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The map label for this gene is glmU [H]

Identifier: 124027837

GI number: 124027837

Start: 974127

End: 975266

Strand: Reverse

Name: glmU [H]

Synonym: Hbut_0964

Alternate gene names: 124027837

Gene position: 975266-974127 (Counterclockwise)

Preceding gene: 124027838

Following gene: 124027836

Centisome position: 58.5

GC content: 48.6

Gene sequence:

>1140_bases
TTGAAGGCGATCATACTTGCAGGTGGCCCCCCAAAGAAGCTACGCTACGTGGTGACTAGTACTAGGTCTAGAGCGCTCCT
ACGCTTCCCGGGAGGCGTACTCCTTGAGTTCCATTTACGCGCAGCAAGAAGGTATTTTGATACTATAGTAGTGGTCTCTG
ACGACCCAAACGTGTACAAGTACTGTAGCATGAAGGGATGTAACTTTGTCCCCCAGAGATCGCCGGGCATAGAGGGAGCT
ATATGTGATGGCTTATCCGGACTTAGTGTTCATGGAGAGGACCTTGTAACGCTAATCTACTCCGACATATACTTTGGCGA
AGGGTTTATCGACACCCACATGAATGCCCTTCTGAGGAGCTATGAGCCCTTGATAACCGTTACTAAACCCGTAATAATGC
GTGAAACCTTTCTACGCATAGATGCCGACCCGATAAGCCAGCAGGTAAATGCCATCGGACAAGGGGGCCTCATATTTGCT
GGGCTAGCCTCCCTTCCTGCCAAGGAGCTTCACGAACTAGTGTGTCGTGGCGGAAAACCACTTCCCGACGTACTCCGCCA
CCTTGCACATACCGGTAGACTTAATGCGAATCACTGGATTGGAGAGTGGGTGGATATAGATACACCATGGGACTATCTTC
TTGCAACAAGGCTAGCTCTAGCCAGACACAAGGGGATCTATATACATGATGAGGCCATTGTGAAGGAGACTAGCGTTCTA
GAACCACCAGTTTACATTGATACAAAAGCCTTCATAGATCACTATGCAGTCATCAAGGGACCTGTCTATATCGGTGTAGG
TGCCCGCATAGGGGCACACAGCTTCGTCCGGAACTATACTGCAATATATTCAAACGCGCTTGTTGGCGCATACACAGAGG
TTAAACGTAGTATAGTATACGACTCTGCAAGTATCTCCTCGCACTGTTATGTAGCTGACAGTATTATCGGCGAGGAGGCT
AGTCTAGCACCCTATACAATAACCCTAAACACACCTATAGAGATGGTTAGCAATGAGATAATACTAACAACGTCTTATCC
GCTCGAGAGGGTTAAGGTTGGTGCCGTAATCGCTGCAAGAGCAGAGACTAAGCCGCACCAGGTTCTGAATCCCGCAGAGA
TCTACGAAGGCAGTGAATAG

Upstream 100 bases:

>100_bases
CTAGCCTACAAGTTGGCTGTAGCCCTAAACCGTGACCCCGATAAGCCGCGTAACCTCGCAAAGACTGTTACAGTCGAGTA
ACTGTGTGGTGGCGTGAACC

Downstream 100 bases:

>100_bases
CGGGGCTCAGCGCTTTGGCCCCTCCACATACGCATCTTATTTTCGGCTGCCCGGCTCTAGCATATAAGCCGGGGGCAGGA
TCCTTCATAGCCCCCAGCAT

Product: glucose-1-phosphate thymidylyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKAIILAGGPPKKLRYVVTSTRSRALLRFPGGVLLEFHLRAARRYFDTIVVVSDDPNVYKYCSMKGCNFVPQRSPGIEGA
ICDGLSGLSVHGEDLVTLIYSDIYFGEGFIDTHMNALLRSYEPLITVTKPVIMRETFLRIDADPISQQVNAIGQGGLIFA
GLASLPAKELHELVCRGGKPLPDVLRHLAHTGRLNANHWIGEWVDIDTPWDYLLATRLALARHKGIYIHDEAIVKETSVL
EPPVYIDTKAFIDHYAVIKGPVYIGVGARIGAHSFVRNYTAIYSNALVGAYTEVKRSIVYDSASISSHCYVADSIIGEEA
SLAPYTITLNTPIEMVSNEIILTTSYPLERVKVGAVIAARAETKPHQVLNPAEIYEGSE

Sequences:

>Translated_379_residues
MKAIILAGGPPKKLRYVVTSTRSRALLRFPGGVLLEFHLRAARRYFDTIVVVSDDPNVYKYCSMKGCNFVPQRSPGIEGA
ICDGLSGLSVHGEDLVTLIYSDIYFGEGFIDTHMNALLRSYEPLITVTKPVIMRETFLRIDADPISQQVNAIGQGGLIFA
GLASLPAKELHELVCRGGKPLPDVLRHLAHTGRLNANHWIGEWVDIDTPWDYLLATRLALARHKGIYIHDEAIVKETSVL
EPPVYIDTKAFIDHYAVIKGPVYIGVGARIGAHSFVRNYTAIYSNALVGAYTEVKRSIVYDSASISSHCYVADSIIGEEA
SLAPYTITLNTPIEMVSNEIILTTSYPLERVKVGAVIAARAETKPHQVLNPAEIYEGSE
>Mature_379_residues
MKAIILAGGPPKKLRYVVTSTRSRALLRFPGGVLLEFHLRAARRYFDTIVVVSDDPNVYKYCSMKGCNFVPQRSPGIEGA
ICDGLSGLSVHGEDLVTLIYSDIYFGEGFIDTHMNALLRSYEPLITVTKPVIMRETFLRIDADPISQQVNAIGQGGLIFA
GLASLPAKELHELVCRGGKPLPDVLRHLAHTGRLNANHWIGEWVDIDTPWDYLLATRLALARHKGIYIHDEAIVKETSVL
EPPVYIDTKAFIDHYAVIKGPVYIGVGARIGAHSFVRNYTAIYSNALVGAYTEVKRSIVYDSASISSHCYVADSIIGEEA
SLAPYTITLNTPIEMVSNEIILTTSYPLERVKVGAVIAARAETKPHQVLNPAEIYEGSE

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 41695; Mature: 41695

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIILAGGPPKKLRYVVTSTRSRALLRFPGGVLLEFHLRAARRYFDTIVVVSDDPNVYK
CEEEEECCCCCHHEEEEEECCCCCEEEECCCCEEEHHHHHHHHHHHEEEEEECCCCCEEE
YCSMKGCNFVPQRSPGIEGAICDGLSGLSVHGEDLVTLIYSDIYFGEGFIDTHMNALLRS
EECCCCCCCCCCCCCCCCCHHHCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
YEPLITVTKPVIMRETFLRIDADPISQQVNAIGQGGLIFAGLASLPAKELHELVCRGGKP
CCCEEEECCHHHHHHHHHEECCCHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHCCCCC
LPDVLRHLAHTGRLNANHWIGEWVDIDTPWDYLLATRLALARHKGIYIHDEAIVKETSVL
HHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHCC
EPPVYIDTKAFIDHYAVIKGPVYIGVGARIGAHSFVRNYTAIYSNALVGAYTEVKRSIVY
CCCEEEEHHHHHHHHHEEECCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
DSASISSHCYVADSIIGEEASLAPYTITLNTPIEMVSNEIILTTSYPLERVKVGAVIAAR
CCCCCCCCEEEEHHHCCCCCCCCCEEEEECCCHHHHCCCEEEEECCCHHHEEECEEEEEC
AETKPHQVLNPAEIYEGSE
CCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MKAIILAGGPPKKLRYVVTSTRSRALLRFPGGVLLEFHLRAARRYFDTIVVVSDDPNVYK
CEEEEECCCCCHHEEEEEECCCCCEEEECCCCEEEHHHHHHHHHHHEEEEEECCCCCEEE
YCSMKGCNFVPQRSPGIEGAICDGLSGLSVHGEDLVTLIYSDIYFGEGFIDTHMNALLRS
EECCCCCCCCCCCCCCCCCHHHCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
YEPLITVTKPVIMRETFLRIDADPISQQVNAIGQGGLIFAGLASLPAKELHELVCRGGKP
CCCEEEECCHHHHHHHHHEECCCHHHHHHHHCCCCCEEEEEHHHCCHHHHHHHHHCCCCC
LPDVLRHLAHTGRLNANHWIGEWVDIDTPWDYLLATRLALARHKGIYIHDEAIVKETSVL
HHHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHCC
EPPVYIDTKAFIDHYAVIKGPVYIGVGARIGAHSFVRNYTAIYSNALVGAYTEVKRSIVY
CCCEEEEHHHHHHHHHEEECCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
DSASISSHCYVADSIIGEEASLAPYTITLNTPIEMVSNEIILTTSYPLERVKVGAVIAAR
CCCCCCCCEEEEHHHCCCCCCCCCEEEEECCCHHHHCCCEEEEECCCHHHEEECEEEEEC
AETKPHQVLNPAEIYEGSE
CCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]