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The map label for this gene is yciC [H]

Identifier: 123968083

GI number: 123968083

Start: 475010

End: 476161

Strand: Reverse

Name: yciC [H]

Synonym: A9601_05461

Alternate gene names: 123968083

Gene position: 476161-475010 (Counterclockwise)

Preceding gene: 123968084

Following gene: 123968082

Centisome position: 28.51

GC content: 32.12

Gene sequence:

>1152_bases
ATGTCTAAAAATTTATTGCCAGTTACAATTATTAGTGGATTTTTAGGTTCTGGCAAAACTACACTACTAAATCATATTTT
AAAAAATCAAGTTGGTATTAAAACAGCTGTTCTAGTCAACGAATTTGGAGAAATCGGAATAGATAATGACTTAATAATAG
AAGGCTCAGAAGATATGATCGAATTAAATAATGGATGTATATGTTGCTCTATCAATGGCGAGTTATTAAATACCGTATCC
AAAGTTTTAGAAAGAGCTGAAAAATTAGACTATTTGATTGTTGAAACAACTGGATTAGCAGATCCATTACCAGTAGCCAT
GACTTTTGCGGCTGGTGATCTTAGAGAAAAAGTAAGATTAGATTCGATAATCACTGTCATTGATGGCGAAAATTTTGATT
TTGAAATTAATAATACAAGTATCGCCTATTCTCAAATTTTATACGGAGATATCCTTCTTCTTAATAAATCTGATTTAGTA
AATGAAAAACAATTAAAGAAAATAGAAGAGTTTATAAATAAAATAAAAAAAGAACCAAGGATTTTGAGATCAACTAATAG
TGAAGTTGCATTACATACAATAATGAGCGTGGGTCTATTTGAGACGGATACTTTTGAATTCGAGAAAAATAAAAAAAATA
TAGAACAAAATTCCCACGATCACTCTTCTCATTCCCACGATCACTCTTCTCATTCCCACGATCACTCTTCTCATTCCCAC
GATCACTCTTCTCATTCCCACGATCACTCTTCTCATTCCCACGATCACTCTTCTCATTCCCACGATCACTCTTCTCATTC
CCACGATCACTCTTCTCATTCCCACGATCACTCTTCTCATTCCCACGATTTGATCAATAATATCGAGGGTTTTACCTCAG
TTTCATATGAGACATTTGAACCATTTTCTTTAAGGAAGTTTCAATATTTCTTAGATAATCAAATCTCAGAAAATGTATTT
AGAGCAAAAGGAATATTATGGTTTATGGAAAGTGAAAGAAAACACATTTTTCACCTATCTGGAAAGCGGTTTTCTCTAGA
TGATGAGGAATGGACAAAAGAAAAATCTAACAAGATAGTATTAATTGGGAAAAACTTAGATCACCAAACTATTAAAAATC
AACTGTCATCATGTAGATTTAATTCAGATTAG

Upstream 100 bases:

>100_bases
ATGATCTGGGAGGTATTACGAATCTGGATCAAACATTAGCTTCGGAAATCAACAAAATTTTCGATCAATAAAAATATAAA
CTTGTTTTCAACTATTCAAA

Downstream 100 bases:

>100_bases
AGTTCATATTAGGATTTAATTATTTTTTGAAAATACTTATTAAAGGATTTAAAAAAGCATTAACCGAATTAAAACTTTTT
TATTTTACTTCGTTTATTGT

Product: G3E family GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSKNLLPVTIISGFLGSGKTTLLNHILKNQVGIKTAVLVNEFGEIGIDNDLIIEGSEDMIELNNGCICCSINGELLNTVS
KVLERAEKLDYLIVETTGLADPLPVAMTFAAGDLREKVRLDSIITVIDGENFDFEINNTSIAYSQILYGDILLLNKSDLV
NEKQLKKIEEFINKIKKEPRILRSTNSEVALHTIMSVGLFETDTFEFEKNKKNIEQNSHDHSSHSHDHSSHSHDHSSHSH
DHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDLINNIEGFTSVSYETFEPFSLRKFQYFLDNQISENVF
RAKGILWFMESERKHIFHLSGKRFSLDDEEWTKEKSNKIVLIGKNLDHQTIKNQLSSCRFNSD

Sequences:

