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The map label for this gene is wecB [C]

Identifier: 124025565

GI number: 124025565

Start: 787607

End: 788719

Strand: Reverse

Name: wecB [C]

Synonym: NATL1_08581

Alternate gene names: 124025565

Gene position: 788719-787607 (Counterclockwise)

Preceding gene: 124025566

Following gene: 124025559

Centisome position: 42.3

GC content: 31.81

Gene sequence:

>1113_bases
TTGAAACGTATATCAGTAATTATTGGAACAAGGCCTGAGGCTATAAAATTTGGTCCGTTAATTCTTGCTTTTCTAAAAAC
CAAAGAAATAGATTTAAGGATTATTTCAACAGGTCAACATTATGAACTAGTAGATCAAGTAAATGAATTGTTTAAAATTG
TGCCCAACAAGAACCTTAAGATTATGGTTCCTGGGCAAAGTCTTACAAAGATAACTAATGAAGTTTTAATAGGATTAAAA
GAAGACTTTAATGAATATCCACCCGATTTAGTATTAGTCCAAGGAGATACTACTTCAGCCTTTTCTGCTGCTCTGGCAGC
ATTTTATGAAAAAATTCCAATAGGGCATATTGAAGCTGGGTTAAGAACAAATCAAATTATGCTTCCATATCCTGAAGAAG
CGAATAGAAGAATTATTTCCCAAATAGCTTCTATTCATTTTGCTCCTACTAAAATTGCTTTTGAAAATCTAAAAAAAGAA
TCTGTACTTGGTGAAGTTTATTTAACAGGAAATACTGTTGTTGACAGCTTATTATTTATATCAGAAAAAGCACAAATCCC
AAAAATTAAAAATGTAGATTTTATAAAACAAAAAATCATATTAGCTACAGTTCACAGACGTGAAAACTGGGGGGCGAATT
TAAAACAAATAGCAAAGGGTTTAAAAAAGATTTTGGATGAACATCTCGATTATATTCTAATCCTTCCAATGCACCCAAAT
AAGTCACTTAGAGAACCATTAGAGGAAATACTTGGAGTGCATGAAAGAGCTATATTAACAGAATCGTTATCTTACAACTC
ACTAGTTGGAACACTTAAGCACACTAAATTATTATTAACTGACTCTGGAGGCCTACAAGAAGAAGCTCCCACATTTGGAG
TGCCTGTATTAGTCCTAAGAGATTCAACAGAACGGCCAGAAGCAATAAAAGCTGGAACTGCAAAAATTGTTGGATCAAAC
CCAAATAAGATTTTCAAAGAAGCTAATAATCTTTTAACTAACCAAAAAGAATATCAAAAGATGTCTAAAGCAATCAATCC
TTTTGGAGATGGTAAAGCAAGTGAAAGAATTGTAAAATATTGTATTGAATTTCTTGAAAGAAATAAGAAATAA

Upstream 100 bases:

>100_bases
ATTTAATTTAAAAAGTTTAAAATTAATAATATTATTATAATTAAAAATAATAATAGATACTATAATTTATTATAATATCT
ATTATTATTTTTAAAATTAG

Downstream 100 bases:

>100_bases
AAGGGCTATAATTCAGTCATAAAAATAGAAGACACTAAAAAAGCGGGTCTATCAAAATCCCGGCACGGCTCCCGCCATAT
ACATTCTGTATTGCATTTGT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKRISVIIGTRPEAIKFGPLILAFLKTKEIDLRIISTGQHYELVDQVNELFKIVPNKNLKIMVPGQSLTKITNEVLIGLK
EDFNEYPPDLVLVQGDTTSAFSAALAAFYEKIPIGHIEAGLRTNQIMLPYPEEANRRIISQIASIHFAPTKIAFENLKKE
SVLGEVYLTGNTVVDSLLFISEKAQIPKIKNVDFIKQKIILATVHRRENWGANLKQIAKGLKKILDEHLDYILILPMHPN
KSLREPLEEILGVHERAILTESLSYNSLVGTLKHTKLLLTDSGGLQEEAPTFGVPVLVLRDSTERPEAIKAGTAKIVGSN
PNKIFKEANNLLTNQKEYQKMSKAINPFGDGKASERIVKYCIEFLERNKK

