Click here to switch to the map view.

The map label for this gene is cysUT [H]

Identifier: 124265317

GI number: 124265317

Start: 126710

End: 127546

Strand: Direct

Name: cysUT [H]

Synonym: Mpe_A0124

Alternate gene names: 124265317

Gene position: 126710-127546 (Clockwise)

Preceding gene: 124265316

Following gene: 124265318

Centisome position: 3.13

GC content: 67.26

Gene sequence:

>837_bases
GTGTTCCTCTCTCGCGCCCTGCTGCGGCGACACAGCGTGCTGCCCGGCTTCGACCTCGCGCTCGGCTTCACGCTGCTCTA
CCTGAGCCTCATCGTGCTCATCCCGCTGTCGGCCGCGTTCCTGAAGACCTTCACGCTCACCTGGCCGGCGTTCTGGGAGG
CGGTGAGTTCGCCGCGGGTGGTGGCGTCCTACCGGCTGACCTTCGGCGCCTCACTGGCGGGTGCGCTGCTCAACGCGGTG
TTCGGGCTGGTCATCGCCTGGGTGCTGGTGCGCTACGAGTTCCCGTTCAAGCGCATCGTCGACGCGCTGGTCGACCTGCC
ATTCGCGCTGCCCACCGCGGTGGCCGGCATCGCGCTCACCGCGATCTATTCGCAGAACGGCTGGATCGGGCAGTACCTGC
CCTTCAAGGTGAGCTTCACGCCGGTCGGCGTGTTCGTCGCGCTCACCTTCATCGGCCTGCCGTTCGTCGTGCGCACGCTG
CAGCCGGTGCTCGAGGACCTGAGCAAGGAGATCGAGGAAGCGTCCGCCACCCTGGGCGCGAGCCGCGCACAGACCTTCCG
GCTCGTGATCTTCCCGATCCTGATCCCGGCACTGCTGACCGGCTTCGCGCTCGCCTTCGCACGCGCGCTGGGCGAGTACG
GCTCGGTGATCTTCATCGCCGGCAACCTGCCACTGGTCAGCGAGATCACGCCGCTGCTAATCATCACCAAGCTCGAGCAG
TACGACTACGCCGGCGCCACCGCGATCGCGGTCGTGATGCTGGTGTCGAGCTTCGTGCTGCTGCTGGGCATCAACCTGCT
GCAGGCCTGGTCGCGCCGTCGCCAGGGAGGAAACTGA

Upstream 100 bases:

>100_bases
GGCGCAGAAGGAGCACTTCGACGACGGCGGGATCTACGACCAGATCCTGGCGGCGCGCAAGTGATCGTGCCGGTTCGATC
ATTTTCCTGAAGTACTGACC

Downstream 100 bases:

>100_bases
CATGACGACCGGCGCCACGCTGGCCCTGAAGGCCGCTGCACCCGCTGCGGCGGTCGCTCCGACGAACCTGCGCAACGCCA
CCTCGGAGGCGCCCTGGGTG

Product: ABC type transporter

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MFLSRALLRRHSVLPGFDLALGFTLLYLSLIVLIPLSAAFLKTFTLTWPAFWEAVSSPRVVASYRLTFGASLAGALLNAV
FGLVIAWVLVRYEFPFKRIVDALVDLPFALPTAVAGIALTAIYSQNGWIGQYLPFKVSFTPVGVFVALTFIGLPFVVRTL
QPVLEDLSKEIEEASATLGASRAQTFRLVIFPILIPALLTGFALAFARALGEYGSVIFIAGNLPLVSEITPLLIITKLEQ
YDYAGATAIAVVMLVSSFVLLLGINLLQAWSRRRQGGN

Sequences:

>Translated_278_residues
MFLSRALLRRHSVLPGFDLALGFTLLYLSLIVLIPLSAAFLKTFTLTWPAFWEAVSSPRVVASYRLTFGASLAGALLNAV
FGLVIAWVLVRYEFPFKRIVDALVDLPFALPTAVAGIALTAIYSQNGWIGQYLPFKVSFTPVGVFVALTFIGLPFVVRTL
QPVLEDLSKEIEEASATLGASRAQTFRLVIFPILIPALLTGFALAFARALGEYGSVIFIAGNLPLVSEITPLLIITKLEQ
YDYAGATAIAVVMLVSSFVLLLGINLLQAWSRRRQGGN
>Mature_278_residues
MFLSRALLRRHSVLPGFDLALGFTLLYLSLIVLIPLSAAFLKTFTLTWPAFWEAVSSPRVVASYRLTFGASLAGALLNAV
FGLVIAWVLVRYEFPFKRIVDALVDLPFALPTAVAGIALTAIYSQNGWIGQYLPFKVSFTPVGVFVALTFIGLPFVVRTL
QPVLEDLSKEIEEASATLGASRAQTFRLVIFPILIPALLTGFALAFARALGEYGSVIFIAGNLPLVSEITPLLIITKLEQ
YDYAGATAIAVVMLVSSFVLLLGINLLQAWSRRRQGGN

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=271, Percent_Identity=49.4464944649446, Blast_Score=239, Evalue=1e-64,
Organism=Escherichia coli, GI87082099, Length=274, Percent_Identity=30.2919708029197, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786980, Length=201, Percent_Identity=31.8407960199005, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787369, Length=216, Percent_Identity=25.462962962963, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786254, Length=243, Percent_Identity=27.9835390946502, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30226; Mature: 30226

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSRALLRRHSVLPGFDLALGFTLLYLSLIVLIPLSAAFLKTFTLTWPAFWEAVSSPRV
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VASYRLTFGASLAGALLNAVFGLVIAWVLVRYEFPFKRIVDALVDLPFALPTAVAGIALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHH
AIYSQNGWIGQYLPFKVSFTPVGVFVALTFIGLPFVVRTLQPVLEDLSKEIEEASATLGA
HHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRAQTFRLVIFPILIPALLTGFALAFARALGEYGSVIFIAGNLPLVSEITPLLIITKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
YDYAGATAIAVVMLVSSFVLLLGINLLQAWSRRRQGGN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFLSRALLRRHSVLPGFDLALGFTLLYLSLIVLIPLSAAFLKTFTLTWPAFWEAVSSPRV
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VASYRLTFGASLAGALLNAVFGLVIAWVLVRYEFPFKRIVDALVDLPFALPTAVAGIALT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHH
AIYSQNGWIGQYLPFKVSFTPVGVFVALTFIGLPFVVRTLQPVLEDLSKEIEEASATLGA
HHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SRAQTFRLVIFPILIPALLTGFALAFARALGEYGSVIFIAGNLPLVSEITPLLIITKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
YDYAGATAIAVVMLVSSFVLLLGINLLQAWSRRRQGGN
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]