGTCCTGTCCGCGGCTTCGCGGTTGTGCACTGTCTCGGCATCCTGACCTCGATGTTCTCCGC
GGTGCTGTTCTCGCGTGGTCTGGTGAATCTCTGGTACGGGCGGCGCAAGAAGCTCAAGGGCGTGTCGATCGGTCAGGTAT
GGCGTCCGGACGGCGCTGTGCCGCCGGCGGCCCAGGCCTGA

Upstream 100 bases:

>100_bases
CGAAGGCCGCGGTCACCGCTGGGTGTCGCGGCCTTTCGTGCAAACAAGGGCGCCGTGTGGCACGGTGCCAGGACGGGGGG
TCGCCCCCGAGGATGCTGCA

Downstream 100 bases:

>100_bases
GTAGAAGGAGACGGTTCCATGGAGTTCTTCCGCATCAAGCGCGACATCCCGTTCATGAAGCACGCGTTGATCTTCAACGT
CGTGTCCTTCGTGACCTTTG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MNRYPWWKYAILAIALLVGLVYTLPNFFGEAPAVQVSSGKATLKVDATVVPRVEQALQAAGLQADFVQLDGASIKARFRD
TDAQIKAKDAIAKALNPDPADPGYIVALNLLSRSPTWLRSLHALPMYLGLDLRGGVHFLMQVDMKAALTKRADVLTGDIR
SLLRDKSIRHAGIAREGNTVTIAFRDAATRTAARAVLTEPLPDLQWSEAARDSEFTLTGSLKAEAARRVQDQAIKQNITT
LHNRINELGVAEPVIQQQGADRVVVQLPGVQDTAKAKDIIGRTATLELRMVDDSAEAAAAATGSGPVPFGAERYVERGGA
ALIVKRQVILTGDSLTDAQPGFDGQTQEPAVHLTVDAKGARIMRDVSRDNVGKRMAILLFEKGKGEVVTAPVIRGELGSR
FQISGRMTTQEASDTALLLRAGSLAAPMEIVEERTIGPSLGAENIDKGFNSVIYGFAAIAAFMCAYYLLFGVFSTIALAV
NLLLLVAVLSMLQATLTLPGIAAIALTLGMAIDANVLINERVREELRAGASPQAAIHTGYERAWATIFDSNITTLIAGVA
LLAFGSGPVRGFAVVHCLGILTSMFSAVLFSRGLVNLWYGRRKKLKGVSIGQVWRPDGAVPPAAQA

Sequences:

>Translated_626_residues
MNRYPWWKYAILAIALLVGLVYTLPNFFGEAPAVQVSSGKATLKVDATVVPRVEQALQAAGLQADFVQLDGASIKARFRD
TDAQIKAKDAIAKALNPDPADPGYIVALNLLSRSPTWLRSLHALPMYLGLDLRGGVHFLMQVDMKAALTKRADVLTGDIR
SLLRDKSIRHAGIAREGNTVTIAFRDAATRTAARAVLTEPLPDLQWSEAARDSEFTLTGSLKAEAARRVQDQAIKQNITT
LHNRINELGVAEPVIQQQGADRVVVQLPGVQDTAKAKDIIGRTATLELRMVDDSAEAAAAATGSGPVPFGAERYVERGGA
ALIVKRQVILTGDSLTDAQPGFDGQTQEPAVHLTVDAKGARIMRDVSRDNVGKRMAILLFEKGKGEVVTAPVIRGELGSR
FQISGRMTTQEASDTALLLRAGSLAAPMEIVEERTIGPSLGAENIDKGFNSVIYGFAAIAAFMCAYYLLFGVFSTIALAV
NLLLLVAVLSMLQATLTLPGIAAIALTLGMAIDANVLINERVREELRAGASPQAAIHTGYERAWATIFDSNITTLIAGVA
LLAFGSGPVRGFAVVHCLGILTSMFSAVLFSRGLVNLWYGRRKKLKGVSIGQVWRPDGAVPPAAQA
>Mature_626_residues
MNRYPWWKYAILAIALLVGLVYTLPNFFGEAPAVQVSSGKATLKVDATVVPRVEQALQAAGLQADFVQLDGASIKARFRD
TDAQIKAKDAIAKALNPDPADPGYIVALNLLSRSPTWLRSLHALPMYLGLDLRGGVHFLMQVDMKAALTKRADVLTGDIR
SLLRDKSIRHAGIAREGNTVTIAFRDAATRTAARAVLTEPLPDLQWSEAARDSEFTLTGSLKAEAARRVQDQAIKQNITT
LHNRINELGVAEPVIQQQGADRVVVQLPGVQDTAKAKDIIGRTATLELRMVDDSAEAAAAATGSGPVPFGAERYVERGGA
ALIVKRQVILTGDSLTDAQPGFDGQTQEPAVHLTVDAKGARIMRDVSRDNVGKRMAILLFEKGKGEVVTAPVIRGELGSR
FQISGRMTTQEASDTALLLRAGSLAAPMEIVEERTIGPSLGAENIDKGFNSVIYGFAAIAAFMCAYYLLFGVFSTIALAV
NLLLLVAVLSMLQATLTLPGIAAIALTLGMAIDANVLINERVREELRAGASPQAAIHTGYERAWATIFDSNITTLIAGVA
LLAFGSGPVRGFAVVHCLGILTSMFSAVLFSRGLVNLWYGRRKKLKGVSIGQVWRPDGAVPPAAQA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=627, Percent_Identity=44.6570972886762, Blast_Score=517, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66889; Mature: 66889

