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The map label for this gene is artQ [H]

Identifier: 124265325

GI number: 124265325

Start: 136099

End: 136851

Strand: Direct

Name: artQ [H]

Synonym: Mpe_A0132

Alternate gene names: 124265325

Gene position: 136099-136851 (Clockwise)

Preceding gene: 124265324

Following gene: 124265328

Centisome position: 3.37

GC content: 69.46

Gene sequence:

>753_bases
ATGGACTTTCGCTGGGAGATCCTGGCCGGCTACGGACCGCTGTTCCTGGCCGGCGTCCTGATGACGATCAAGCTGACGAT
CGTCGCGATCGTCGCCGGTCTCGCGCTCGGGCTGGTGCTGGGCCTGATCAGCAGCACGCGCTATGCGCCCAAGCCGAGGT
CGCCGCTGGGGGCGGCGCTGCTGAAGCCGGCGCAGTGGCTGACCATCGCCTACGTCACCTTCTTCCGCGGCACGCCGCTG
TTCGTGCAGATCCTGCTGGTGCACTTCGCGCTGATGCCGGCGCTGATCCACCCGGACAACGGCCTGCTGCTCACCGGCGA
GGCCGCGCGTGAGTTCCGCCAGAACTACGGCGCCTTCTTCTCCGGCGCGCTGGCGCTCACGCTGAACGCCGGCGCCTACA
TCTCCGAGATCTTCCGCGCCGGCATCCAGAGCATCCACGGCGGCCAGACGCAGGCGGCCTACAGCCTGGGCCTCACGCAC
GTGCAGAGCATGCGCCACGTGATCCTGCCGCAGGCCGTGCGCCGCATGGTGCCGCCGCTGGTCAACGAGGCGGTCACGCT
GATCAAGGATTCGTCGCTGGTGTCGGCGATCGGCCTGGCCGAGCTGGCGCTGGCCGCGCGCACCGTGGCCGGGGCCTACT
CGCGCTACTGGGAACCCTACCTCGCGATCTCGGCGGTCTACCTGCTGCTCACTTGGCTGCTGTCCACGCTGGCCAAGCGG
CTCGAATCGCCCGACCACCTGCGCGGGCGCTAG

Upstream 100 bases:

>100_bases
CGGCAGCTACGACCAGGTCTACGCCAAGACCTTCGGTGCAGCCGCTCCCGCGGCGGCGGCTTCCAAGTAAGCAGCGGCTT
CAGGACCCCGAGGATCTCCC

Downstream 100 bases:

>100_bases
ATCGCCAGCGGGTCCACGTCGACGGCCCAGCGCAACAGCCCCTTCTGCTCCGGCCGCTTGCGCCGCAGCGTGGCGTCCCA
GGCCGTGAGAAAGCGCTGCA

Product: amino acid ABC transporter

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MDFRWEILAGYGPLFLAGVLMTIKLTIVAIVAGLALGLVLGLISSTRYAPKPRSPLGAALLKPAQWLTIAYVTFFRGTPL
FVQILLVHFALMPALIHPDNGLLLTGEAAREFRQNYGAFFSGALALTLNAGAYISEIFRAGIQSIHGGQTQAAYSLGLTH
VQSMRHVILPQAVRRMVPPLVNEAVTLIKDSSLVSAIGLAELALAARTVAGAYSRYWEPYLAISAVYLLLTWLLSTLAKR
LESPDHLRGR

Sequences:

>Translated_250_residues
MDFRWEILAGYGPLFLAGVLMTIKLTIVAIVAGLALGLVLGLISSTRYAPKPRSPLGAALLKPAQWLTIAYVTFFRGTPL
FVQILLVHFALMPALIHPDNGLLLTGEAAREFRQNYGAFFSGALALTLNAGAYISEIFRAGIQSIHGGQTQAAYSLGLTH
VQSMRHVILPQAVRRMVPPLVNEAVTLIKDSSLVSAIGLAELALAARTVAGAYSRYWEPYLAISAVYLLLTWLLSTLAKR
LESPDHLRGR
>Mature_250_residues
MDFRWEILAGYGPLFLAGVLMTIKLTIVAIVAGLALGLVLGLISSTRYAPKPRSPLGAALLKPAQWLTIAYVTFFRGTPL
FVQILLVHFALMPALIHPDNGLLLTGEAAREFRQNYGAFFSGALALTLNAGAYISEIFRAGIQSIHGGQTQAAYSLGLTH
VQSMRHVILPQAVRRMVPPLVNEAVTLIKDSSLVSAIGLAELALAARTVAGAYSRYWEPYLAISAVYLLLTWLLSTLAKR
LESPDHLRGR

Specific function: Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=242, Percent_Identity=31.8181818181818, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788226, Length=238, Percent_Identity=34.0336134453782, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=35.5769230769231, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786874, Length=262, Percent_Identity=30.1526717557252, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787087, Length=231, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788645, Length=238, Percent_Identity=31.0924369747899, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994930, Length=117, Percent_Identity=40.1709401709402, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788646, Length=228, Percent_Identity=27.1929824561404, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787086, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082239, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27108; Mature: 27108

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRWEILAGYGPLFLAGVLMTIKLTIVAIVAGLALGLVLGLISSTRYAPKPRSPLGAAL
CCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LKPAQWLTIAYVTFFRGTPLFVQILLVHFALMPALIHPDNGLLLTGEAAREFRQNYGAFF
HCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHH
SGALALTLNAGAYISEIFRAGIQSIHGGQTQAAYSLGLTHVQSMRHVILPQAVRRMVPPL
HHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VNEAVTLIKDSSLVSAIGLAELALAARTVAGAYSRYWEPYLAISAVYLLLTWLLSTLAKR
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESPDHLRGR
CCCCCCCCCC
>Mature Secondary Structure
MDFRWEILAGYGPLFLAGVLMTIKLTIVAIVAGLALGLVLGLISSTRYAPKPRSPLGAAL
CCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
LKPAQWLTIAYVTFFRGTPLFVQILLVHFALMPALIHPDNGLLLTGEAAREFRQNYGAFF
HCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHH
SGALALTLNAGAYISEIFRAGIQSIHGGQTQAAYSLGLTHVQSMRHVILPQAVRRMVPPL
HHHHHEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VNEAVTLIKDSSLVSAIGLAELALAARTVAGAYSRYWEPYLAISAVYLLLTWLLSTLAKR
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESPDHLRGR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]