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The map label for this gene is glmS [H]

Identifier: 124027838

GI number: 124027838

Start: 975286

End: 977127

Strand: Reverse

Name: glmS [H]

Synonym: Hbut_0965

Alternate gene names: 124027838

Gene position: 977127-975286 (Counterclockwise)

Preceding gene: 124027839

Following gene: 124027837

Centisome position: 58.61

GC content: 48.7

Gene sequence:

>1842_bases
GTGTGTGGAATCGTTGGTATCACAGCTGACGGAGAGATTGTTGGAAGCATAACCAGGATGCTTGTTGATGGTCTAAAGAG
GCTAGAGTATAGGGGCTACGATAGCGCCGGCTTTGCACTTATAGAGTGTGGGACGGCTAGAATACTTGTCTTCAAGGATA
AAGGCAGAATCAGCCACGTGGTCGAAAAGTATGGTATTGAAGCCTACTGCTCCCATACAGGTATAGCGCATACACGCTGG
GCAACCCATGGCGAGCCTAGCCAGCGAAATGCGCATCCACACATAGACTGTAGGAGTGAAATAGCAGTCGTACACAATGG
AATTATTAAGAACTTTGCAGAGCTGCGCGAGTTGCTCGCTTCAAAGGGCCACATGTTCAGAAGCGATACCGATACCGAGG
TTATCGCCCACCTATTCGAGGAGTATGTCTCGAAAGGACTTGACGGACTAGAAGCCCTACGCAAGATAGTTCAGGTACTC
GAAGGAGCATATGCTATAGCCATCATAAACGCACGTGAACCTTTAAGGATATACTTTGCGCGAAGAGTCAGCCCCCTCAT
TATAGGGCTTGGCGAAGGCTTCAACATGGTGTCTAGCGACATACCCTCCATACTACCATATACACGCCGAGTAATAGTAC
TCGAGGACGGAGAGTACGGGTTCATAGAACCCTACAAGGTGTACATCGAGAAGGACGGGAAACCAATCAACTGGAGGACA
CGAGTGATACGGGTTGAGTGGAGTATTGAGGATGCAGAGAAGGGCGGCTATCCCCACTACATGTTAAAGGAGATTATGGA
GCAACCTAGGGTTCTCTACGAGACATACACAGGACTTCTCTCCTCAAAAGAGCTGGCTGAGGCTGCAAAGCTGATAGCAT
CGGCTAGAAAAGTGTTTATCACAGGTGCAGGAACAAGTTATCATGCAGGCCTAGTTTTTGCCTACTACATAGCAAGGTAT
GCTAAGAGAGTAGCTACGCCGTTTATAGCGAGTGAATACACCGTTTACTCCGATGTAGCAGATGAGGATTCCGTGCTTAT
AGCTGTTAGTCAGAGCGGCGAAACCATAGATACCCTGCAAGCTCTGAGAGCCTTCAAGTCTAAAGGCGCAAAAATCATAG
CCGTATCCAATGTTCTCGGAAGCACTATACCACGAGAGTCACATACAACAATCTATACTAGGGCAGGCCCCGAGATAGGT
GTCGCAGCAACGAAAACCTTCCTCACGCAAGTCCTGGCACTAACATCGCTTGCACTAACACTCGCAACCGAGGAGGGTAC
TATTACAACTACGGAGTATAAGAAAGCTATTGAAGAACTAGCCCTGGCTGGCAGGGCTGCTGCAAGAAGTATAGATGCAA
GCCTACGCATACTGGATAAACTCGTCCTGGTACTAAAGAATAAGGGCAACATGTACATCCTAAGTCGTGGCATCGGTGTA
CCCCTAGCTTATGAAGCTGCTCTAAAAGTCAAGGAGGTAAGCTACATACATGCAGAAGCCTATCCAGCCGGAGAGAGCAA
GCACGGCCCAATAGCACTTGTCGAGAGGGACTTCCCAGTCATATTCCTCGGTGTGCCACCCGAGGATGTGTTACTTGAAA
AGCTGCAAGGCAACGTTATGGAGATGAAAGCAAGAGGTGCCCACACAATCGTTATTGGCACAACACCCTATGGTAAGCTA
GAAGGCGTAGACGTCTTCATAGATGTTGGCAGCTACGATGAACTCCTCATACCCTATGCTATAATACCGCCAGCACAGCT
GCTAGCCTACAAGTTGGCTGTAGCCCTAAACCGTGACCCCGATAAGCCGCGTAACCTCGCAAAGACTGTTACAGTCGAGT
AA

Upstream 100 bases:

>100_bases
TTATACCCTCTCAATTCTATGTCTTTCGCGAAGAGTGTGCACCCAGACAGTCCTGTAGCGTAGAAGACTAGAAGATTGAA
GCCTGGAGGGGCTATGGACC

Downstream 100 bases:

>100_bases
CTGTGTGGTGGCGTGAACCTTGAAGGCGATCATACTTGCAGGTGGCCCCCCAAAGAAGCTACGCTACGTGGTGACTAGTA
CTAGGTCTAGAGCGCTCCTA

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MCGIVGITADGEIVGSITRMLVDGLKRLEYRGYDSAGFALIECGTARILVFKDKGRISHVVEKYGIEAYCSHTGIAHTRW
ATHGEPSQRNAHPHIDCRSEIAVVHNGIIKNFAELRELLASKGHMFRSDTDTEVIAHLFEEYVSKGLDGLEALRKIVQVL
EGAYAIAIINAREPLRIYFARRVSPLIIGLGEGFNMVSSDIPSILPYTRRVIVLEDGEYGFIEPYKVYIEKDGKPINWRT
RVIRVEWSIEDAEKGGYPHYMLKEIMEQPRVLYETYTGLLSSKELAEAAKLIASARKVFITGAGTSYHAGLVFAYYIARY
AKRVATPFIASEYTVYSDVADEDSVLIAVSQSGETIDTLQALRAFKSKGAKIIAVSNVLGSTIPRESHTTIYTRAGPEIG
VAATKTFLTQVLALTSLALTLATEEGTITTTEYKKAIEELALAGRAAARSIDASLRILDKLVLVLKNKGNMYILSRGIGV
PLAYEAALKVKEVSYIHAEAYPAGESKHGPIALVERDFPVIFLGVPPEDVLLEKLQGNVMEMKARGAHTIVIGTTPYGKL
EGVDVFIDVGSYDELLIPYAIIPPAQLLAYKLAVALNRDPDKPRNLAKTVTVE

Sequences:

>Translated_613_residues
MCGIVGITADGEIVGSITRMLVDGLKRLEYRGYDSAGFALIECGTARILVFKDKGRISHVVEKYGIEAYCSHTGIAHTRW
ATHGEPSQRNAHPHIDCRSEIAVVHNGIIKNFAELRELLASKGHMFRSDTDTEVIAHLFEEYVSKGLDGLEALRKIVQVL
EGAYAIAIINAREPLRIYFARRVSPLIIGLGEGFNMVSSDIPSILPYTRRVIVLEDGEYGFIEPYKVYIEKDGKPINWRT
RVIRVEWSIEDAEKGGYPHYMLKEIMEQPRVLYETYTGLLSSKELAEAAKLIASARKVFITGAGTSYHAGLVFAYYIARY
AKRVATPFIASEYTVYSDVADEDSVLIAVSQSGETIDTLQALRAFKSKGAKIIAVSNVLGSTIPRESHTTIYTRAGPEIG
VAATKTFLTQVLALTSLALTLATEEGTITTTEYKKAIEELALAGRAAARSIDASLRILDKLVLVLKNKGNMYILSRGIGV
PLAYEAALKVKEVSYIHAEAYPAGESKHGPIALVERDFPVIFLGVPPEDVLLEKLQGNVMEMKARGAHTIVIGTTPYGKL
EGVDVFIDVGSYDELLIPYAIIPPAQLLAYKLAVALNRDPDKPRNLAKTVTVE
>Mature_613_residues
MCGIVGITADGEIVGSITRMLVDGLKRLEYRGYDSAGFALIECGTARILVFKDKGRISHVVEKYGIEAYCSHTGIAHTRW
ATHGEPSQRNAHPHIDCRSEIAVVHNGIIKNFAELRELLASKGHMFRSDTDTEVIAHLFEEYVSKGLDGLEALRKIVQVL
EGAYAIAIINAREPLRIYFARRVSPLIIGLGEGFNMVSSDIPSILPYTRRVIVLEDGEYGFIEPYKVYIEKDGKPINWRT
RVIRVEWSIEDAEKGGYPHYMLKEIMEQPRVLYETYTGLLSSKELAEAAKLIASARKVFITGAGTSYHAGLVFAYYIARY
AKRVATPFIASEYTVYSDVADEDSVLIAVSQSGETIDTLQALRAFKSKGAKIIAVSNVLGSTIPRESHTTIYTRAGPEIG
VAATKTFLTQVLALTSLALTLATEEGTITTTEYKKAIEELALAGRAAARSIDASLRILDKLVLVLKNKGNMYILSRGIGV
PLAYEAALKVKEVSYIHAEAYPAGESKHGPIALVERDFPVIFLGVPPEDVLLEKLQGNVMEMKARGAHTIVIGTTPYGKL
EGVDVFIDVGSYDELLIPYAIIPPAQLLAYKLAVALNRDPDKPRNLAKTVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=680, Percent_Identity=32.0588235294118, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI205277386, Length=672, Percent_Identity=32.1428571428571, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI29570798, Length=146, Percent_Identity=32.1917808219178, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790167, Length=622, Percent_Identity=40.6752411575563, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788651, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532899, Length=437, Percent_Identity=33.1807780320366, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532897, Length=437, Percent_Identity=33.1807780320366, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17539970, Length=438, Percent_Identity=32.648401826484, Blast_Score=204, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6322745, Length=433, Percent_Identity=32.7944572748268, Blast_Score=203, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6323731, Length=427, Percent_Identity=26.463700234192, Blast_Score=131, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=38.5365853658537, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6323958, Length=205, Percent_Identity=28.2926829268293, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357745, Length=710, Percent_Identity=31.6901408450704, Blast_Score=304, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67339; Mature: 67339

