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The map label for this gene is clpB [H]

Identifier: 123968171

GI number: 123968171

Start: 553825

End: 556407

Strand: Reverse

Name: clpB [H]

Synonym: A9601_06361

Alternate gene names: 123968171

Gene position: 556407-553825 (Counterclockwise)

Preceding gene: 123968172

Following gene: 123968169

Centisome position: 33.32

GC content: 30.43

Gene sequence:

>2583_bases
ATGAAAATAGTTCCAAGCGAATTCTCAAATTCTGCTTGGGATTGTTTTATTGTCGCCAAAGAAATTGCTTATAAAAATTA
TCAACAAAATGTAGACGCTGATAATTTATTATTAGCTCTTATTAAAGAGGACAATATTACAAAAAATATTTTAAAAAAAA
ATAATGTAAATCTAAAAGATCTTGAGAGGGAAATAATTTCTTCATTAAATGCGAAAGCAAAAATGAAAAATAAACAAGAT
AATTTATATATTGGTGAGACTCTTCACAAAATATTTTTGAAGGCGAATGATATCAAAAATACTTTAAATGATGTAGTGAT
ATCAACAGAACACTTAGTTTACTGTTTCACTTATGATAATAATTATGGATTTCAAATTTTAAATCAAAAAGGTATTCCAG
AATTTCTTGAAATTATAAAGAAAATGAAGTCAGATCCGGCATTAAATAATGAATTTAACAGTTCTAATGAGTCTTTGGAA
AAATATGGTATTGATCTAACTCAATCTGCACGAGATGGAATTTTAGACCCAGTTATTGGTAGGGATGAAGAGATTAGAAG
AACAATTCAAATATTGAGTAGAAGAACAAAAAATAATCCAGTTCTTATTGGAGAACCTGGGGTTGGCAAAACAGCCATTG
TAGAAGGTTTAGCTCAAAGAATTATTAATGGCGATGTGCCCTCTGCGCTACAAGATAGGAAACTAATTTCATTAGATATG
GGTTCACTTTTAGCTGGAGCAAAATATCGTGGAGAATTTGAAGAAAGAATAAAAAATATTCTAAAGAAAGTGAAAAAATC
AGACGGTAAGATTATTCTTTTTATTGATGAAATTCATACGGTAGTTGGCGCTGGCGCTGGTGGAGGTTCTTTAGATGCAA
GCAACCTATTAAAACCAATGCTTGCGAGAGGAGAACTTAGATGTATTGGTGCTACAACTATTAATGAACATAAACAAAAT
ATAGAAAAAGATCCTGCTTTAGAAAGAAGATTTCAAAAGATAAAAGTTGATGCTCCTTCAATAAATGACACTATATCAAT
TTTAAGAGGATTGAGAGAAAGATACGAAGTTCATCATAGTGTGAGAATTTCTGATAATGCTTTAGTTGCTGCTGCAACCC
TTAGCGAAAGATATATTAACGATAGATTTCTTCCTGACAAAGCAATAGATCTAATCGATGAAGCAGCCTCAAGATTAAAT
ATGGTCATAACTTCCAAACCTGAAGAAATTGATGAAATTGATCGAAAAGTTCTACAGTTTGAGATGGAAAAATTATCTTT
AAAAAGAGAAACGGATGATTTTTCTATAGGAAGATTAAAAAAAATCAATAATGAACTTATATCCCTTAAAGATAAACAGG
CAGAATTAGGCGCTCAATGGAAAAAAGAAAAAGATGAAATTGACGAGATTAGCACCATAAAAGAAGAAATTGAATCTGTT
CAATTGCAAATAGACCAAGCCAAAAGGAGTTTTGACCTCAACAAAGCAGCAGAATTAGAATTTGGAACTTTAAATTCTTT
GCAAAAAAAATTGAAAGAAAAAAGTGAGTCTTTAGTAAATTCCCAAAAAAATGGAGATACAAGTCTTTTAAGACAAGAGG
TAACTTTTGATGATATTGCAGAAGTTGTCTCAAAGTGGACCTCTATTCCAGTACAGAACTTAAACCAGTCAGAAAAAGAT
AAACTCTTGAGCCTCGAGTCAATCCTTAAAGAAAAAATTATTGGTCAAGATAGTGCAATTAGGGCTGTTGCAGATTCCAT
TAAGAGATCAAGGACTGGTCTAAATGATCCAAGCAAACCATTAGCCAGTTTTCTTTTTTTAGGTCCAACTGGTGTTGGGA
AAACAGAGCTAAGTAAAGTAACAGCCAAAATAATATTCGATTCAAATTCTTCAATTACAAGACTGGATATGTCTGAATAT
ATGGAAAAGCATTCAGTGAGCAAAATTATAGGTGCGCCTCCTGGATATTTAGGTTTCGAATCAGGCGGTCAACTAACTGA
AGCTGTACGCAAAAATCCTTATTCATTAATACTCCTAGATGAAATAGAGAAAGCTCACAAAGATATTTTAGATATTCTCT
TACAGGTTCTTGATGATGGAATCATTACTGATGGTCAAGGTCGTACAATCAATTTCAAAAATTCAATCATTGTTCTCACA
AGTAATTTAGGAAGTCAATCAATAAATGATTTATCAGTTAGAAAAGAAGATGCAAATGAAATTAAAAAAGTTGTAGATAA
TGAAATTAAAAAATTTTTCAAGCCTGAGTTTTTAAATCGACTTGATGAAATAGTTATTTTTAATAATTTAGAATTAAATG
ACATAAAAGAAATTGCAAAAATACAGCTTCAACATTTAGAAAAAAGACTTAACAAAAAAAACTTAAAATTCAAAATTACG
GATGAGGCAATTAACCAACTTGTCGAAAATAGTTTCGATCATGCCTATGGTGCAAGGCCTTTAAAAAGAATTATTCAAAA
ACAAATTGAGACAAAAATTTCAAATAATATATTGAATAATCATTACCTTAATAAAGACGAGATTAATATTTATCTAGTTG
ATGGAGAGATAAATGTCGATTAA

