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The map label for this gene is thrC [H]

Identifier: 124027647

GI number: 124027647

Start: 762230

End: 763330

Strand: Reverse

Name: thrC [H]

Synonym: Hbut_0768

Alternate gene names: 124027647

Gene position: 763330-762230 (Counterclockwise)

Preceding gene: 124027648

Following gene: 124027644

Centisome position: 45.79

GC content: 61.67

Gene sequence:

>1101_bases
TTGGCTGGTAGCGCTGAATGGATTTGTCCTCGATGTGGGTGGAGTGCGGCTATAGGCTCCGGCTACTACTGGCGCTGCCC
CCGTTGTAGCGGGCCTCTGCAGCTCCGGTATACGCGGCGCTGGGAGCCCCGCAGCGGCTGCAGCGGCCTTGCGAAGTATT
CTTCGATGCTCCCCTTGGAGGTTCCCCGCGTTCTCGGGGAGGGTGGCACGCCGCTCGTTGAACGCCGCGTTGAGGGGGTT
AGGGTGTTCTTCAAGCTCGAGTATCTGAACCCTACCGGGAGCTTTAAGGACCGTGGAACCAGCCTTGCTTTAGCCTATGC
TTCCCGCATGGGGTTCAGGCTGGTTGTAGAGGATACTTCGGGCAATACCGGGATCTCAGTAGCCGCGTACGCTGCCGCCT
ACGGGCTCCGTGCAAGGATATACATGCCTGTCAATGCTCCGGAGGGAAAGAAGAGGCTTGTAAGAGCCCTCGGCGGGGAG
GTGGTCCTGACTCCTAGTCGTGGCGAGGCTGCCCAGGCCGTACTATGGGAGCTCAAGAAGCCTGACGTGTTCTATGTGGC
TCACACCTGGAGCCCATTCTACGTCGAGGGCGCGAAAACAATAGCCTTCGAGGCCTTCGAGGACGGGTTCCGTGGGTCAG
CCGTGCTTGTACCTGTGGGTTCTGGCGGGCTCCTCCTCGGGATCTACCATGGCTTCCGTGAGCTTGTCGAGCAAGGCCTC
ATAGACAGCGTGCCCAGGATCATCGCGGTGCAGGGCTACTCCAACCCGCCCCTCTACCGGGCAGTCTACGGTAAGGAGCC
CGAAGCCGAGGAACGCAGCTCGAGGCTAGCCGACGGCCTAATGGTGTCGGAGCCGCCCCGGCTCGGTGAGGCTGCTGAAG
CCGTAAAGGCCACGGGGGGCTGCGTGATACTCGTCGACGACGAGGGGATTAGGAGGGGGCTGAAGATGTTGGCGTCGATG
GGCTTCATAGTCGAGCCCACGAGTGCGACGCTATATCCGGCCCTCCTGGAGGCTGTTGAGAGGGGCTGCATAGACAAGGG
CGAGGAGGTGCTGGCACCACTCACTGGGTCGGGGCTAAAAACACTCGAGTACTTCAAGTAG

Upstream 100 bases:

>100_bases
ATATCGTTGTGTTGTAGAGTATTCCTAGCCCCTCTTTCTGGAGAGGTATTCAGCTTTAGGGGACTGCGTGTACGTTGTCT
TCCCGGGGGCTTAGTCTGTC

Downstream 100 bases:

>100_bases
CCCCATCACTCCACATCCTACGGGGCTATATCAGGCTCCCAGAGAATCTCCACAGCCTTACCCGGCACCACTGTTTCCAG
GTATGCTCGGCGTAGCCTCG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAGSAEWICPRCGWSAAIGSGYYWRCPRCSGPLQLRYTRRWEPRSGCSGLAKYSSMLPLEVPRVLGEGGTPLVERRVEGV
RVFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDTSGNTGISVAAYAAAYGLRARIYMPVNAPEGKKRLVRALGGE
VVLTPSRGEAAQAVLWELKKPDVFYVAHTWSPFYVEGAKTIAFEAFEDGFRGSAVLVPVGSGGLLLGIYHGFRELVEQGL
IDSVPRIIAVQGYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEPPRLGEAAEAVKATGGCVILVDDEGIRRGLKMLASM
GFIVEPTSATLYPALLEAVERGCIDKGEEVLAPLTGSGLKTLEYFK

Sequences:

>Translated_366_residues
MAGSAEWICPRCGWSAAIGSGYYWRCPRCSGPLQLRYTRRWEPRSGCSGLAKYSSMLPLEVPRVLGEGGTPLVERRVEGV
RVFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDTSGNTGISVAAYAAAYGLRARIYMPVNAPEGKKRLVRALGGE
VVLTPSRGEAAQAVLWELKKPDVFYVAHTWSPFYVEGAKTIAFEAFEDGFRGSAVLVPVGSGGLLLGIYHGFRELVEQGL
IDSVPRIIAVQGYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEPPRLGEAAEAVKATGGCVILVDDEGIRRGLKMLASM
GFIVEPTSATLYPALLEAVERGCIDKGEEVLAPLTGSGLKTLEYFK
>Mature_365_residues
AGSAEWICPRCGWSAAIGSGYYWRCPRCSGPLQLRYTRRWEPRSGCSGLAKYSSMLPLEVPRVLGEGGTPLVERRVEGVR
VFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDTSGNTGISVAAYAAAYGLRARIYMPVNAPEGKKRLVRALGGEV
VLTPSRGEAAQAVLWELKKPDVFYVAHTWSPFYVEGAKTIAFEAFEDGFRGSAVLVPVGSGGLLLGIYHGFRELVEQGLI
DSVPRIIAVQGYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEPPRLGEAAEAVKATGGCVILVDDEGIRRGLKMLASMG
FIVEPTSATLYPALLEAVERGCIDKGEEVLAPLTGSGLKTLEYFK

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. Does not catalyze the conversion of O-acetyl-L- homoserine into threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI295821200, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI4557415, Length=209, Percent_Identity=30.1435406698565, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI11345492, Length=171, Percent_Identity=30.9941520467836, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI2367138, Length=192, Percent_Identity=30.2083333333333, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508781, Length=282, Percent_Identity=26.9503546099291, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115535073, Length=111, Percent_Identity=41.4414414414414, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71991565, Length=285, Percent_Identity=29.1228070175439, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 39675; Mature: 39544

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGSAEWICPRCGWSAAIGSGYYWRCPRCSGPLQLRYTRRWEPRSGCSGLAKYSSMLPLE
CCCCCCEECCCCCCCHHHCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCH
VPRVLGEGGTPLVERRVEGVRVFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDTS
HHHHHCCCCCHHHHHHHCEEEEEEEEEEECCCCCCCCCCCEEEEEEHHHCCEEEEEECCC
GNTGISVAAYAAAYGLRARIYMPVNAPEGKKRLVRALGGEVVLTPSRGEAAQAVLWELKK
CCCCEEHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCC
PDVFYVAHTWSPFYVEGAKTIAFEAFEDGFRGSAVLVPVGSGGLLLGIYHGFRELVEQGL
CCEEEEEECCCCEEECCCCEEEEEHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHH
IDSVPRIIAVQGYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEPPRLGEAAEAVKATGG
HHCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCEECCCCCCCHHHHHHHCCCC
CVILVDDEGIRRGLKMLASMGFIVEPTSATLYPALLEAVERGCIDKGEEVLAPLTGSGLK
EEEEECCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
TLEYFK
HHHHCC
>Mature Secondary Structure 
AGSAEWICPRCGWSAAIGSGYYWRCPRCSGPLQLRYTRRWEPRSGCSGLAKYSSMLPLE
CCCCCEECCCCCCCHHHCCCCEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCH
VPRVLGEGGTPLVERRVEGVRVFFKLEYLNPTGSFKDRGTSLALAYASRMGFRLVVEDTS
HHHHHCCCCCHHHHHHHCEEEEEEEEEEECCCCCCCCCCCEEEEEEHHHCCEEEEEECCC
GNTGISVAAYAAAYGLRARIYMPVNAPEGKKRLVRALGGEVVLTPSRGEAAQAVLWELKK
CCCCEEHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCC
PDVFYVAHTWSPFYVEGAKTIAFEAFEDGFRGSAVLVPVGSGGLLLGIYHGFRELVEQGL
CCEEEEEECCCCEEECCCCEEEEEHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHH
IDSVPRIIAVQGYSNPPLYRAVYGKEPEAEERSSRLADGLMVSEPPRLGEAAEAVKATGG
HHCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCEECCCCCCCHHHHHHHCCCC
CVILVDDEGIRRGLKMLASMGFIVEPTSATLYPALLEAVERGCIDKGEEVLAPLTGSGLK
EEEEECCHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCC
TLEYFK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]