>Translated_383_residues
MSKNLLPVTIISGFLGSGKTTLLNHILKNQVGIKTAVLVNEFGEIGIDNDLIIEGSEDMIELNNGCICCSINGELLNTVS
KVLERAEKLDYLIVETTGLADPLPVAMTFAAGDLREKVRLDSIITVIDGENFDFEINNTSIAYSQILYGDILLLNKSDLV
NEKQLKKIEEFINKIKKEPRILRSTNSEVALHTIMSVGLFETDTFEFEKNKKNIEQNSHDHSSHSHDHSSHSHDHSSHSH
DHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDLINNIEGFTSVSYETFEPFSLRKFQYFLDNQISENVF
RAKGILWFMESERKHIFHLSGKRFSLDDEEWTKEKSNKIVLIGKNLDHQTIKNQLSSCRFNSD
>Mature_382_residues
SKNLLPVTIISGFLGSGKTTLLNHILKNQVGIKTAVLVNEFGEIGIDNDLIIEGSEDMIELNNGCICCSINGELLNTVSK
VLERAEKLDYLIVETTGLADPLPVAMTFAAGDLREKVRLDSIITVIDGENFDFEINNTSIAYSQILYGDILLLNKSDLVN
EKQLKKIEEFINKIKKEPRILRSTNSEVALHTIMSVGLFETDTFEFEKNKKNIEQNSHDHSSHSHDHSSHSHDHSSHSHD
HSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDLINNIEGFTSVSYETFEPFSLRKFQYFLDNQISENVFR
AKGILWFMESERKHIFHLSGKRFSLDDEEWTKEKSNKIVLIGKNLDHQTIKNQLSSCRFNSD

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=212, Percent_Identity=38.6792452830189, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI126722884, Length=212, Percent_Identity=38.6792452830189, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI223941779, Length=197, Percent_Identity=40.1015228426396, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI148727351, Length=212, Percent_Identity=38.2075471698113, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI146231952, Length=212, Percent_Identity=37.7358490566038, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI223941776, Length=202, Percent_Identity=37.1287128712871, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI119120938, Length=129, Percent_Identity=42.6356589147287, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI87082430, Length=232, Percent_Identity=36.6379310344828, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788499, Length=167, Percent_Identity=32.3353293413174, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=221, Percent_Identity=31.6742081447964, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43473; Mature: 43342

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNLLPVTIISGFLGSGKTTLLNHILKNQVGIKTAVLVNEFGEIGIDNDLIIEGSEDMI
CCCCCEEHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCEE
ELNNGCICCSINGELLNTVSKVLERAEKLDYLIVETTGLADPLPVAMTFAAGDLREKVRL
EECCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
DSIITVIDGENFDFEINNTSIAYSQILYGDILLLNKSDLVNEKQLKKIEEFINKIKKEPR
HHEEEEEECCCCEEEECCCCCHHHHHHCCCEEEECCHHCCCHHHHHHHHHHHHHHHHCCH
ILRSTNSEVALHTIMSVGLFETDTFEFEKNKKNIEQNSHDHSSHSHDHSSHSHDHSSHSH
HHHCCCCHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDLINNIEGFTSVSYETFE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCCCCC
PFSLRKFQYFLDNQISENVFRAKGILWFMESERKHIFHLSGKRFSLDDEEWTKEKSNKIV
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHCCCEEE
LIGKNLDHQTIKNQLSSCRFNSD
EEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SKNLLPVTIISGFLGSGKTTLLNHILKNQVGIKTAVLVNEFGEIGIDNDLIIEGSEDMI
CCCCEEHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEECCCCEE
ELNNGCICCSINGELLNTVSKVLERAEKLDYLIVETTGLADPLPVAMTFAAGDLREKVRL
EECCCEEEEEECHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHH
DSIITVIDGENFDFEINNTSIAYSQILYGDILLLNKSDLVNEKQLKKIEEFINKIKKEPR
HHEEEEEECCCCEEEECCCCCHHHHHHCCCEEEECCHHCCCHHHHHHHHHHHHHHHHCCH
ILRSTNSEVALHTIMSVGLFETDTFEFEKNKKNIEQNSHDHSSHSHDHSSHSHDHSSHSH
HHHCCCCHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDHSSHSHDLINNIEGFTSVSYETFE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCCCCC
PFSLRKFQYFLDNQISENVFRAKGILWFMESERKHIFHLSGKRFSLDDEEWTKEKSNKIV
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCHHHHHHCCCEEE
LIGKNLDHQTIKNQLSSCRFNSD
EEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]