Upstream 100 bases:

>100_bases
CGCTGGAATGGTAGGTAAAGTTATTGTTGAATAAATCCTCTAAATAGTTAAAACCATTTTTGACTTAATATTTATTACGG
TCATATTCAAATTTTGATTG

Downstream 100 bases:

>100_bases
ATATCTAATTAAAGAATCCTATGTGACTTTAAAATTAACAACTTTAATCTAAGATTTGAACCAATCAGGAATTTCCTCAT
AACTTGCTTTATTCGATTTA

Product: ATP-dependent Clp protease, Hsp 100, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MKIVPSEFSNSAWDCFIVAKEIAYKNYQQNVDADNLLLALIKEDNITKNILKKNNVNLKDLEREIISSLNAKAKMKNKQD
NLYIGETLHKIFLKANDIKNTLNDVVISTEHLVYCFTYDNNYGFQILNQKGIPEFLEIIKKMKSDPALNNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRKLISLDM
GSLLAGAKYRGEFEERIKNILKKVKKSDGKIILFIDEIHTVVGAGAGGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKVDAPSINDTISILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKRETDDFSIGRLKKINNELISLKDKQAELGAQWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDANEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELNDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVDGEINVD

Sequences:

>Translated_860_residues
MKIVPSEFSNSAWDCFIVAKEIAYKNYQQNVDADNLLLALIKEDNITKNILKKNNVNLKDLEREIISSLNAKAKMKNKQD
NLYIGETLHKIFLKANDIKNTLNDVVISTEHLVYCFTYDNNYGFQILNQKGIPEFLEIIKKMKSDPALNNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRKLISLDM
GSLLAGAKYRGEFEERIKNILKKVKKSDGKIILFIDEIHTVVGAGAGGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKVDAPSINDTISILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKRETDDFSIGRLKKINNELISLKDKQAELGAQWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDANEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELNDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVDGEINVD
>Mature_860_residues
MKIVPSEFSNSAWDCFIVAKEIAYKNYQQNVDADNLLLALIKEDNITKNILKKNNVNLKDLEREIISSLNAKAKMKNKQD
NLYIGETLHKIFLKANDIKNTLNDVVISTEHLVYCFTYDNNYGFQILNQKGIPEFLEIIKKMKSDPALNNEFNSSNESLE
KYGIDLTQSARDGILDPVIGRDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRKLISLDM
GSLLAGAKYRGEFEERIKNILKKVKKSDGKIILFIDEIHTVVGAGAGGGSLDASNLLKPMLARGELRCIGATTINEHKQN
IEKDPALERRFQKIKVDAPSINDTISILRGLRERYEVHHSVRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLN
MVITSKPEEIDEIDRKVLQFEMEKLSLKRETDDFSIGRLKKINNELISLKDKQAELGAQWKKEKDEIDEISTIKEEIESV
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIAEVVSKWTSIPVQNLNQSEKD
KLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPSKPLASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEY
MEKHSVSKIIGAPPGYLGFESGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
SNLGSQSINDLSVRKEDANEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELNDIKEIAKIQLQHLEKRLNKKNLKFKIT
DEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNNHYLNKDEINIYLVDGEINVD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=37, Blast_Score=197, Evalue=3e-50,
Organism=Escherichia coli, GI1788943, Length=827, Percent_Identity=50.0604594921403, Blast_Score=828, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=406, Percent_Identity=40.8866995073892, Blast_Score=289, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=800, Percent_Identity=47.375, Blast_Score=729, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=867, Percent_Identity=39.2156862745098, Blast_Score=610, Evalue=1e-175,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97072; Mature: 97072

