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The map label for this gene is creB [H]

Identifier: 124265328

GI number: 124265328

Start: 140497

End: 141252

Strand: Direct

Name: creB [H]

Synonym: Mpe_A0135

Alternate gene names: 124265328

Gene position: 140497-141252 (Clockwise)

Preceding gene: 124265325

Following gene: 124265329

Centisome position: 3.47

GC content: 72.88

Gene sequence:

>756_bases
ATGGCCCGCGCGCAGATCCTGATCGTCGAAGACGAACCCGGCATCGCCGACACGCTGAGCTACGCCCTGCGCACCGAAGG
CTTCGAGCCGCTGTGGTGCGCCACCGGCGAGGCGGCGCTGCAGCATCTGCCGCCGCAGGCGCCCGCCCCGGCGCTGGTGA
TCCTGGACGTGGGCCTGCCCGACCTCAACGGCTTCGAGCTCTTCAAGCGCATCCGCGAGCGCGCGGCCGATCTGCCCGTC
GTCTTCCTTACCGCGCGCAGCGACGAGATCGACCGCGTGGTGGGCCTGGAGCTCGGCGCCGACGACTACGTGGCCAAGCC
CTTCTCGCCGCGCGAGCTGGTGGCGCGCGTGCGCACCGTGCTGCGCCGCACGGCACGCGCCTCTGCTTCGCCGCCGCCCA
CCACCGTGGCCGGCGCCTTGACGCCGGCCGCTGCCGCGCTTCCAACCCCGATCGACGTGGACGAAGGCCGGCGCCGCATC
CGCTACTACGGCCGGCCGCTGGAGCTGTCGCGCTACGAGTACGGCCTGCTCAAGACCCTGGCCGAGCGCCCGGGCCACGT
GTACACCCGCGACGTGCTGCTGGAGCGGGTGTGGGACGACCCCGGCGACAGCTTCGACCGCACCGTGGACGCCCACGTGA
AGACTCTGCGCGCCAAGCTCAAGGCGGTGGCGCCCACGCTGGAGCCCATCCGCACGCACCGTGGCAGCGGCTACGCGCTG
GCCGAAGACCTGCCAGCCGAACTGCCGCGCGCATAG

Upstream 100 bases:

>100_bases
GGCAGGCGCGCAGGAAGCGGTCGTTCGCGAGCGGCGGCAGGGAGGCGGTGGGGGTGGCAGTCATCGGTCGATTATCGCGG
CCCTATCATCGGCGCCGACC

Downstream 100 bases:

>100_bases
ATCGGCCAGCCAGCCAGTGACGAAGCGCAACCGCATCTTCATCGGCATCCTGCTCGCCTATGCGCTGGGCGTGGCGCTGC
TGCTGTGGCGGCTGGTGGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MARAQILIVEDEPGIADTLSYALRTEGFEPLWCATGEAALQHLPPQAPAPALVILDVGLPDLNGFELFKRIRERAADLPV
VFLTARSDEIDRVVGLELGADDYVAKPFSPRELVARVRTVLRRTARASASPPPTTVAGALTPAAAALPTPIDVDEGRRRI
RYYGRPLELSRYEYGLLKTLAERPGHVYTRDVLLERVWDDPGDSFDRTVDAHVKTLRAKLKAVAPTLEPIRTHRGSGYAL
AEDLPAELPRA

Sequences:

>Translated_251_residues
MARAQILIVEDEPGIADTLSYALRTEGFEPLWCATGEAALQHLPPQAPAPALVILDVGLPDLNGFELFKRIRERAADLPV
VFLTARSDEIDRVVGLELGADDYVAKPFSPRELVARVRTVLRRTARASASPPPTTVAGALTPAAAALPTPIDVDEGRRRI
RYYGRPLELSRYEYGLLKTLAERPGHVYTRDVLLERVWDDPGDSFDRTVDAHVKTLRAKLKAVAPTLEPIRTHRGSGYAL
AEDLPAELPRA
>Mature_250_residues
ARAQILIVEDEPGIADTLSYALRTEGFEPLWCATGEAALQHLPPQAPAPALVILDVGLPDLNGFELFKRIRERAADLPVV
FLTARSDEIDRVVGLELGADDYVAKPFSPRELVARVRTVLRRTARASASPPPTTVAGALTPAAAALPTPIDVDEGRRRIR
YYGRPLELSRYEYGLLKTLAERPGHVYTRDVLLERVWDDPGDSFDRTVDAHVKTLRAKLKAVAPTLEPIRTHRGSGYALA
EDLPAELPRA

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=240, Percent_Identity=50.4166666666667, Blast_Score=227, Evalue=5e-61,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=40.5857740585774, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1786599, Length=245, Percent_Identity=37.9591836734694, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=35.5648535564854, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI2367329, Length=237, Percent_Identity=35.8649789029536, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1787229, Length=241, Percent_Identity=36.9294605809129, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=245, Percent_Identity=33.8775510204082, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786784, Length=238, Percent_Identity=35.2941176470588, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789809, Length=240, Percent_Identity=30.8333333333333, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.1888412017167, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789402, Length=241, Percent_Identity=35.2697095435685, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786911, Length=234, Percent_Identity=34.1880341880342, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082012, Length=237, Percent_Identity=32.4894514767932, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=192, Percent_Identity=31.7708333333333, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=35.5932203389831, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=178, Percent_Identity=30.8988764044944, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27586; Mature: 27455

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAQILIVEDEPGIADTLSYALRTEGFEPLWCATGEAALQHLPPQAPAPALVILDVGLP
CCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCCCEEEEEECCCC
DLNGFELFKRIRERAADLPVVFLTARSDEIDRVVGLELGADDYVAKPFSPRELVARVRTV
CCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
LRRTARASASPPPTTVAGALTPAAAALPTPIDVDEGRRRIRYYGRPLELSRYEYGLLKTL
HHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AERPGHVYTRDVLLERVWDDPGDSFDRTVDAHVKTLRAKLKAVAPTLEPIRTHRGSGYAL
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEH
AEDLPAELPRA
HHHCCCCCCCC
>Mature Secondary Structure 
ARAQILIVEDEPGIADTLSYALRTEGFEPLWCATGEAALQHLPPQAPAPALVILDVGLP
CCEEEEEEECCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHCCCCCCCCEEEEEECCCC
DLNGFELFKRIRERAADLPVVFLTARSDEIDRVVGLELGADDYVAKPFSPRELVARVRTV
CCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHEEEECCCCCCCCCCCHHHHHHHHHHH
LRRTARASASPPPTTVAGALTPAAAALPTPIDVDEGRRRIRYYGRPLELSRYEYGLLKTL
HHHHHHCCCCCCCCCHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AERPGHVYTRDVLLERVWDDPGDSFDRTVDAHVKTLRAKLKAVAPTLEPIRTHRGSGYAL
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEH
AEDLPAELPRA
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]