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYPWWKYAILAIALLVGLVYTLPNFFGEAPAVQVSSGKATLKVDATVVPRVEQALQAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCEEHHHHHHHHHHC
GLQADFVQLDGASIKARFRDTDAQIKAKDAIAKALNPDPADPGYIVALNLLSRSPTWLRS
CCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCCHHHHH
LHALPMYLGLDLRGGVHFLMQVDMKAALTKRADVLTGDIRSLLRDKSIRHAGIAREGNTV
HHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEE
TIAFRDAATRTAARAVLTEPLPDLQWSEAARDSEFTLTGSLKAEAARRVQDQAIKQNITT
EEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LHNRINELGVAEPVIQQQGADRVVVQLPGVQDTAKAKDIIGRTATLELRMVDDSAEAAAA
HHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHCCEEEEEEEEECCCCHHHHC
ATGSGPVPFGAERYVERGGAALIVKRQVILTGDSLTDAQPGFDGQTQEPAVHLTVDAKGA
CCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCH
RIMRDVSRDNVGKRMAILLFEKGKGEVVTAPVIRGELGSRFQISGRMTTQEASDTALLLR
HHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCCCCCCCEEEECCCEECCCCCCCEEEEE
AGSLAAPMEIVEERTIGPSLGAENIDKGFNSVIYGFAAIAAFMCAYYLLFGVFSTIALAV
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLLVAVLSMLQATLTLPGIAAIALTLGMAIDANVLINERVREELRAGASPQAAIHTGY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCH
ERAWATIFDSNITTLIAGVALLAFGSGPVRGFAVVHCLGILTSMFSAVLFSRGLVNLWYG
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
RRKKLKGVSIGQVWRPDGAVPPAAQA
CHHHCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MNRYPWWKYAILAIALLVGLVYTLPNFFGEAPAVQVSSGKATLKVDATVVPRVEQALQAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCEEHHHHHHHHHHC
GLQADFVQLDGASIKARFRDTDAQIKAKDAIAKALNPDPADPGYIVALNLLSRSPTWLRS
CCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCCHHHHH
LHALPMYLGLDLRGGVHFLMQVDMKAALTKRADVLTGDIRSLLRDKSIRHAGIAREGNTV
HHHHHHHCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCEE
TIAFRDAATRTAARAVLTEPLPDLQWSEAARDSEFTLTGSLKAEAARRVQDQAIKQNITT
EEEECCHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
LHNRINELGVAEPVIQQQGADRVVVQLPGVQDTAKAKDIIGRTATLELRMVDDSAEAAAA
HHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHCCEEEEEEEEECCCCHHHHC
ATGSGPVPFGAERYVERGGAALIVKRQVILTGDSLTDAQPGFDGQTQEPAVHLTVDAKGA
CCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCH
RIMRDVSRDNVGKRMAILLFEKGKGEVVTAPVIRGELGSRFQISGRMTTQEASDTALLLR
HHHHHHHHCCCCCEEEEEEEECCCCCEEECCCCCCCCCCEEEECCCEECCCCCCCEEEEE
AGSLAAPMEIVEERTIGPSLGAENIDKGFNSVIYGFAAIAAFMCAYYLLFGVFSTIALAV
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLLLVAVLSMLQATLTLPGIAAIALTLGMAIDANVLINERVREELRAGASPQAAIHTGY
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHCCH
ERAWATIFDSNITTLIAGVALLAFGSGPVRGFAVVHCLGILTSMFSAVLFSRGLVNLWYG
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
RRKKLKGVSIGQVWRPDGAVPPAAQA
CHHHCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]