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVPSEFSNSAWDCFIVAKEIAYKNYQQNVDADNLLLALIKEDNITKNILKKNNVNLKD
CCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHH
LEREIISSLNAKAKMKNKQDNLYIGETLHKIFLKANDIKNTLNDVVISTEHLVYCFTYDN
HHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEEEC
NYGFQILNQKGIPEFLEIIKKMKSDPALNNEFNSSNESLEKYGIDLTQSARDGILDPVIG
CCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRKLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCEEEECH
GSLLAGAKYRGEFEERIKNILKKVKKSDGKIILFIDEIHTVVGAGAGGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKVDAPSINDTISILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKRETDDFSIGRLKKINNELISLKDKQAELGAQWKKEKDEIDEISTIKEEIESV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKDKLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPSKP
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHHCCCCCCCHHHHHHHHEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDANEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELNDIKEIAK
CCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQHLEKRLNKKNLKFKITDEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNN
HHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHC
HYLNKDEINIYLVDGEINVD
CCCCCCCEEEEEECCEEECC
>Mature Secondary Structure
MKIVPSEFSNSAWDCFIVAKEIAYKNYQQNVDADNLLLALIKEDNITKNILKKNNVNLKD
CCCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHH
LEREIISSLNAKAKMKNKQDNLYIGETLHKIFLKANDIKNTLNDVVISTEHLVYCFTYDN
HHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEECEEEEEEEEEC
NYGFQILNQKGIPEFLEIIKKMKSDPALNNEFNSSNESLEKYGIDLTQSARDGILDPVIG
CCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCC
RDEEIRRTIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGDVPSALQDRKLISLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCEEEECH
GSLLAGAKYRGEFEERIKNILKKVKKSDGKIILFIDEIHTVVGAGAGGGSLDASNLLKPM
HHHHHCCHHCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHHHH
LARGELRCIGATTINEHKQNIEKDPALERRFQKIKVDAPSINDTISILRGLRERYEVHHS
HHCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VRISDNALVAAATLSERYINDRFLPDKAIDLIDEAASRLNMVITSKPEEIDEIDRKVLQF
EEECCCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHH
EMEKLSLKRETDDFSIGRLKKINNELISLKDKQAELGAQWKKEKDEIDEISTIKEEIESV
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
QLQIDQAKRSFDLNKAAELEFGTLNSLQKKLKEKSESLVNSQKNGDTSLLRQEVTFDDIA
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHH
EVVSKWTSIPVQNLNQSEKDKLLSLESILKEKIIGQDSAIRAVADSIKRSRTGLNDPSKP
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHH
LASFLFLGPTGVGKTELSKVTAKIIFDSNSSITRLDMSEYMEKHSVSKIIGAPPGYLGFE
HHHHHHCCCCCCCHHHHHHHHEEEEECCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
SGGQLTEAVRKNPYSLILLDEIEKAHKDILDILLQVLDDGIITDGQGRTINFKNSIIVLT
CCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCEEEEE
SNLGSQSINDLSVRKEDANEIKKVVDNEIKKFFKPEFLNRLDEIVIFNNLELNDIKEIAK
CCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCHHHHHHHHH
IQLQHLEKRLNKKNLKFKITDEAINQLVENSFDHAYGARPLKRIIQKQIETKISNNILNN
HHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHC
HYLNKDEINIYLVDGEINVD
CCCCCCCEEEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]