Sequences:

>Translated_370_residues
MKRISVIIGTRPEAIKFGPLILAFLKTKEIDLRIISTGQHYELVDQVNELFKIVPNKNLKIMVPGQSLTKITNEVLIGLK
EDFNEYPPDLVLVQGDTTSAFSAALAAFYEKIPIGHIEAGLRTNQIMLPYPEEANRRIISQIASIHFAPTKIAFENLKKE
SVLGEVYLTGNTVVDSLLFISEKAQIPKIKNVDFIKQKIILATVHRRENWGANLKQIAKGLKKILDEHLDYILILPMHPN
KSLREPLEEILGVHERAILTESLSYNSLVGTLKHTKLLLTDSGGLQEEAPTFGVPVLVLRDSTERPEAIKAGTAKIVGSN
PNKIFKEANNLLTNQKEYQKMSKAINPFGDGKASERIVKYCIEFLERNKK
>Mature_370_residues
MKRISVIIGTRPEAIKFGPLILAFLKTKEIDLRIISTGQHYELVDQVNELFKIVPNKNLKIMVPGQSLTKITNEVLIGLK
EDFNEYPPDLVLVQGDTTSAFSAALAAFYEKIPIGHIEAGLRTNQIMLPYPEEANRRIISQIASIHFAPTKIAFENLKKE
SVLGEVYLTGNTVVDSLLFISEKAQIPKIKNVDFIKQKIILATVHRRENWGANLKQIAKGLKKILDEHLDYILILPMHPN
KSLREPLEEILGVHERAILTESLSYNSLVGTLKHTKLLLTDSGGLQEEAPTFGVPVLVLRDSTERPEAIKAGTAKIVGSN
PNKIFKEANNLLTNQKEYQKMSKAINPFGDGKASERIVKYCIEFLERNKK

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=366, Percent_Identity=45.9016393442623, Blast_Score=329, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41495; Mature: 41495

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISVIIGTRPEAIKFGPLILAFLKTKEIDLRIISTGQHYELVDQVNELFKIVPNKNLK
CCEEEEEECCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEE
IMVPGQSLTKITNEVLIGLKEDFNEYPPDLVLVQGDTTSAFSAALAAFYEKIPIGHIEAG
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHCC
LRTNQIMLPYPEEANRRIISQIASIHFAPTKIAFENLKKESVLGEVYLTGNTVVDSLLFI
CCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEECHHHHHHHHHH
SEKAQIPKIKNVDFIKQKIILATVHRRENWGANLKQIAKGLKKILDEHLDYILILPMHPN
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
KSLREPLEEILGVHERAILTESLSYNSLVGTLKHTKLLLTDSGGLQEEAPTFGVPVLVLR
HHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEEEEEE
DSTERPEAIKAGTAKIVGSNPNKIFKEANNLLTNQKEYQKMSKAINPFGDGKASERIVKY
CCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
CIEFLERNKK
HHHHHHCCCC
>Mature Secondary Structure
MKRISVIIGTRPEAIKFGPLILAFLKTKEIDLRIISTGQHYELVDQVNELFKIVPNKNLK
CCEEEEEECCCCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEE
IMVPGQSLTKITNEVLIGLKEDFNEYPPDLVLVQGDTTSAFSAALAAFYEKIPIGHIEAG
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHCC
LRTNQIMLPYPEEANRRIISQIASIHFAPTKIAFENLKKESVLGEVYLTGNTVVDSLLFI
CCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEECHHHHHHHHHH
SEKAQIPKIKNVDFIKQKIILATVHRRENWGANLKQIAKGLKKILDEHLDYILILPMHPN
HCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCC
KSLREPLEEILGVHERAILTESLSYNSLVGTLKHTKLLLTDSGGLQEEAPTFGVPVLVLR
HHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEEEEEE
DSTERPEAIKAGTAKIVGSNPNKIFKEANNLLTNQKEYQKMSKAINPFGDGKASERIVKY
CCCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
CIEFLERNKK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]