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGITADGEIVGSITRMLVDGLKRLEYRGYDSAGFALIECGTARILVFKDKGRISHV
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCCHHHHH
VEKYGIEAYCSHTGIAHTRWATHGEPSQRNAHPHIDCRSEIAVVHNGIIKNFAELRELLA
HHHHCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SKGHMFRSDTDTEVIAHLFEEYVSKGLDGLEALRKIVQVLEGAYAIAIINAREPLRIYFA
CCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHH
RRVSPLIIGLGEGFNMVSSDIPSILPYTRRVIVLEDGEYGFIEPYKVYIEKDGKPINWRT
HCCCEEEEECCCCCCHHHHCCCHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEE
RVIRVEWSIEDAEKGGYPHYMLKEIMEQPRVLYETYTGLLSSKELAEAAKLIASARKVFI
EEEEEEEEEEHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEE
TGAGTSYHAGLVFAYYIARYAKRVATPFIASEYTVYSDVADEDSVLIAVSQSGETIDTLQ
EECCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCEEEEECCCCCHHHHHH
ALRAFKSKGAKIIAVSNVLGSTIPRESHTTIYTRAGPEIGVAATKTFLTQVLALTSLALT
HHHHHHHCCCEEEEEEHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHE
LATEEGTITTTEYKKAIEELALAGRAAARSIDASLRILDKLVLVLKNKGNMYILSRGIGV
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
PLAYEAALKVKEVSYIHAEAYPAGESKHGPIALVERDFPVIFLGVPPEDVLLEKLQGNVM
CEEHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHCCCCE
EMKARGAHTIVIGTTPYGKLEGVDVFIDVGSYDELLIPYAIIPPAQLLAYKLAVALNRDP
EEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCEEECEEECCHHHHHHHHHHHHCCCCC
DKPRNLAKTVTVE
CCCHHHCCEEECC
>Mature Secondary Structure
MCGIVGITADGEIVGSITRMLVDGLKRLEYRGYDSAGFALIECGTARILVFKDKGRISHV
CCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCCHHHHH
VEKYGIEAYCSHTGIAHTRWATHGEPSQRNAHPHIDCRSEIAVVHNGIIKNFAELRELLA
HHHHCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SKGHMFRSDTDTEVIAHLFEEYVSKGLDGLEALRKIVQVLEGAYAIAIINAREPLRIYFA
CCCCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHH
RRVSPLIIGLGEGFNMVSSDIPSILPYTRRVIVLEDGEYGFIEPYKVYIEKDGKPINWRT
HCCCEEEEECCCCCCHHHHCCCHHCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCEEE
RVIRVEWSIEDAEKGGYPHYMLKEIMEQPRVLYETYTGLLSSKELAEAAKLIASARKVFI
EEEEEEEEEEHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEE
TGAGTSYHAGLVFAYYIARYAKRVATPFIASEYTVYSDVADEDSVLIAVSQSGETIDTLQ
EECCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCCCEEEEECCCCCHHHHHH
ALRAFKSKGAKIIAVSNVLGSTIPRESHTTIYTRAGPEIGVAATKTFLTQVLALTSLALT
HHHHHHHCCCEEEEEEHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHE
LATEEGTITTTEYKKAIEELALAGRAAARSIDASLRILDKLVLVLKNKGNMYILSRGIGV
EEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
PLAYEAALKVKEVSYIHAEAYPAGESKHGPIALVERDFPVIFLGVPPEDVLLEKLQGNVM
CEEHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHCCCCE
EMKARGAHTIVIGTTPYGKLEGVDVFIDVGSYDELLIPYAIIPPAQLLAYKLAVALNRDP
EEECCCCEEEEEECCCCCCCCCEEEEEECCCCCCEEECEEECCHHHHHHHHHHHHCCCCC
DKPRNLAKTVTVE
CCCHHHCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]