Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 124025282

GI number: 124025282

Start: 516035

End: 516727

Strand: Direct

Name: lepB [H]

Synonym: NATL1_05711

Alternate gene names: 124025282

Gene position: 516035-516727 (Clockwise)

Preceding gene: 124025281

Following gene: 124025284

Centisome position: 27.67

GC content: 37.81

Gene sequence:

>693_bases
GTGAAGCAAAATTATTCAGATTCGACTAAAGAAGCTAAAAATTGTTGGTGGTATTCTTTTTTTGATACGTGGGGACCTAT
CTCTCTAACTATTCTCCTTTATGTAGGTATTCGTCATTTTATCGCAGAAGCTAGATATATACCCTCGGGCTCAATGCTGC
CAGGATTGAAAATAAATGATCGACTAATTGTTGAAAAACTTTCTTTGCGCAAAAGGAAACCTTCGCGTGGGGAAATTGTT
GTTTTCAACTCACCATATTCCTTTGATCAGCAATTGATAGCTGATAGGACTAAACAACTTCCGTCTAAATTTCAATGTTC
ATTAATAACTTTTCCATTAATTTCTTGGATACCTGCTCTATCTGATCGTGCTTGTGATGCTTATATCAAACGAATAGTAG
CGGTTGGAGGAGATCGTCTTTTGATTAACGGCAAGGGAGAGATTAATTTGAATGGTAGATCAATCAATGAACCATATGTT
ATGAACTTCTGCCCAAGTAAACCTAAATTTAATCTATGTCCTCCGATGACTTCAACTGTTCCTAAGGGACATGTATTCGT
TTTGGGGGATAACCGTGCTAATAGTTGGGATAGTCGCTTTTGGCCAGGAGGGGGTTTCTTACCCCATAAAGAAATAATTG
GCAAAGCAAGCTGGCGCTTTTGGCCTATTAATCGTTTTGGTAAGCTTAATTAA

Upstream 100 bases:

>100_bases
GCTGAGAAATTACTTTGAAATTCACATGATCACTATCATTGACTGAATATGAGTAGTTTTTACAAATAAAGTAGACTATA
TATTTATTATTGATAATCAA

Downstream 100 bases:

>100_bases
TTAGCCCACAATCAATAACTTCCCAACTATTTTTTGGTCTTTGATCACACCTTTTTTGATTAAAACAGTTTTTCTCTTTA
TATATGATCCTGCCTTTTTA

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKQNYSDSTKEAKNCWWYSFFDTWGPISLTILLYVGIRHFIAEARYIPSGSMLPGLKINDRLIVEKLSLRKRKPSRGEIV
VFNSPYSFDQQLIADRTKQLPSKFQCSLITFPLISWIPALSDRACDAYIKRIVAVGGDRLLINGKGEINLNGRSINEPYV
MNFCPSKPKFNLCPPMTSTVPKGHVFVLGDNRANSWDSRFWPGGGFLPHKEIIGKASWRFWPINRFGKLN

Sequences:

>Translated_230_residues
MKQNYSDSTKEAKNCWWYSFFDTWGPISLTILLYVGIRHFIAEARYIPSGSMLPGLKINDRLIVEKLSLRKRKPSRGEIV
VFNSPYSFDQQLIADRTKQLPSKFQCSLITFPLISWIPALSDRACDAYIKRIVAVGGDRLLINGKGEINLNGRSINEPYV
MNFCPSKPKFNLCPPMTSTVPKGHVFVLGDNRANSWDSRFWPGGGFLPHKEIIGKASWRFWPINRFGKLN
>Mature_230_residues
MKQNYSDSTKEAKNCWWYSFFDTWGPISLTILLYVGIRHFIAEARYIPSGSMLPGLKINDRLIVEKLSLRKRKPSRGEIV
VFNSPYSFDQQLIADRTKQLPSKFQCSLITFPLISWIPALSDRACDAYIKRIVAVGGDRLLINGKGEINLNGRSINEPYV
MNFCPSKPKFNLCPPMTSTVPKGHVFVLGDNRANSWDSRFWPGGGFLPHKEIIGKASWRFWPINRFGKLN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 26276; Mature: 26276

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNYSDSTKEAKNCWWYSFFDTWGPISLTILLYVGIRHFIAEARYIPSGSMLPGLKIND
CCCCCCCCHHHHHHCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RLIVEKLSLRKRKPSRGEIVVFNSPYSFDQQLIADRTKQLPSKFQCSLITFPLISWIPAL
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SDRACDAYIKRIVAVGGDRLLINGKGEINLNGRSINEPYVMNFCPSKPKFNLCPPMTSTV
CCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCC
PKGHVFVLGDNRANSWDSRFWPGGGFLPHKEIIGKASWRFWPINRFGKLN
CCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MKQNYSDSTKEAKNCWWYSFFDTWGPISLTILLYVGIRHFIAEARYIPSGSMLPGLKIND
CCCCCCCCHHHHHHCEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RLIVEKLSLRKRKPSRGEIVVFNSPYSFDQQLIADRTKQLPSKFQCSLITFPLISWIPAL
HHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SDRACDAYIKRIVAVGGDRLLINGKGEINLNGRSINEPYVMNFCPSKPKFNLCPPMTSTV
CCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCC
PKGHVFVLGDNRANSWDSRFWPGGGFLPHKEIIGKASWRFWPINRFGKLN
CCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]